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Protein Alignment kek5 and Lrig2

DIOPT Version :9

Sequence 1:	NP_001245746.1	Gene:	kek5 / 32930	FlyBaseID:	FBgn0031016	Length:	931	Species:	Drosophila melanogaster
Sequence 2:	NP_001020238.1	Gene:	Lrig2 / 269473	MGIID:	2443718	Length:	1054	Species:	Mus musculus

Alignment Length:	708	Identity:	135/708 - (19%)
Similarity:	243/708 - (34%)	Gaps:	204/708 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 NEMQVLDFAHNQIPELRREEFLLAGLPNVHKIFLRNCTIQEVHREAFKGLHILIELDLSGNRIRE 137
            |.|:.|:..||.:..:.:.  .|.||..:.::::....|:::..:|::....|.|||||.|::..
Mouse   262 NNMEELELEHNNLTGVNKG--WLYGLRMLQQLYMSQNAIEKISPDAWEFCQRLSELDLSYNQLTR 324

  Fly   138 LHPGTFAGLEKLRNVIINNNEIEVLPNHLFVNLSFLSRIEFRNNRLR---QVQLHVFAGTMALSA 199
            |....|.||..|..:.:.:|.:..:.:.:|..||.|..::.|||.:.   :.....|:|..:|:.
Mouse   325 LDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNDISWAIEDASEAFSGLKSLTK 389

  Fly   200 ISLEQNRLSHLHKETFKDLQKLMHL--------SLQGNAWN---------------CSCELQDFR 241
            :.|:.||:..:.::.|..|:.|.:|        |:|.||::               |.|.|:...
Mouse   390 LILQGNRIKSVTQKAFIGLESLEYLDLNNNAIMSIQENAFSQTHLKGLVLNTSSLLCDCHLKWLL 454

  Fly   242 DFAISKRL-YTPPTDCQEPPQLRGKLWSEVPSENFAC----RPRILGSVRSFIEANHDNISLPCR 301
            .:.:.... ::....|..|..|.|:....|..::|.|    :|:|.....|.|.....|::|.|.
Mouse   455 QWLVDNNFHHSVNVSCAHPEWLAGQSILNVDLKDFVCDDFLKPQIRTHPESTIALRGVNVTLTCT 519

  Fly   302 IVGSPRPNVTWVYNKRPLQQYDPRVRVLTSVEQMPEQPSQVL--TSELRIVGVRASDKGAYTCVA 364
            .|.|....::.::.|.....||..:.......|   |..:.|  ||.||:..|..:|:|.|.|:.
Mouse   520 AVSSSDSPMSTIWRKDSEILYDVDIENFVRYRQ---QDGEALEYTSVLRLFSVNFTDEGKYQCIV 581

  Fly   365 DNR-GGRAEAEFQLLVSG---------DYAGAVSASDGMGMGAIGAPT----------------- 402
            .|. |.....:.:|.|:.         |......|...:...|.|.||
Mouse   582 TNHFGSNYSQKAKLTVNEMPSFLKTPMDLTIRTGAMARLECAAEGHPTPQISWQKDGGTDFPAAR 646

  Fly   403 -----IDPQTNMFLIICLIITTLLLLLLVAVLTLFWYCRRIKTYQKDTTMMSGDGLISSKMDKTH 462
                 :.|:.::|.|..:.|..:                               |:.|.......
Mouse   647 ERRMHVMPEDDVFFIANVKIEDM-------------------------------GIYSCMAQNIA 680

  Fly   463 NGSMLEGSVIMEMQKSLLNEVNPVE-KPPRRTD---IESVDGGDDVLEIKKTLLDDTVYVANHS- 522
            .|.....|:.:....|.   :.|:| |...|.:   ::.:.||.....:..|..|..:.|....
Mouse   681 GGLSANASLTVLETPSF---IRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLLVTERHF 742

  Fly   523 ---------------RDEEAVSVAMSDTTTTPRSRHTYVDDAYANSLPPDLLAFPARVPPTSPSM 572
                           .|....:..||:|..|.|. |.|::..                  :||:.
Mouse   743 FAAANQLLIIVDAGLEDAGKYTCLMSNTLGTERG-HIYLNVI------------------SSPNC 788

  Fly   573 QSSQSNIPDQ---------------------------VIYGIR-----------SPPSLTSPVYT 599
            .||||:|..:                           |||.:|           ...:|.:.:.:
Mouse   789 DSSQSSIGHEDDGWTTVGIVIIVVVCCVVGTSLIWVIVIYHMRRKNEDYSITNTEELNLPADIPS 853

  Fly   600 HMTPHGIYGTKTMTAPHNGFMTLQHPKSRNLALIATTNSSRQHQHHHQLQQQQQHHHH 657
            :::..|     |::.|..|:                  |:.:...|.||......:.|
Mouse   854 YLSSQG-----TLSEPQEGY------------------SNSEAGSHQQLMPPANGYTH 888

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.