DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kek5 and XB6050834

DIOPT Version :9

Sequence 1:	NP_001245746.1	Gene:	kek5 / 32930	FlyBaseID:	FBgn0031016	Length:	931	Species:	Drosophila melanogaster
Sequence 2:	XP_017944840.1	Gene:	XB6050834 / 100488256	XenbaseID:	XB-GENE-6050835	Length:	353	Species:	Xenopus tropicalis

Alignment Length:	309	Identity:	75/309 - (24%)
Similarity:	130/309 - (42%)	Gaps:	61/309 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LLGVLVVLMALPPPTAGTTDWMQSC-GTCHCQWNSGKKSADCKNKALTKIPQDMSNEMQVLDFAH 82
            :|.:|.:|:.:.|   ..::.:|:| ..|.|..:|  ...:|:|:.|..:|..:|:...:||..|
Frog     1 MLELLPLLLIIVP---SYSNIVQNCPNFCLCYESS--NLVECRNQNLLSVPHHLSHSTWMLDLRH 60

  Fly    83 NQIPELRREEFLLAGLPNVHKIFLRNCTIQEVHREAFKGLHILIELDLSGNR------------- 134
            |.:..|....|  ..|.::..:.|.:..|::|...:|:.|..|..||||.|:
Frog    61 NNLSRLDPASF--QALWSLRILLLSDNRIEKVSPRSFRSLGFLERLDLSYNQLSSLPFDFSRGLG 123

  Fly   135 -IREL----------------------------------HPGTFAGLEKLRNVIINNNEIEVLPN 164
             :|||                                  ..|.|.||.:||::.:.:|.:..:..
Frog   124 SLRELRVPSNRLTVLSYESLRHLESLEKLDLSKNFLASVEQGAFRGLSRLRHLHLQSNLLYAIRG 188

  Fly   165 HLFVNLSFLSRIEFRNNRLRQVQLHVFAGTMALSAISLEQNRLSHLHKETFKDLQ-KLMHLSLQG 228
            ..|..|..|..::..:|.:..:.:..|....:|..::|..|:||||..:||.::| ...|:.:.|
Frog   189 GYFFMLQNLELLDLSDNNISSIAVESFTSLHSLRLLALSDNQLSHLKFKTFINIQTPSTHMQVSG 253

  Fly   229 NAWNCSCELQD-FRDFAISKRLYTPPTD---CQEPPQLRGKLWSEVPSE 273
            |.|.|.|:||. |......:.|:....:   |..||||.|.....|.|:
Frog   254 NPWVCDCDLQRVFGKINSVRHLHIDDYENLTCAGPPQLLGAALDSVDSQ 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kek5	NP_001245746.1	LRR_RI	<76..160	CDD:238064	28/131 (21%)
		leucine-rich repeat	76..100	CDD:275380	7/23 (30%)
		LRR_8	99..159	CDD:290566	21/107 (20%)
		leucine-rich repeat	101..124	CDD:275380	5/22 (23%)
		LRR	122..145	CDD:197688	12/70 (17%)
		leucine-rich repeat	125..148	CDD:275380	13/70 (19%)
		LRR_8	148..207	CDD:290566	11/58 (19%)
		leucine-rich repeat	149..172	CDD:275380	5/22 (23%)
		leucine-rich repeat	173..196	CDD:275380	3/22 (14%)
		LRR_8	197..>229	CDD:290566	11/32 (34%)
		leucine-rich repeat	197..220	CDD:275380	10/23 (43%)
		LRRCT	229..277	CDD:214507	16/49 (33%)
		Ig	296..376	CDD:143165
XB6050834	XP_017944840.1	LRR	<34..>234	CDD:227223	43/201 (21%)
		leucine-rich repeat	53..76	CDD:275380	7/24 (29%)
		leucine-rich repeat	77..100	CDD:275380	5/22 (23%)
		leucine-rich repeat	101..124	CDD:275380	6/22 (27%)
		leucine-rich repeat	125..148	CDD:275380	3/22 (14%)
		leucine-rich repeat	149..172	CDD:275380	4/22 (18%)
		leucine-rich repeat	173..196	CDD:275380	5/22 (23%)
		leucine-rich repeat	197..220	CDD:275380	3/22 (14%)
		PCC	226..>296	CDD:188093	25/69 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	53	1.000	Domainoid score	I11184
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000