DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek5 and Lrtm1

DIOPT Version :9

Sequence 1:NP_001245746.1 Gene:kek5 / 32930 FlyBaseID:FBgn0031016 Length:931 Species:Drosophila melanogaster
Sequence 2:NP_795894.1 Gene:Lrtm1 / 319476 MGIID:2442106 Length:356 Species:Mus musculus


Alignment Length:316 Identity:70/316 - (22%)
Similarity:123/316 - (38%) Gaps:61/316 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 GMILLLLGVLVVLMALPPPTAGTTDWMQSCGTC--HCQWNSGKKSADCKNKALTKIPQDMSNEMQ 76
            |.:||:..|.::|..:              |:|  .|..:....|.||..:.|:|:|:|:.    
Mouse    15 GTLLLVSSVGLLLPGV--------------GSCPMKCLCHPSSNSVDCSGQGLSKVPRDLP---- 61

  Fly    77 VLDFAHNQIPELRREEFLLAGLPNVHKIFLRNCTIQEVHREAFKGLHILIELDLSGNRIRELHPG 141
                                  |....:.|::..|..:...||:.:.:|..|:||.|.:..|...
Mouse    62 ----------------------PWTVTLLLQDNRIHWLPALAFQSVSLLSTLNLSNNSLSNLAAE 104

  Fly   142 TFAGLEKLRNVIINNNEIEVLPNHLFVNLSFLSRIEFRNNRLRQVQLHVFAGTMALSAISLEQNR 206
            .|.||..||.:.:..|.:..:.:.....|..|..::..:|.||.:...:......|:..:::||.
Mouse   105 AFYGLPHLRVLNVTQNSLLSIESSFAHALPGLRELDLSSNSLRILPTSLGKPWENLTVFAVQQNH 169

  Fly   207 LSHLHKETFKDLQKLMHLSLQGNAWNCSCELQDFRDFAISKRLYTPPTD---CQEPPQLRGKLWS 268
            |.||.:|..:.:.|:..:.|:.|.|.|.|.|...:.:..........||   |:.|...:||...
Mouse   170 LLHLDRELLEAMPKVRLVLLKDNPWICDCHLLGLKLWLERFTFQGGETDGAICRLPEPWQGKALL 234

  Fly   269 EVPSENF-AC-------RPRIL---GSVRSFIEANHDNIS-----LPCRIVGSPRP 308
            .:|.|.: .|       .|.::   ||.....:.:|:|.|     |.|.....|:|
Mouse   235 SIPHELYQPCSLPSQDLAPSLVQQPGSAPQDAQKSHENSSGQQDPLECEAKPKPKP 290

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek5NP_001245746.1 LRR_RI <76..160 CDD:238064 17/83 (20%)
leucine-rich repeat 76..100 CDD:275380 0/23 (0%)
LRR_8 99..159 CDD:290566 17/59 (29%)
leucine-rich repeat 101..124 CDD:275380 4/22 (18%)
LRR 122..145 CDD:197688 7/22 (32%)
leucine-rich repeat 125..148 CDD:275380 9/22 (41%)
LRR_8 148..207 CDD:290566 11/58 (19%)
leucine-rich repeat 149..172 CDD:275380 4/22 (18%)
leucine-rich repeat 173..196 CDD:275380 4/22 (18%)
LRR_8 197..>229 CDD:290566 9/31 (29%)
leucine-rich repeat 197..220 CDD:275380 7/22 (32%)
LRRCT 229..277 CDD:214507 13/51 (25%)
Ig 296..376 CDD:143165 5/18 (28%)
Lrtm1NP_795894.1 LRRNT 33..62 CDD:214470 9/54 (17%)
leucine-rich repeat 45..63 CDD:275380 7/43 (16%)
LRR 1 63..84 4/20 (20%)
leucine-rich repeat 64..111 CDD:275378 13/46 (28%)
LRR 2 87..108 7/20 (35%)
LRR_8 110..170 CDD:290566 11/59 (19%)
LRR_4 110..151 CDD:289563 8/40 (20%)
LRR 3 111..132 3/20 (15%)
leucine-rich repeat 112..135 CDD:275378 4/22 (18%)
LRR 4 135..156 4/20 (20%)
leucine-rich repeat 136..159 CDD:275378 4/22 (18%)
LRR 5 159..180 7/20 (35%)
leucine-rich repeat 160..183 CDD:275378 7/22 (32%)
leucine-rich repeat 184..196 CDD:275378 3/11 (27%)
TPKR_C2 192..239 CDD:301599 12/46 (26%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 255..288 7/32 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X1203
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.000

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