DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek5 and Lrit1

DIOPT Version :9

Sequence 1:NP_001245746.1 Gene:kek5 / 32930 FlyBaseID:FBgn0031016 Length:931 Species:Drosophila melanogaster
Sequence 2:NP_647547.2 Gene:Lrit1 / 246214 RGDID:628607 Length:623 Species:Rattus norvegicus


Alignment Length:397 Identity:100/397 - (25%)
Similarity:145/397 - (36%) Gaps:72/397 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    39 WMQSCGTCHCQWNSGKKSADCK-------NKALTKIPQDMSNEMQVLDFAHNQIPELRREEFLLA 96
            |:.:.|..|..|:.......|.       :||.|.:..|..     |......||          
  Rat     9 WLLALGGPHQAWSFCPSQCSCSLHILSDGSKARTVVCSDPD-----LTLPPASIP---------- 58

  Fly    97 GLPNVHKIFLRNCTIQEVHREAFKGLHILIELDLSGNRIRELHPGTFAGLEKLRNVIINNNEIEV 161
              |:..|:.|....|:.|..|.|:.|..|.:|.|..|.:.||......||.:||.:.:..|.:..
  Rat    59 --PDTCKLRLERTAIRRVPGETFRPLSRLEQLWLPYNALSELSTLMLRGLRRLRELRLPGNHLVT 121

  Fly   162 LPNHLFVNLSFLSRIEFRNNRLRQVQLHVFAGTMALSAISLEQNRLSHLHKE---TFKDLQKLMH 223
            .|.....:...|..::.:.|||..:..........|:.:.|..|:|..|.:|   |:..|:...:
  Rat   122 FPWAALKDTPQLQLLDLQANRLSTLPPEAVHFLENLTFLDLSNNQLMRLPEELLDTWAHLKTGPY 186

  Fly   224 LS---------LQGNAWNCSCELQDFRDFA---------ISKRLYTPPTDCQEPPQLRGKLWSEV 270
            ||         ||.|.|.|.|.|.|.....         |..||     .|..|..|.|..:|::
  Rat   187 LSSRRTRLVLGLQDNPWVCDCRLYDLVHLLDGWASNLIFIEARL-----RCGSPRSLAGVAFSQL 246

  Fly   271 PSENFACR-PRILGSVRSFIEANHDNISLPCRIVGSPRPNVTW-VYNKRPLQQYDPRVRVLTSVE 333
              |...|: |.:...|.|.|......:.|.|...|.|.|.::| ..|.|||..        |..:
  Rat   247 --ELRKCQSPELRPGVTSIISPLGSTVLLRCGATGIPGPEMSWRRANGRPLNG--------TVHQ 301

  Fly   334 QMPEQPSQVLTSELRIVGVRASDKGAYTCVADNRGGRAEAEFQLLV-----SGDYA---GAVSAS 390
            ::....|.....:|.:|.:  .|.|.|.|.|.|..|.:|....|:|     |.:|.   ||:.|.
  Rat   302 EVSSDGSSWTLLDLPVVSL--FDSGDYICQAKNFLGASETLISLIVTEPQTSTEYTGIPGALWAR 364

  Fly   391 DGMGMGA 397
            .|.|..|
  Rat   365 TGEGAEA 371

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek5NP_001245746.1 LRR_RI <76..160 CDD:238064 22/83 (27%)
leucine-rich repeat 76..100 CDD:275380 3/23 (13%)
LRR_8 99..159 CDD:290566 19/59 (32%)
leucine-rich repeat 101..124 CDD:275380 7/22 (32%)
LRR 122..145 CDD:197688 7/22 (32%)
leucine-rich repeat 125..148 CDD:275380 8/22 (36%)
LRR_8 148..207 CDD:290566 11/58 (19%)
leucine-rich repeat 149..172 CDD:275380 4/22 (18%)
leucine-rich repeat 173..196 CDD:275380 4/22 (18%)
LRR_8 197..>229 CDD:290566 12/43 (28%)
leucine-rich repeat 197..220 CDD:275380 8/25 (32%)
LRRCT 229..277 CDD:214507 15/56 (27%)
Ig 296..376 CDD:143165 22/80 (28%)
Lrit1NP_647547.2 LRRNT 23..61 CDD:214470 9/54 (17%)
LRR 1 60..81 6/20 (30%)
LRR_8 63..143 CDD:290566 21/79 (27%)
leucine-rich repeat 64..84 CDD:275378 6/19 (32%)
LRR 2 84..105 6/20 (30%)
leucine-rich repeat 85..132 CDD:275378 12/46 (26%)
LRR 3 108..128 4/19 (21%)
LRR_8 131..>176 CDD:290566 10/44 (23%)
LRR_4 131..172 CDD:289563 9/40 (23%)
LRR 4 132..153 4/20 (20%)
leucine-rich repeat 133..156 CDD:275378 4/22 (18%)
LRR 5 156..177 6/20 (30%)
leucine-rich repeat 157..180 CDD:275378 7/22 (32%)
leucine-rich repeat 181..205 CDD:275378 7/23 (30%)
TPKR_C2 201..>240 CDD:301599 12/43 (28%)
Ig 257..345 CDD:299845 26/97 (27%)
IG_like 267..345 CDD:214653 23/87 (26%)
FN3 431..501 CDD:214495
LRR 6 525..548
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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