DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek5 and lrfn4a

DIOPT Version :9

Sequence 1:NP_001245746.1 Gene:kek5 / 32930 FlyBaseID:FBgn0031016 Length:931 Species:Drosophila melanogaster
Sequence 2:XP_005161420.1 Gene:lrfn4a / 101882983 ZFINID:ZDB-GENE-091113-56 Length:892 Species:Danio rerio


Alignment Length:452 Identity:108/452 - (23%)
Similarity:167/452 - (36%) Gaps:100/452 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 LGMILLLLGVLVVLMALPPPTAGTTDWMQSCGTCHCQWNSGKKSAD--CKNKALTKIPQDMSNEM 75
            ||.:||..|..|:        ||.|..|.|....||...:..:|..  |.||.|..:|.::....
Zfish    58 LGSVLLQSGQGVM--------AGETWGMVSICPFHCVCRNLSESLSTLCVNKGLLFVPPNIDRRT 114

  Fly    76 QVLDFAHNQIPELRREEFLLAGLPNVHKIFLRNCTIQEVHREAFKGLHILIELDLSGNRIRELHP 140
            ..|..|.|.|.|:...:|  |.:..:..:.|...||..:...||..|..|..|.|..||:..:.|
Zfish   115 VELRLADNYILEVGGADF--ANMTGLVDLTLSRNTIHALKPLAFADLESLRSLHLDTNRLTVVGP 177

  Fly   141 GTFAGLEKLRNVIINNNEIEVLPNHLFVN-LSFLSRIEFRNNRLRQVQLHVFAGTMALSAISLEQ 204
            ....||..|:::|||||::..:....|.: |..|..::...|.||:|.........:|..::|:.
Zfish   178 QDLTGLVNLQHLIINNNQLTDVSADAFDDFLLTLEDLDLSYNNLRRVPWESIQNMASLHTLNLDH 242

  Fly   205 NRLSHLHKETFKDLQKLMHLSLQ-----------------------------------GNAWNCS 234
            |.:..:.:.:|.:|.||..|.:.                                   ||..:|:
Zfish   243 NLIDQIAEGSFGELYKLSRLDMTSNRLQTLPPDPLFSRSQIGVVSPTPYNSITSLNFGGNPLHCN 307

  Fly   235 CELQDFRDFAISKRLYTPPTDCQEPPQLRGKLWSEVPSENFACRPRILGSVRSFIEANHDNI--- 296
            |||...|.......:.|    |..|..|.|:.:..:|.|.|.|.|.:       |..|.:.:   
Zfish   308 CELLWLRRLIREDDMET----CATPAHLAGRYFWSIPEEEFTCEPPL-------ITRNTNKLWVL 361

  Fly   297 -----SLPCRIVGSPRPNVTWVYNKRPLQQYDPRVRVLTSVEQMPEQPSQVLTSELRIVGVRASD 356
                 :|.||.:|.|.|.:.||         .|..|::.:..::    .......|..:..||.|
Zfish   362 EGQRATLKCRAIGDPEPVIHWV---------SPDDRIVANSSRI----RSYYNGTLDFLVTRARD 413

  Fly   357 KGAYTCVADNRGGRAEAEFQLLV--------------------SGDYAGAVSASDGMGMGAI 398
            .|.|||:|.|..|.:.|...|.:                    |.|.:......:|.|.|.:
Zfish   414 DGTYTCIAINAAGESTALVDLKIIPLPHRGNGTISLINHRDPGSSDISSGRGGVEGTGNGVV 475

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek5NP_001245746.1 LRR_RI <76..160 CDD:238064 27/83 (33%)
leucine-rich repeat 76..100 CDD:275380 7/23 (30%)
LRR_8 99..159 CDD:290566 20/59 (34%)
leucine-rich repeat 101..124 CDD:275380 6/22 (27%)
LRR 122..145 CDD:197688 7/22 (32%)
leucine-rich repeat 125..148 CDD:275380 8/22 (36%)
LRR_8 148..207 CDD:290566 16/59 (27%)
leucine-rich repeat 149..172 CDD:275380 8/23 (35%)
leucine-rich repeat 173..196 CDD:275380 5/22 (23%)
LRR_8 197..>229 CDD:290566 8/66 (12%)
leucine-rich repeat 197..220 CDD:275380 5/22 (23%)
LRRCT 229..277 CDD:214507 14/47 (30%)
Ig 296..376 CDD:143165 22/87 (25%)
lrfn4aXP_005161420.1 LRR_RI 102..>269 CDD:238064 44/168 (26%)
leucine-rich repeat 114..137 CDD:275380 7/24 (29%)
LRR_8 136..196 CDD:290566 20/59 (34%)
leucine-rich repeat 138..161 CDD:275380 6/22 (27%)
leucine-rich repeat 162..185 CDD:275380 8/22 (36%)
LRR_8 185..245 CDD:290566 16/59 (27%)
leucine-rich repeat 186..210 CDD:275380 8/23 (35%)
leucine-rich repeat 211..234 CDD:275380 5/22 (23%)
LRR_8 234..304 CDD:290566 10/69 (14%)
leucine-rich repeat 235..258 CDD:275380 5/22 (23%)
leucine-rich repeat 259..282 CDD:275380 2/22 (9%)
LRRCT 302..346 CDD:214507 14/47 (30%)
IG_like 358..436 CDD:214653 23/90 (26%)
Ig 363..436 CDD:299845 23/85 (27%)
fn3 501..579 CDD:278470
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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