DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kek5 and AgaP_AGAP011373

DIOPT Version :9

Sequence 1:	NP_001245746.1	Gene:	kek5 / 32930	FlyBaseID:	FBgn0031016	Length:	931	Species:	Drosophila melanogaster
Sequence 2:	XP_554872.3	Gene:	AgaP_AGAP011373 / 3291302	VectorBaseID:	AGAP011373	Length:	240	Species:	Anopheles gambiae

Alignment Length:	152	Identity:	47/152 - (30%)
Similarity:	77/152 - (50%)	Gaps:	2/152 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 LDFAHNQIPELRREEFLLAGLPNVHKIFLRNCTIQEVHREAFKGLHILIELDLSGNRIRELHPGT 142
            |...:|:|..:..:.|  ||:..:..:.||...|::|.:..|:.|..|.||:|..|:|..|||..
Mosquito    29 LHLNNNKIASIGNKTF--AGMDELRVLNLRGNFIEQVTKGLFRALPKLEELNLGENQIATLHPEA 91

  Fly   143 FAGLEKLRNVIINNNEIEVLPNHLFVNLSFLSRIEFRNNRLRQVQLHVFAGTMALSAISLEQNRL 207
            |.||..||.:.:::|.|.|:|...|..|..|:.:....|.|.|:|...|.|...|..:.:..:.|
Mosquito    92 FEGLPYLRILHLDDNAINVIPTPSFTPLRLLAELYLGLNTLNQIQPGSFEGLQHLRRLDVRGSML 156

  Fly   208 SHLHKETFKDLQKLMHLSLQGN 229
            .:|..:||:.|:.:..|.:..|
Mosquito   157 VNLTIDTFRGLENVRSLDISDN 178

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kek5	NP_001245746.1	LRR_RI	<76..160	CDD:238064	27/81 (33%)
		leucine-rich repeat	76..100	CDD:275380	6/21 (29%)
		LRR_8	99..159	CDD:290566	21/59 (36%)
		leucine-rich repeat	101..124	CDD:275380	6/22 (27%)
		LRR	122..145	CDD:197688	11/22 (50%)
		leucine-rich repeat	125..148	CDD:275380	12/22 (55%)
		LRR_8	148..207	CDD:290566	16/58 (28%)
		leucine-rich repeat	149..172	CDD:275380	8/22 (36%)
		leucine-rich repeat	173..196	CDD:275380	7/22 (32%)
		LRR_8	197..>229	CDD:290566	7/31 (23%)
		leucine-rich repeat	197..220	CDD:275380	6/22 (27%)
		LRRCT	229..277	CDD:214507	1/1 (100%)
		Ig	296..376	CDD:143165
AgaP_AGAP011373	XP_554872.3	LRR_RI	<2..>150	CDD:238064	40/122 (33%)
		LRR_8	2..58	CDD:290566	8/30 (27%)
		leucine-rich repeat	2..25	CDD:275380
		leucine-rich repeat	26..49	CDD:275380	6/21 (29%)
		LRR_8	49..108	CDD:290566	21/58 (36%)
		leucine-rich repeat	50..73	CDD:275380	6/22 (27%)
		leucine-rich repeat	74..97	CDD:275380	12/22 (55%)
		leucine-rich repeat	98..121	CDD:275380	8/22 (36%)
		LRR_8	120..180	CDD:290566	15/59 (25%)
		leucine-rich repeat	122..145	CDD:275380	7/22 (32%)
		leucine-rich repeat	146..169	CDD:275380	6/22 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910