Protein Alignment kek5 and Flrt2

DIOPT Version :9

• Sequence 1: NP_001245746.1
• Gene: kek5 / 32930
• FlyBaseID: FBgn0031016
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: NP_001100220.1
• Gene: Flrt2 / 299236
• RGDID: 1308574
• Length: 660
• Species: Rattus norvegicus
• Alignment Length: 723
• Identity: 135/723 - (18%)
• Similarity: 220/723 - (30%)
• Gaps: 267/723 - (36%)

  Fly    16 ILLLLGV---LVVLMALPPPTAGTTDWMQSCGTCHCQWNSGKKSADCKNKALTKIPQDMSNEMQV 77
            :::.||:   :..|:|.|             ..|.|..|    ...|..::||.:|..:...:.|
  Rat    20 LIMSLGLYSHVSKLLACP-------------SVCRCDRN----FVYCNERSLTSVPLGIPEGVTV 67

  Fly    78 LDFAHNQI------PELRR--------------EEFLLAGLP-NVHKIFLRNCTIQEVHREAFKG 121
            |...:|||      .||..              :||.: .|| ||..:.|:...||.:.|.|...
  Rat    68 LYLHNNQINNAGFPAELHNVQSVHTVYLYGNQLDEFPM-NLPKNVRVLHLQENNIQTISRAALAQ 131

  Fly   122 LHILIELDLSGNRIRE--LHPGTF------------------------AGLEKLRNVIINNNEIE 160
            |..|.||.|..|.|..  :..|.|                        ..|::||   ::.|.|.
  Rat   132 LLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPVDLQELR---VDENRIA 193

  Fly   161 VLPNHLFVNLSFLSRI------------------------EF----------------------- 178
            |:.:..|.||:.|.|:                        ||
  Rat   194 VISDMAFQNLTSLERLIVDGNLLTNKGIADGTFSHLTKLKEFSIVRNSLSHPPPDLPGTHLIRLY 258

  Fly   179 -RNNRLRQVQLHVFAGTMALSAISLEQNRLSHLHKETFKDLQKLMHLSLQGNAWNCSCELQDFRD 242
             ::|::..:.|..||....|..:.:..|:|..|.:..|..|..|..|:.:.|.|.|.|.::...:
  Rat   259 LQDNQINHIPLTAFANLRKLERLDISNNQLRMLTQGVFDHLSNLKQLTARNNPWFCDCSIKWVTE 323

  Fly   243 FA--ISKRLYTPPTDCQEPPQLRGKLWSEVPSENFACRPRILGSVRSFIEA--------NHDNIS 297
            :.  |...|......||.|.|:||....|:.....:| |.....:..|..|        ....:|
  Rat   324 WLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSC-PTTTPGLPVFTPAPSTVSPTTQSPTVS 387

  Fly   298 LPCRIVGS----PRPN------------------------------------------------V 310
            :|....||    |.|:                                                :
  Rat   388 VPSPSRGSVPPAPAPSKLPTIPDWDGRERATPPISERIQLSIHFVNDTSIQVSWLSLFTVMAYKL 452

  Fly   311 TWVYNKRPLQQYDPRVRVLTSVEQMPEQPSQVLTSELRIVGVRASDKGAYTCVADNRGGRAEAEF 375
            |||.....|.....:.|:::..:|.....:....|..||..| ..|...|..|.|.....|....
  Rat   453 TWVKMGHSLVGGIVQERIVSGEKQHLSLVNLEPRSTYRICLV-PLDAFNYRTVEDTICSEATTHA 516

  Fly   376 QLLVSGDYAGAVSASDGMGMGAIGAPTIDPQTNMFLIICLIITTLLLLLLVAVLTLFWYCRRIKT 440
            ..|.:|  :...|:.:......:|:|        ||:..||...::.:|:|.:....|:..:...
  Rat   517 SYLNNG--SNTASSHEQTTSHTMGSP--------FLLAGLIGGAVIFVLVVLLSVFCWHMHKKGR 571

  Fly   441 Y-----------QKDTTMMSGDGLISSKMDKT---------HNGSMLEGSVIMEMQKSLLNEVNP 485
            |           :||....:|....:|.::.|         :|..:|:|..          .:.|
  Rat   572 YTSQKWKYNRGRRKDDYCEAGTKKDNSILEMTETSFQIVSLNNDQLLKGDF----------RLQP 626

  Fly   486 VEKPPRRTDIESVDGGDDVLEIKKTLLDDTVYVANHSRDEEAVSVAMSDTTTTPRSRHTYVDDAY 550
            :..|         :||.:..:         .::.|:.|                          |
  Rat   627 IYTP---------NGGINYTD---------CHIPNNMR--------------------------Y 647

  Fly   551 ANSLPPDL 558
            .||..|||
  Rat   648 CNSSVPDL 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kek5	NP_001245746.1	LRR_RI	<76..160	CDD:238064	31/130 (24%)
		leucine-rich repeat	76..100	CDD:275380	11/44 (25%)
		LRR_8	99..159	CDD:290566	21/86 (24%)
		leucine-rich repeat	101..124	CDD:275380	7/22 (32%)
		LRR	122..145	CDD:197688	9/48 (19%)
		leucine-rich repeat	125..148	CDD:275380	9/48 (19%)
		LRR_8	148..207	CDD:290566	18/106 (17%)
		leucine-rich repeat	149..172	CDD:275380	8/22 (36%)
		leucine-rich repeat	173..196	CDD:275380	8/70 (11%)
		LRR_8	197..>229	CDD:290566	8/31 (26%)
		leucine-rich repeat	197..220	CDD:275380	6/22 (27%)
		LRRCT	229..277	CDD:214507	13/49 (27%)
		Ig	296..376	CDD:143165	21/131 (16%)
Flrt2	NP_001100220.1	LRRNT	35..66	CDD:214470	9/47 (19%)
		LRR 1. /evidence=ECO:0000255	62..87		7/24 (29%)
		leucine-rich repeat	65..86	CDD:275378	7/20 (35%)
		LRR 2. /evidence=ECO:0000255	88..108		2/20 (10%)
		PPP1R42	89..311	CDD:411060	45/225 (20%)
		leucine-rich repeat	90..110	CDD:275380	4/20 (20%)
		LRR 3. /evidence=ECO:0000255	109..131		7/21 (33%)
		leucine-rich repeat	111..134	CDD:275380	7/22 (32%)
		LRR 4. /evidence=ECO:0000255	132..157		9/24 (38%)
		leucine-rich repeat	135..160	CDD:275380	8/24 (33%)
		LRR 5. /evidence=ECO:0000255	159..181		0/21 (0%)
		leucine-rich repeat	161..181	CDD:275380	0/19 (0%)
		leucine-rich repeat	182..205	CDD:275380	9/25 (36%)
		LRR 6. /evidence=ECO:0000255	183..202		6/21 (29%)
		LRR 7. /evidence=ECO:0000255	203..228		3/24 (13%)
		leucine-rich repeat	206..231	CDD:275380	2/24 (8%)
		LRR 8. /evidence=ECO:0000255	229..251		2/21 (10%)
		leucine-rich repeat	232..253	CDD:275380	2/20 (10%)
		LRR 9. /evidence=ECO:0000255	252..274		3/21 (14%)
		leucine-rich repeat	254..277	CDD:275380	4/22 (18%)
		LRR 10. /evidence=ECO:0000255	275..298		5/22 (23%)
		leucine-rich repeat	278..301	CDD:275380	6/22 (27%)
		PCC	282..>359	CDD:188093	20/76 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	372..413		7/40 (18%)
		fn3	426..494	CDD:394996	9/67 (13%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000