DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment kek5 and PHLPP1

DIOPT Version :9

Sequence 1:NP_001245746.1 Gene:kek5 / 32930 FlyBaseID:FBgn0031016 Length:931 Species:Drosophila melanogaster
Sequence 2:NP_919431.2 Gene:PHLPP1 / 23239 HGNCID:20610 Length:1717 Species:Homo sapiens


Alignment Length: Identity:/ - (0%)
Similarity:/ - (0%) Gaps:/ - (0%)


- Green bases have known domain annotations that are detailed below.


Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek5NP_001245746.1 LRR_RI <76..160 CDD:238064
leucine-rich repeat 76..100 CDD:275380
LRR_8 99..159 CDD:290566
leucine-rich repeat 101..124 CDD:275380
LRR 122..145 CDD:197688
leucine-rich repeat 125..148 CDD:275380
LRR_8 148..207 CDD:290566
leucine-rich repeat 149..172 CDD:275380
leucine-rich repeat 173..196 CDD:275380
LRR_8 197..>229 CDD:290566
leucine-rich repeat 197..220 CDD:275380
LRRCT 229..277 CDD:214507
Ig 296..376 CDD:143165
PHLPP1NP_919431.2 leucine-rich repeat 1107..1129 CDD:275380
PP2Cc 1168..1420 CDD:214625
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1458..1510
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1673..1717
PDZ-binding, required for interaction with SLC9A3R1. /evidence=ECO:0000269|PubMed:21804599 1715..1717
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..25
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 41..118
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 136..156
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 252..470
PH_PHLPP-like 535..631 CDD:270131
PH 555..636 CDD:278594
LRR_RI 625..929 CDD:238064
LRR_8 638..703 CDD:290566
LRR 1 638..659
leucine-rich repeat 641..661 CDD:275380
LRR 2 661..682
leucine-rich repeat 662..692 CDD:275380
LRR 3 692..712
leucine-rich repeat 693..738 CDD:275380
LRR_8 714..770 CDD:290566
LRR 4 715..736
LRR 5 738..760
leucine-rich repeat 739..761 CDD:275380
LRR 6 761..783
leucine-rich repeat 762..784 CDD:275380
LRR 7 784..804
leucine-rich repeat 785..808 CDD:275380
LRR 8 808..831
leucine-rich repeat 810..832 CDD:275380
LRR_RI 814..1074 CDD:238064
LRR 9 832..853
leucine-rich repeat 833..853 CDD:275380
leucine-rich repeat 854..895 CDD:275380
LRR 10 873..894
LRR 11 895..916
leucine-rich repeat 896..918 CDD:275380
LRR 12 918..939
leucine-rich repeat 919..941 CDD:275380
LRR 13 941..962
leucine-rich repeat 942..963 CDD:275380
LRR_8 962..1024 CDD:290566
LRR 14 963..984
leucine-rich repeat 964..987 CDD:275380
LRR 15 987..1008
leucine-rich repeat 988..1011 CDD:275380
LRR 16 1013..1033
LRR_8 1014..1072 CDD:290566
leucine-rich repeat 1014..1037 CDD:275380
LRR 17 1037..1058
leucine-rich repeat 1038..1061 CDD:275380
LRR 18 1061..1082
Interaction with SLC9A3R1. /evidence=ECO:0000269|PubMed:21804599 1076..1205
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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