DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek5 and slitrk3a

DIOPT Version :9

Sequence 1:NP_001245746.1 Gene:kek5 / 32930 FlyBaseID:FBgn0031016 Length:931 Species:Drosophila melanogaster
Sequence 2:XP_021323398.1 Gene:slitrk3a / 100334261 ZFINID:ZDB-GENE-130226-1 Length:871 Species:Danio rerio


Alignment Length:380 Identity:92/380 - (24%)
Similarity:145/380 - (38%) Gaps:107/380 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    19 LLGVLVVLMALPPPTAGTTDWM-QSC-GTCHCQWNSGKKSADCKNKALTKIPQDMSNEMQ--VLD 79
            ||..:.:....|.|....::.: :.| ..|:|:...|.....|.:|..|.:.|......:  .|:
Zfish     6 LLSTIALGWTTPIPLLDESEEIDEPCFDPCYCEVKEGIFHVHCDSKGFTNVSQISQTWTRPFKLN 70

  Fly    80 FAHNQIPELRREEFLLAGLPNVHKIFLRNCTIQEVHREAFKGLHILIELDLSGNR---------- 134
            ...|.:.:|....||  .|.|...:.|.|..:|::|..||.||.||.:|.|..|:          
Zfish    71 LQRNSMRKLYFNSFL--HLNNAVSLNLGNNALQDIHVGAFNGLSILKKLFLHENKLEVFRNDTFM 133

  Fly   135 --------------IRELHPGTFAGLEKLRNVIINNNEIEVLPNHLFVNLSFLSRIEFRNNRLRQ 185
                          |:.:..|.|..|.|||.:|:|:|.|.||||.||.::| |:.::.|.|||| 
Zfish   134 GLESLEYLQADYNVIKRIESGAFRNLHKLRVLILNDNLIPVLPNLLFRSVS-LTHLDLRGNRLR- 196

  Fly   186 VQLHVFAGTMALSAISLEQNRLSHLHKETFKDLQKLMHLSLQGNAWNCSCELQDFRDFAISKRLY 250
              :..:.||:....                   :.||.:.|:.|.|||.|::...:.: :.:..|
Zfish   197 --ILPYKGTLEYIG-------------------RSLMEIQLEENPWNCVCDIVQLKTW-LERIPY 239

  Fly   251 TP---PTDCQEPPQLRGK------------LWSEVPSENFACRPRILGSVRSFIEANHDNI--SL 298
            |.   ...|:.|..|.||            |.||...|.....||        :..|::|:  :.
Zfish   240 TALVGDITCEYPFHLHGKDLREIKRSELCPLLSEAELEAKHGIPR--------LPFNNENVWPTK 296

  Fly   299 PCRIVGS--------------------PRPNVT-----WVY---NKRPLQQYDPR 325
            |..::.|                    |||..|     .:|   |:.|:..|..|
Zfish   297 PSSMLSSFHNTASSVEYRERHVKPTKRPRPTKTPPTPRSIYPGLNQPPIAAYQTR 351

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek5NP_001245746.1 LRR_RI <76..160 CDD:238064 30/109 (28%)
leucine-rich repeat 76..100 CDD:275380 6/25 (24%)
LRR_8 99..159 CDD:290566 24/83 (29%)
leucine-rich repeat 101..124 CDD:275380 8/22 (36%)
LRR 122..145 CDD:197688 9/46 (20%)
leucine-rich repeat 125..148 CDD:275380 8/46 (17%)
LRR_8 148..207 CDD:290566 22/58 (38%)
leucine-rich repeat 149..172 CDD:275380 12/22 (55%)
leucine-rich repeat 173..196 CDD:275380 8/22 (36%)
LRR_8 197..>229 CDD:290566 3/31 (10%)
leucine-rich repeat 197..220 CDD:275380 0/22 (0%)
LRRCT 229..277 CDD:214507 16/62 (26%)
Ig 296..376 CDD:143165 11/60 (18%)
slitrk3aXP_021323398.1 leucine-rich repeat 68..89 CDD:275380 6/22 (27%)
LRR_8 92..148 CDD:316378 13/55 (24%)
leucine-rich repeat 92..113 CDD:275380 8/20 (40%)
leucine-rich repeat 114..137 CDD:275380 4/22 (18%)
LRR_8 137..195 CDD:316378 21/58 (36%)
leucine-rich repeat 138..161 CDD:275380 4/22 (18%)
leucine-rich repeat 162..184 CDD:275380 12/21 (57%)
leucine-rich repeat 185..365 CDD:275380 42/198 (21%)
leucine-rich repeat 211..270 CDD:275380 15/59 (25%)
TPKR_C2 219..269 CDD:326558 12/50 (24%)
leucine-rich repeat 374..394 CDD:275380
leucine-rich repeat 396..418 CDD:275378
LRR_8 417..477 CDD:316378
leucine-rich repeat 419..442 CDD:275378
leucine-rich repeat 443..466 CDD:275378
leucine-rich repeat 467..490 CDD:275378
LRR_8 489..548 CDD:316378
leucine-rich repeat 491..504 CDD:275378
leucine-rich repeat 514..538 CDD:275380
LRRCT 547..597 CDD:214507
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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