DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kek5 and AgaP_AGAP012635

DIOPT Version :9

Sequence 1:	NP_001245746.1	Gene:	kek5 / 32930	FlyBaseID:	FBgn0031016	Length:	931	Species:	Drosophila melanogaster
Sequence 2:	XP_307249.3	Gene:	AgaP_AGAP012635 / 1268683	VectorBaseID:	AGAP012635	Length:	561	Species:	Anopheles gambiae

Alignment Length:	191	Identity:	55/191 - (28%)
Similarity:	91/191 - (47%)	Gaps:	2/191 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 CHCQWNSGKKSADCKNKALTKIPQDMSNEMQVLDFAHNQIPELRREEFLLAGLPNVHKIFLRNCT 110
            |.|......|.|||.|:.|.....|:..::::||.:.|.|..:..|.|:  ...|:.|:||...:
Mosquito     9 CSCDVIEDLKRADCSNEKLINTYTDVPYDVEILDLSINIISTIENENFM--HYDNLVKLFLSENS 71

  Fly   111 IQEVHREAFKGLHILIELDLSGNRIRELHPGTFAGLEKLRNVIINNNEIEVLPNHLFVNLSFLSR 175
            ||.:..:||.....|..||||.||:..|:...|....:|.::.::.|...:|||..|:....:..
Mosquito    72 IQTISLDAFANQQRLTTLDLSYNRLEHLNEHLFERNLQLVDLNLSGNNFMMLPNTPFLKSYSIMF 136

  Fly   176 IEFRNNRLRQVQLHVFAGTMALSAISLEQNRLSHLHKETFKDLQKLMHLSLQGNAWNCSCE 236
            :...:.|:..|...:|.....|.::.|.:|.::.|....|..|:||..|:|..|.|:|..|
Mosquito   137 LHLASCRIPHVFDTMFIDLPNLKSLDLAKNIMNSLSTVPFAHLRKLNSLNLMDNRWDCKTE 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kek5	NP_001245746.1	LRR_RI	<76..160	CDD:238064	25/83 (30%)
		leucine-rich repeat	76..100	CDD:275380	6/23 (26%)
		LRR_8	99..159	CDD:290566	19/59 (32%)
		leucine-rich repeat	101..124	CDD:275380	7/22 (32%)
		LRR	122..145	CDD:197688	9/22 (41%)
		leucine-rich repeat	125..148	CDD:275380	9/22 (41%)
		LRR_8	148..207	CDD:290566	12/58 (21%)
		leucine-rich repeat	149..172	CDD:275380	6/22 (27%)
		leucine-rich repeat	173..196	CDD:275380	3/22 (14%)
		LRR_8	197..>229	CDD:290566	10/31 (32%)
		leucine-rich repeat	197..220	CDD:275380	6/22 (27%)
		LRRCT	229..277	CDD:214507	4/8 (50%)
		Ig	296..376	CDD:143165
AgaP_AGAP012635	XP_307249.3	LRR_RI	37..>190	CDD:238064	42/154 (27%)
		leucine-rich repeat	38..61	CDD:275380	6/24 (25%)
		LRR_8	61..120	CDD:290566	19/58 (33%)
		LRR_4	61..101	CDD:289563	16/39 (41%)
		leucine-rich repeat	62..85	CDD:275380	7/22 (32%)
		leucine-rich repeat	86..109	CDD:275380	9/22 (41%)
		leucine-rich repeat	110..133	CDD:275380	6/22 (27%)
		leucine-rich repeat	134..157	CDD:275380	3/22 (14%)
		LRR_8	137..191	CDD:290566	13/53 (25%)
		leucine-rich repeat	158..181	CDD:275380	6/22 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910