DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek5 and btk

DIOPT Version :9

Sequence 1:NP_001245746.1 Gene:kek5 / 32930 FlyBaseID:FBgn0031016 Length:931 Species:Drosophila melanogaster
Sequence 2:NP_001123732.1 Gene:btk / 100170477 XenbaseID:XB-GENE-6451230 Length:649 Species:Xenopus tropicalis


Alignment Length:378 Identity:70/378 - (18%)
Similarity:123/378 - (32%) Gaps:131/378 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   555 PPDLLAFPARVPPTSPSMQSSQSNI------PDQVIYGIRSPPSLTSPVYTHMTPHGIYGTKTMT 613
            ||     |.|..|......:.|..|      |.|::|.       ..|:|.              
 Frog    75 PP-----PERQIPNREEFDTEQMTIIERFPYPFQIVYD-------DGPLYV-------------- 113

  Fly   614 APHNGFMTLQHPKSR---NLALIATTNSSRQHQHHHQLQQQQQHHHHHQ---------------- 659
                 |...:..:.|   .|..:...||....::|.:..|..|:....|                
 Frog   114 -----FAPTEELRKRWIHQLKHVIRFNSDVAQKYHPRFYQDGQYLCCAQTAKNAMGCQPLGNANG 173

  Fly   660 --QQQQQQQQQQHPL------ATTSPFLPAPVV----------YSP--ATGVVMKQG--YMTIPR 702
              :.::.|::.:.||      .:..|..|.|.:          ::|  |..:.:.:|  |:.:..
 Frog   174 FIRTERSQRRSRKPLPPPPPQESQKPLPPTPCLSLHKVVAMYDFTPLNAQDLPLHKGEEYVLLEE 238

  Fly   703 KPRAPSW--APSTSGAAGH--GSIQLSEFQSPTSPNP--SETGTATTAE--LQAEPVYDNLGLR- 758
            ....| |  |...:|..|:  |: .::|.|.|.....  |:..|.:.||  |:||.......:| 
 Frog   239 GTGNP-WLRARDKNGLEGYIPGN-YVTEAQDPLEIYEWYSKNMTRSQAEKLLRAEDKEGGFIVRD 301

  Fly   759 TTAGGNSTLNLTKIAGSQG---------GAGQQYSMRDRPLPATPSLTSVSSATNASKIYEPIHE 814
            ::..|..|:::...:..:|         ..|.||.:.::.|                  |..|.|
 Frog   302 SSKAGKYTVSVYAKSSGEGIIRHYVVCEAPGNQYYLAEKHL------------------YSSIPE 348

  Fly   815 LIQQQQQLQQQQQQQQQRLGSMDTEPLYGVRQQGITILPGSSISGAGLGHAAY 867
            ||       ...|.....|.|....|:..:|:        ::.|.||||:.::
 Frog   349 LI-------TYHQHNAAGLISRLKYPVCSLRK--------TAPSTAGLGYGSW 386

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek5NP_001245746.1 LRR_RI <76..160 CDD:238064
leucine-rich repeat 76..100 CDD:275380
LRR_8 99..159 CDD:290566
leucine-rich repeat 101..124 CDD:275380
LRR 122..145 CDD:197688
leucine-rich repeat 125..148 CDD:275380
LRR_8 148..207 CDD:290566
leucine-rich repeat 149..172 CDD:275380
leucine-rich repeat 173..196 CDD:275380
LRR_8 197..>229 CDD:290566
leucine-rich repeat 197..220 CDD:275380
LRRCT 229..277 CDD:214507
Ig 296..376 CDD:143165
btkNP_001123732.1 PH_Btk 8..167 CDD:269944 21/122 (17%)
SH3_BTK 209..264 CDD:212839 10/56 (18%)
SH2_Tec_Btk 267..370 CDD:198260 25/127 (20%)
PKc_like 388..638 CDD:419665
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E33208_3BAUD
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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