DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek5 and Lrrc26

DIOPT Version :9

Sequence 1:NP_001245746.1 Gene:kek5 / 32930 FlyBaseID:FBgn0031016 Length:931 Species:Drosophila melanogaster
Sequence 2:NP_001014075.1 Gene:Lrrc26 / 311803 RGDID:1308398 Length:334 Species:Rattus norvegicus


Alignment Length:296 Identity:84/296 - (28%)
Similarity:114/296 - (38%) Gaps:63/296 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MMGNRTERSGRRLGMILLLLGVLVVLMALPPPTAGTTDWMQS-CGT--------------CHCQW 50
            |.|:...|...:|.::||||.:|          :....|.|. .||              |.|  
  Rat     1 MRGSFFSRLPPQLSLLLLLLLLL----------SWRRVWTQEHIGTDPSKSPVAPVCPEACSC-- 53

  Fly    51 NSGKKSADCKNKALTKIPQDMSNEMQVLDFAHNQIPELRREEFLLAGLPNVHKIFLRNCTIQEVH 115
            :.|.| |:|...||..:|..:|.:::.|....|::..|....|..||.  :..:.||...::.||
  Rat    54 SPGGK-ANCSALALPAVPAGLSWQVRSLLLDRNRVSTLPPGAFADAGA--LLYLVLRENRLRSVH 115

  Fly   116 REAFKGLHILIELDLSGNRIRELHPGTFAGLEKLRNVIINNNEIEVLPNHLFVNLSFLSRIEFRN 180
            ..||.||.:|..||||.|::..|.||||..|..                     |||||   ...
  Rat   116 ARAFWGLGVLQRLDLSSNQLETLSPGTFTPLRA---------------------LSFLS---LAG 156

  Fly   181 NRLRQVQLHVFAGTMALSAISLEQNRLSHLHKETFKDLQKLMHLSLQGNAWNCSCELQDFRDFAI 245
            |||..::..:......|..:||:.|.||.|.......|..|..|.|.||.|.|||.|   |....
  Rat   157 NRLALLEPSILGPLPLLRVLSLQDNSLSALEAGLLNSLPALDVLRLHGNPWACSCAL---RPLCT 218

  Fly   246 SKRLYTPPTD------CQEPPQLRGKLWSEVPSENF 275
            ..|.:..||.      |..|......|.::.|...|
  Rat   219 WLRKHPRPTSETETLLCVSPKLQTLNLLTDFPDNAF 254

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek5NP_001245746.1 LRR_RI <76..160 CDD:238064 26/83 (31%)
leucine-rich repeat 76..100 CDD:275380 6/23 (26%)
LRR_8 99..159 CDD:290566 20/59 (34%)
leucine-rich repeat 101..124 CDD:275380 8/22 (36%)
LRR 122..145 CDD:197688 12/22 (55%)
leucine-rich repeat 125..148 CDD:275380 12/22 (55%)
LRR_8 148..207 CDD:290566 12/58 (21%)
leucine-rich repeat 149..172 CDD:275380 1/22 (5%)
leucine-rich repeat 173..196 CDD:275380 5/22 (23%)
LRR_8 197..>229 CDD:290566 11/31 (35%)
leucine-rich repeat 197..220 CDD:275380 8/22 (36%)
LRRCT 229..277 CDD:214507 15/53 (28%)
Ig 296..376 CDD:143165
Lrrc26NP_001014075.1 LRR_8 76..135 CDD:290566 20/60 (33%)
LRR 1 76..97 4/20 (20%)
leucine-rich repeat 77..100 CDD:275380 5/22 (23%)
LRR 2 100..121 6/22 (27%)
leucine-rich repeat 101..124 CDD:275380 8/22 (36%)
LRR 3 124..145 11/20 (55%)
LRR_8 125..183 CDD:290566 24/81 (30%)
LRR_4 125..164 CDD:289563 20/62 (32%)
leucine-rich repeat 125..148 CDD:275380 12/22 (55%)
LRR 4 148..169 8/44 (18%)
leucine-rich repeat 149..172 CDD:275380 8/25 (32%)
LRR 5 172..194 7/21 (33%)
leucine-rich repeat 173..196 CDD:275380 8/22 (36%)
leucine-rich repeat 197..239 CDD:275380 15/44 (34%)
TPKR_C2 205..258 CDD:301599 15/53 (28%)
leucine-rich repeat 240..259 CDD:275380 3/15 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 312..334
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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