DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek5 and Gp5

DIOPT Version :9

Sequence 1:NP_001245746.1 Gene:kek5 / 32930 FlyBaseID:FBgn0031016 Length:931 Species:Drosophila melanogaster
Sequence 2:NP_032174.2 Gene:Gp5 / 14729 MGIID:1096363 Length:567 Species:Mus musculus


Alignment Length:213 Identity:58/213 - (27%)
Similarity:93/213 - (43%) Gaps:13/213 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly    78 LDFAHNQIPELRREEFLLAGLPNVHKIFLRNCTIQEVHREAFKGLHILIELDLSGN-RIRELHPG 141
            |....|.:.||  .:.|...:..:.:::|....:..:...||:.|..|..|.|:.| |:..|..|
Mouse   271 LTLFENPLEEL--PDVLFGEMAGLRELWLNGTHLSTLPAAAFRNLSGLQTLGLTRNPRLSALPRG 333

  Fly   142 TFAGLEKLRNVIINNNEIEVLPNHLFVNLSFLSRIEFRNNRLRQVQLHVFAGTMALSAISLEQNR 206
            .|.||.:||.:.::.|.:..|.:.....|..|.::..|:||||.:...:|....:|.::.||.|:
Mouse   334 VFQGLRELRVLALHTNALAELRDDALRGLGHLRQVSLRHNRLRALPRTLFRNLSSLESVQLEHNQ 398

  Fly   207 LSHLHKETFKDLQKLMHLSLQGNAWNCSCELQDFRDFAISKRLYTPPTDCQEPPQLRG------- 264
            |..|..:.|..|.:|..:.|..|.|.|.|.|..|..:.   |.:.......||||.||       
Mouse   399 LETLPGDVFAALPQLTQVLLGHNPWLCDCGLWPFLQWL---RHHPDILGRDEPPQCRGPEPRASL 460

  Fly   265 KLWSEVPSENFACRPRIL 282
            ..|..:..:.:...||.|
Mouse   461 SFWELLQGDPWCPDPRSL 478

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek5NP_001245746.1 LRR_RI <76..160 CDD:238064 22/82 (27%)
leucine-rich repeat 76..100 CDD:275380 5/21 (24%)
LRR_8 99..159 CDD:290566 17/60 (28%)
leucine-rich repeat 101..124 CDD:275380 4/22 (18%)
LRR 122..145 CDD:197688 9/23 (39%)
leucine-rich repeat 125..148 CDD:275380 10/23 (43%)
LRR_8 148..207 CDD:290566 16/58 (28%)
leucine-rich repeat 149..172 CDD:275380 5/22 (23%)
leucine-rich repeat 173..196 CDD:275380 7/22 (32%)
LRR_8 197..>229 CDD:290566 10/31 (32%)
leucine-rich repeat 197..220 CDD:275380 8/22 (36%)
LRRCT 229..277 CDD:214507 14/54 (26%)
Ig 296..376 CDD:143165
Gp5NP_032174.2 LRR 1 75..96
LRR_8 76..134 CDD:290566
leucine-rich repeat 76..99 CDD:275380
LRR 2 99..120
leucine-rich repeat 100..123 CDD:275380
LRR 3 123..144
LRR_8 124..182 CDD:290566
leucine-rich repeat 124..147 CDD:275380
LRR_RI 126..402 CDD:238064 36/132 (27%)
LRR 4 147..168
leucine-rich repeat 148..171 CDD:275380
LRR 5 171..193
leucine-rich repeat 172..195 CDD:275380
LRR_8 195..254 CDD:290566
LRR 6 195..216
leucine-rich repeat 196..219 CDD:275380
LRR 7 219..240
leucine-rich repeat 220..243 CDD:275380
LRR_8 243..302 CDD:290566 6/32 (19%)
LRR 8 243..264
leucine-rich repeat 244..267 CDD:275380
LRR 9 267..288 5/18 (28%)
leucine-rich repeat 268..291 CDD:275380 5/21 (24%)
LRR 10 291..312 3/20 (15%)
leucine-rich repeat 292..315 CDD:275380 4/22 (18%)
LRR_8 314..375 CDD:290566 18/60 (30%)
LRR 11 315..337 8/21 (38%)
leucine-rich repeat 316..338 CDD:275380 8/21 (38%)
LRR 12 340..361 4/20 (20%)
leucine-rich repeat 341..364 CDD:275380 5/22 (23%)
LRR_8 364..422 CDD:290566 17/57 (30%)
LRR 13 364..385 7/20 (35%)
leucine-rich repeat 365..388 CDD:275380 7/22 (32%)
LRR 14 388..409 7/20 (35%)
leucine-rich repeat 389..410 CDD:275380 7/20 (35%)
TPKR_C2 421..>454 CDD:301599 12/35 (34%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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