DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek5 and lrfn5

DIOPT Version :9

Sequence 1:NP_001245746.1 Gene:kek5 / 32930 FlyBaseID:FBgn0031016 Length:931 Species:Drosophila melanogaster
Sequence 2:XP_002941802.2 Gene:lrfn5 / 100495182 XenbaseID:XB-GENE-923445 Length:775 Species:Xenopus tropicalis


Alignment Length:403 Identity:94/403 - (23%)
Similarity:156/403 - (38%) Gaps:86/403 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 RLGMILLLLGVLVVLMALPPPTAGTTDWMQSCGTCHCQWNSGKKSADCKNKALTKIPQDMSNEMQ 76
            :|...||.:|:.|.....|.             .|.||..|...:..|..|.|..:|.:::.:..
 Frog     3 KLFCYLLFIGMAVRAEICPK-------------RCACQNLSPNLATLCDKKGLLFVPPNINRKTV 54

  Fly    77 VLDFAHNQIPELRREEFLLAGLPNVHKIFLRNCTIQEVHREAFKGLHILIELDLSGNRIRELHPG 141
            .|..|.|.:..::|::|  |.:.::..:.|...||..:...||..|..|..|.|:.||:..:...
 Frog    55 ELRLADNFVTSIKRKDF--ANMTSLVDLTLSRNTISYITPHAFSDLRNLRALHLNSNRLTRVAND 117

  Fly   142 TFAGLEKLRNVIINNNEIEVLPNHLFVNLSFLSRIEFRNNRLRQVQLHVFAGTMALSAISLEQNR 206
            .|:||..|.::|:|||::.::.:..|.::..|..::...|.|..:........::|..:||:.|.
 Frog   118 MFSGLLNLHHLILNNNQLTLISSTAFDDVLALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNM 182

  Fly   207 LSHLHKETFKDLQKL-----------------------------------MHLSLQGNAWNCSCE 236
            :.|:.|.||..|.||                                   ..||..||..:|:||
 Frog   183 IEHIPKGTFSHLHKLNRLDVTSNKLQKLPPDPLFQRAQVLVTSGIISSSTFALSFGGNPLHCNCE 247

  Fly   237 LQDFRDFAISKRLYTPPTDCQEPPQLRGKLWSEVPSENFACRP----------RILGSVRSFIEA 291
            |...|.......|.|    |..||.|.|:.:..:..|.|.|.|          |:|...|:    
 Frog   248 LLWLRRLLREDDLET----CASPPLLSGRYFWSITEEEFLCEPPLITRYTQELRVLEGQRA---- 304

  Fly   292 NHDNISLPCRIVGSPRPNVTWVYNKRPLQQYDPRVRVLTSVEQMPEQPSQVLTSELRIVGVRASD 356
                 :|.|:.:|.|.|.:.|:..:..|.....|:.|..:             ..|.|:.....|
 Frog   305 -----TLRCKALGDPEPAIHWISPESKLISNGTRILVYDN-------------GTLDILITTVKD 351

  Fly   357 KGAYTCVADNRGG 369
            .|:::|:|.|..|
 Frog   352 TGSFSCIASNPAG 364

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek5NP_001245746.1 LRR_RI <76..160 CDD:238064 25/83 (30%)
leucine-rich repeat 76..100 CDD:275380 6/23 (26%)
LRR_8 99..159 CDD:290566 19/59 (32%)
leucine-rich repeat 101..124 CDD:275380 6/22 (27%)
LRR 122..145 CDD:197688 7/22 (32%)
leucine-rich repeat 125..148 CDD:275380 8/22 (36%)
LRR_8 148..207 CDD:290566 13/58 (22%)
leucine-rich repeat 149..172 CDD:275380 6/22 (27%)
leucine-rich repeat 173..196 CDD:275380 3/22 (14%)
LRR_8 197..>229 CDD:290566 13/66 (20%)
leucine-rich repeat 197..220 CDD:275380 9/22 (41%)
LRRCT 229..277 CDD:214507 15/47 (32%)
Ig 296..376 CDD:143165 17/74 (23%)
lrfn5XP_002941802.2 leucine-rich repeat 53..76 CDD:275380 6/24 (25%)
LRR_8 55..111 CDD:404697 16/57 (28%)
leucine-rich repeat 77..100 CDD:275380 6/22 (27%)
leucine-rich repeat 101..124 CDD:275380 8/22 (36%)
leucine-rich repeat 125..148 CDD:275380 6/22 (27%)
LRR_8 149..207 CDD:404697 14/57 (25%)
leucine-rich repeat 149..172 CDD:275380 3/22 (14%)
leucine-rich repeat 173..196 CDD:275380 9/22 (41%)
leucine-rich repeat 197..215 CDD:275380 1/17 (6%)
leucine-rich repeat 222..244 CDD:275378 4/21 (19%)
Ig 287..374 CDD:416386 20/100 (20%)
Ig strand A 287..290 CDD:409353 0/2 (0%)
Ig strand A' 294..297 CDD:409353 0/2 (0%)
Ig strand B 303..311 CDD:409353 3/16 (19%)
Ig strand C 317..322 CDD:409353 1/4 (25%)
Ig strand C' 325..327 CDD:409353 0/1 (0%)
Ig strand D 333..337 CDD:409353 1/3 (33%)
Ig strand E 340..344 CDD:409353 1/3 (33%)
Ig strand F 354..361 CDD:409353 2/6 (33%)
Ig strand G 364..374 CDD:409353 1/1 (100%)
FN3 422..495 CDD:419708
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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