DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment kek5 and AgaP_AGAP002793

DIOPT Version :9

Sequence 1:	NP_001245746.1	Gene:	kek5 / 32930	FlyBaseID:	FBgn0031016	Length:	931	Species:	Drosophila melanogaster
Sequence 2:	XP_312121.5	Gene:	AgaP_AGAP002793 / 1273169	VectorBaseID:	AGAP002793	Length:	1451	Species:	Anopheles gambiae

Alignment Length:	412	Identity:	89/412 - (21%)
Similarity:	133/412 - (32%)	Gaps:	162/412 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 QSC-GTCHCQWNSGKKSADCKNKALTKIPQDM----------SNEMQ---------------VLD 79
            |.| ..|||.    :.:.||..:.|.:||:|:          .||:.               .||
Mosquito   486 QECPAACHCD----RTTVDCSGRGLKEIPRDIPLYTTELLLNDNELNRIKSDGLFGRLPNLAKLD 546

  Fly    80 FAHNQIPELRREEFLLAGLPNVHKIFLRNCTIQEVHREAFKGLHIL------------------- 125
            ...|||..:....|  .|...:.::||....|.|||.:.|.|||.|
Mosquito   547 LRRNQISGIEPNAF--EGATRIQELFLSENKIAEVHNKMFLGLHQLKTLSLYDNIITCVMPGSFD 609

  Fly   126 ----------------------------------------------------------------- 125

Mosquito   610 YLTSLTQLNLASNPFRCNCHLAWFSDWLRKKQLNGPPARCTSPSKVRDVPIKDLPHFDFKCTSDM 674

  Fly   126 ---------------------------------------IELDLSGNRIRELHPGTFAGLEKLRN 151
                                                   .||.|..|.|..:|....:.|:.|..
Mosquito   675 DQGCLGEGYCPPSCTCTGTVVRCSRNKLKEIPKSIPAETTELYLESNEISMIHSNRISHLKALTR 739

  Fly   152 VIINNNEIEVLPNHLFVNLSFLSRIEFRNNRLRQVQLHVFAGTMALSAISLEQNRLSHLHKETFK 216
            :.::||:|.:|.||.|.|||.||.:....|.|:.||.:..||...|..:||..|::|.:.:.||.
Mosquito   740 LDLSNNQIGILSNHTFANLSKLSTLIISYNNLQCVQKYALAGLTNLKVLSLHGNKISMIPEGTFN 804

  Fly   217 DLQKLMHLSLQGNAWNCSCELQDFRDFAISKRLYTPP--TDCQEPPQLRGKLWSEVPSENFACRP 279
            |||.:.|::|..|...|.|.|:...::.  ||.|..|  ..|.||..::.||....|:..|.|..
Mosquito   805 DLQSITHIALGSNPLYCDCSLRWLSEWV--KRDYVEPGIARCAEPEPMKDKLILSTPAAQFVCSG 867

  Fly   280 RILGSVRSFIEANHDNISLPCR 301
            ::...:.|..:|.:   :.||:
Mosquito   868 KVSNEILSKCDACY---TFPCK 886

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kek5	NP_001245746.1	LRR_RI	<76..160	CDD:238064	28/221 (13%)
		leucine-rich repeat	76..100	CDD:275380	7/38 (18%)
		LRR_8	99..159	CDD:290566	21/182 (12%)
		leucine-rich repeat	101..124	CDD:275380	9/22 (41%)
		LRR	122..145	CDD:197688	9/145 (6%)
		leucine-rich repeat	125..148	CDD:275380	8/145 (6%)
		LRR_8	148..207	CDD:290566	23/58 (40%)
		leucine-rich repeat	149..172	CDD:275380	10/22 (45%)
		leucine-rich repeat	173..196	CDD:275380	8/22 (36%)
		LRR_8	197..>229	CDD:290566	12/31 (39%)
		leucine-rich repeat	197..220	CDD:275380	9/22 (41%)
		LRRCT	229..277	CDD:214507	15/49 (31%)
		Ig	296..376	CDD:143165	2/6 (33%)
AgaP_AGAP002793	XP_312121.5	leucine-rich repeat	517..541	CDD:275380	2/23 (9%)
		LRR_8	540..598	CDD:290566	18/59 (31%)
		leucine-rich repeat	542..565	CDD:275380	7/24 (29%)
		leucine-rich repeat	566..589	CDD:275380	9/22 (41%)
		leucine-rich repeat	590..613	CDD:275380	1/22 (5%)
		leucine-rich repeat	614..665	CDD:275380	0/50 (0%)
		LRRCT	622..671	CDD:214507	0/48 (0%)
		leucine-rich repeat	666..736	CDD:275380	7/69 (10%)
		leucine-rich repeat	679..712	CDD:275380	0/32 (0%)
		LRRNT	684..715	CDD:214470	0/30 (0%)
		LRR_RI	<715..>819	CDD:238064	39/103 (38%)
		LRR_8	737..795	CDD:290566	23/57 (40%)
		leucine-rich repeat	737..760	CDD:275380	10/22 (45%)
		leucine-rich repeat	761..784	CDD:275380	8/22 (36%)
		LRR	782..805	CDD:197688	7/22 (32%)
		leucine-rich repeat	785..806	CDD:275380	7/20 (35%)
		LRRCT	817..866	CDD:214507	15/50 (30%)
		EGF_CA	878..913	CDD:238011	3/12 (25%)
		EGF_CA	916..952	CDD:238011
		EGF_CA	954..990	CDD:238011
		EGF_CA	999..1030	CDD:238011
		EGF_CA	1032..1068	CDD:238011
		Laminin_G_1	1148..1279	CDD:278483
		GHB_like	1382..1451	CDD:304424
		LRR_RI	<43..201	CDD:238064
		LRR_8	51..105	CDD:290566
		leucine-rich repeat	51..70	CDD:275380
		leucine-rich repeat	71..94	CDD:275380
		LRR_8	94..153	CDD:290566
		leucine-rich repeat	95..118	CDD:275380
		leucine-rich repeat	119..142	CDD:275380
		LRR_8	141..201	CDD:290566
		leucine-rich repeat	143..166	CDD:275380
		leucine-rich repeat	167..190	CDD:275380
		leucine-rich repeat	191..262	CDD:275380
		LRRCT	199..248	CDD:214507
		leucine-rich repeat	263..316	CDD:275380
		LRRNT	264..295	CDD:214470
		leucine-rich repeat	274..292	CDD:275380
		LRR_8	294..351	CDD:290566
		LRR_4	316..356	CDD:289563
		leucine-rich repeat	317..340	CDD:275380
		leucine-rich repeat	341..361	CDD:275380
		leucine-rich repeat	365..385	CDD:275380
		LRR_8	371..423	CDD:290566
		LRR_RI	<381..603	CDD:238064	31/122 (25%)
		leucine-rich repeat	389..410	CDD:275380
		LRRCT	421..470	CDD:214507
		LRRNT	488..519	CDD:214470	10/34 (29%)
		leucine-rich repeat	497..515	CDD:275380	6/17 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910