DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek5 and lrrc24

DIOPT Version :9

Sequence 1:NP_001245746.1 Gene:kek5 / 32930 FlyBaseID:FBgn0031016 Length:931 Species:Drosophila melanogaster
Sequence 2:XP_009297158.1 Gene:lrrc24 / 565790 ZFINID:ZDB-GENE-060503-496 Length:692 Species:Danio rerio


Alignment Length:486 Identity:120/486 - (24%)
Similarity:190/486 - (39%) Gaps:114/486 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    22 VLVVLMALPPPTAGTTDWMQSCGT-------CHCQWNSGKKSADCKNKALTKIPQDMSNEMQVLD 79
            |||:::|            |.|.|       |.|.    ..:.:|.:..:.:|||.::...|.:.
Zfish   107 VLVLMLA------------QLCSTSLACPSGCRCY----SLTVECGSIGIKEIPQGITQGTQTIF 155

  Fly    80 FAHNQIPELRREEFLLAGLPNVHKIFLRNCTIQEVHREAFKGLHILIELDLSGNRIRELHPGTFA 144
            ...|.|.::|:.:  |:.|..:|.::|:|.:|..:...||:.|.:|:||.|:||||..:....|.
Zfish   156 LQDNAIGQIRQRD--LSDLGQLHYLYLQNNSISTLEPGAFRSLGLLLELALNGNRIHLITADVFR 218

  Fly   145 GLEKLRNVIINNNEIEVLPNHLFVNLSFLSRIEFRNNRLRQVQLHVFAGTMALSAISLEQNRLSH 209
            ||:.||.:.:..|:|..|.::.|..|..|..:..:.|.|..:......|..:|:.:.|.:|.|..
Zfish   219 GLDHLRILYLAGNQINRLEDYTFRGLQRLQELHLQENVLEVLGDQALVGLSSLALLDLSRNNLRT 283

  Fly   210 LHKETFKDLQKLMHLSLQGNAWNCSCELQDFRDF----------AISKRLYTPPTDCQEPPQLRG 264
            |...:.|.|..|..|.:..|.|.|.|.|...|.:          :..:|:.     |.|||:|..
Zfish   284 LSPASLKPLVSLQVLRVTDNPWRCDCALHWLRGWINEEGQRLLSSAERRML-----CAEPPRLSH 343

  Fly   265 KLWSEVPSENFACRPRILGSVRSFIEANH------DNISLPCRIVGSPRPNVTWVYNKRPLQQYD 323
            ....|||..:..|.|.::.     :|.:|      :::.:.|:..|.|:|.|||........|..
Zfish   344 LSLVEVPPNSLVCIPPVVQ-----LEPSHLTVRLGESLRVSCQASGYPQPQVTWRKASHGKAQLS 403

  Fly   324 PR---------------VRVLTSVEQMPEQPS--------------------QVLTSELRIVGVR 353
            ||               .|::|:.......||                    ...:..|.:..|.
Zfish   404 PRGLVQEVGMDGDTRNGGRLVTARPGGKGGPSSHGPIRGGADDGADRENFDPDTGSGMLFLSNVT 468

  Fly   354 ASDKGAYTCVADNRGGRAEAEFQLLV----------------SGDY--AGAVSAS-------DGM 393
            .:..|.|.|.|.|.||.|...|.|.|                |..|  ..:|..|       :.|
Zfish   469 VAHAGRYECEAWNPGGVARVTFHLSVNMSSSSSRSEIWPRLHSSSYYHPSSVDVSQEPLYELESM 533

  Fly   394 GMGAIGAPTIDPQTNMFLIICLIITTLLLLL 424
            ...|:|..|   ||.:.:.|.|:..|.||||
Zfish   534 DFNALGTAT---QTAIAVGISLLALTALLLL 561

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek5NP_001245746.1 LRR_RI <76..160 CDD:238064 27/83 (33%)
leucine-rich repeat 76..100 CDD:275380 6/23 (26%)
LRR_8 99..159 CDD:290566 21/59 (36%)
leucine-rich repeat 101..124 CDD:275380 7/22 (32%)
LRR 122..145 CDD:197688 10/22 (45%)
leucine-rich repeat 125..148 CDD:275380 11/22 (50%)
LRR_8 148..207 CDD:290566 14/58 (24%)
leucine-rich repeat 149..172 CDD:275380 7/22 (32%)
leucine-rich repeat 173..196 CDD:275380 4/22 (18%)
LRR_8 197..>229 CDD:290566 9/31 (29%)
leucine-rich repeat 197..220 CDD:275380 7/22 (32%)
LRRCT 229..277 CDD:214507 15/57 (26%)
Ig 296..376 CDD:143165 24/114 (21%)
lrrc24XP_009297158.1 leucine-rich repeat 151..174 CDD:275378 6/24 (25%)
LRR_8 174..257 CDD:290566 27/82 (33%)
LRR_4 174..238 CDD:289563 23/63 (37%)
leucine-rich repeat 175..222 CDD:275378 18/46 (39%)
leucine-rich repeat 199..218 CDD:275380 8/18 (44%)
LRR_8 222..304 CDD:290566 20/81 (25%)
LRR_4 222..258 CDD:289563 9/35 (26%)
leucine-rich repeat 223..246 CDD:275378 7/22 (32%)
leucine-rich repeat 247..294 CDD:275378 11/46 (24%)
leucine-rich repeat 295..307 CDD:275378 4/11 (36%)
LRRCT 303..356 CDD:214507 15/57 (26%)
IG_like 365..494 CDD:214653 27/128 (21%)
Ig 376..491 CDD:143165 24/114 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.000

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