DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek5 and LRRC26

DIOPT Version :9

Sequence 1:NP_001245746.1 Gene:kek5 / 32930 FlyBaseID:FBgn0031016 Length:931 Species:Drosophila melanogaster
Sequence 2:NP_001013675.1 Gene:LRRC26 / 389816 HGNCID:31409 Length:334 Species:Homo sapiens


Alignment Length:233 Identity:69/233 - (29%)
Similarity:96/233 - (41%) Gaps:37/233 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 RRLGMILLLLG-----VLVVLMALPPPTAGTTDWMQSCGTCHCQWNSGKKSADCKNKALTKIPQD 70
            |.|.::||||.     ..|...|.|..:.|..|..:.| ||     .....|.|...:|..:|..
Human    10 RPLLLLLLLLSPWPVWAQVSATASPSGSLGAPDCPEVC-TC-----VPGGLASCSALSLPAVPPG 68

  Fly    71 MSNEMQVLDFAHNQIPELRREEFLLAGLPNVHKIFLRNCTIQEVHREAFKGLHILIELDLSGNRI 135
            :|..::.|...||::..|....|  ||...:.::.||...:..||..||.||..|..||||.|::
Human    69 LSLRLRALLLDHNRVRALPPGAF--AGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQL 131

  Fly   136 RELHPGTFAGLEKLRNVIINNNEIEVLPNHLFVNLSFLSRIEFRNNRLRQVQLHVFAGTMALSAI 200
            ..|.|||||.|..|||                        :....|||.:::.........|.::
Human   132 EALAPGTFAPLRALRN------------------------LSLAGNRLARLEPAALGALPLLRSL 172

  Fly   201 SLEQNRLSHLHKETFKDLQKLMHLSLQGNAWNCSCELQ 238
            ||:.|.|:.|.......|..|..|.|:||.|.|.|.|:
Human   173 SLQDNELAALAPGLLGRLPALDALHLRGNPWGCGCALR 210

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek5NP_001245746.1 LRR_RI <76..160 CDD:238064 31/83 (37%)
leucine-rich repeat 76..100 CDD:275380 7/23 (30%)
LRR_8 99..159 CDD:290566 24/59 (41%)
leucine-rich repeat 101..124 CDD:275380 8/22 (36%)
LRR 122..145 CDD:197688 12/22 (55%)
leucine-rich repeat 125..148 CDD:275380 13/22 (59%)
LRR_8 148..207 CDD:290566 10/58 (17%)
leucine-rich repeat 149..172 CDD:275380 3/22 (14%)
leucine-rich repeat 173..196 CDD:275380 3/22 (14%)
LRR_8 197..>229 CDD:290566 10/31 (32%)
leucine-rich repeat 197..220 CDD:275380 7/22 (32%)
LRRCT 229..277 CDD:214507 5/10 (50%)
Ig 296..376 CDD:143165
LRRC26NP_001013675.1 LRR 1 72..93 5/22 (23%)
LRR 2 96..117 6/20 (30%)
LRR_RI 97..>253 CDD:238064 43/138 (31%)
LRR_8 97..155 CDD:290566 25/81 (31%)
leucine-rich repeat 97..120 CDD:275380 8/22 (36%)
LRR 3 120..141 11/20 (55%)
leucine-rich repeat 121..144 CDD:275380 13/22 (59%)
LRR_8 143..202 CDD:290566 17/82 (21%)
LRR 4 144..167 6/46 (13%)
leucine-rich repeat 145..168 CDD:275380 6/46 (13%)
LRR 5 168..190 6/21 (29%)
leucine-rich repeat 169..192 CDD:275380 7/22 (32%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 298..334
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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