Protein Alignment kek5 and lingo1

DIOPT Version :9

• Sequence 1: NP_001245746.1
• Gene: kek5 / 32930
• FlyBaseID: FBgn0031016
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: NP_001093719.1
• Gene: lingo1 / 100101739
• XenbaseID: XB-GENE-921957
• Length: 606
• Species: Xenopus tropicalis
• Alignment Length: 520
• Identity: 103/520 - (19%)
• Similarity: 163/520 - (31%)
• Gaps: 195/520 - (37%)

  Fly    15 MILLLLGVL--VVLMALPPPTAGTTDWMQSCGTC--HCQWNSGKKSADCKNKALTKIPQDMSNEM 75
            |||.|...|  ::|:.:....:|      |...|  .|..:...:|..|..|....:|:.:..:.
 Frog     1 MILQLPSCLCPILLIVVGSILSG------SASGCPQRCDCSPQDRSVLCHRKRYLDVPEGIPTDT 59

  Fly    76 QVLDFAHNQIPELRREEFLLAGLPNVHKIFLRNCTIQEVHREAFKGLHILIELDLSGNRIRELHP 140
            ::||.:.|:|..|.::||  :..|.:.::.|....:..:...||.||..|..|.|..||::.:..
 Frog    60 RLLDLSKNRIKALNQDEF--SAFPYLEELELNENIVSIIEPGAFNGLFNLRSLGLRSNRLKLIPL 122

  Fly   141 GTFAGLEKLRNVIINNNEIEVLPNHLFVNLSFLSRIEFRNNRLRQVQLHVFAGTMALSAISLEQ- 204
            |.|.||..|..:.|:.|:|.:|.:.:|.:|..|..:|..:|.|..:....|.|..:|..::||:
 Frog   123 GVFTGLSNLTQLDISENKIVILLDDMFQDLYNLKSLEVGDNDLVYISHRAFRGLNSLEELTLEKC 187

  Fly   205 -------NRLSHLH----------------KETFKDLQKLMHLS--------------------- 225
                   ..|||||                ..:||.|.:|.:|.
 Frog   188 NLTSVPTEALSHLHGLITLKLRYLNINVIRDYSFKRLYRLKNLEIAHWPYLDTMTSNGLYGLNLT 252

  Fly   226 ----------------------------------------------------------------- 225
                                                                             
 Frog   253 SLSITHSNLSSIPYVAIRHLVYLRFLNLSYNPITAVEGSMLYELLRLQEFHLVGGQLSVVEPYAF 317

  Fly   226 ----------------------------------LQGNAWNCSCELQDFRDFAISKRLY-----T 251
                                              |..|...|.|.|     ..|.:|.:     .
 Frog   318 RGLNHLKVLNVSSNYLSTLEESSFHSVGNLETLILDKNPLACDCRL-----LWIFRRRWRLNFSR 377

  Fly   252 PPTDCQEPPQLRGKLWSEVPS----ENFAC-RPRILGSVRS--FIEANHDNISLPCRIVGSPRPN 309
            ....|..|..::||.:.:.|.    ..|.| |.||......  :::..| .:...||..|.|.|.
 Frog   378 QQPSCSSPEYVQGKEFKDFPDVLQPNYFTCRRARIQDHSAQVVYVDEGH-TVHFFCRADGDPPPT 441

  Fly   310 VTWVYNKRPLQQYDPRVRVLTS-----VEQMPEQPSQVLTSELRIVGVRASDKGAYTCVADNRGG 369
            :.|         ..||...:||     :...|:.     |.|:|...|:  |.|.|.|:|.|.||
 Frog   442 ILW---------QSPRKTFITSKSNGRLTVFPDG-----TLEVRYAQVQ--DNGTYHCIASNAGG 490

  Fly   370  369
             Frog   491  490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kek5	NP_001245746.1	LRR_RI	<76..160	CDD:238064	25/83 (30%)
		leucine-rich repeat	76..100	CDD:275380	7/23 (30%)
		LRR_8	99..159	CDD:290566	18/59 (31%)
		leucine-rich repeat	101..124	CDD:275380	5/22 (23%)
		LRR	122..145	CDD:197688	8/22 (36%)
		leucine-rich repeat	125..148	CDD:275380	9/22 (41%)
		LRR_8	148..207	CDD:290566	16/66 (24%)
		leucine-rich repeat	149..172	CDD:275380	7/22 (32%)
		leucine-rich repeat	173..196	CDD:275380	6/22 (27%)
		LRR_8	197..>229	CDD:290566	14/175 (8%)
		leucine-rich repeat	197..220	CDD:275380	11/46 (24%)
		LRRCT	229..277	CDD:214507	12/56 (21%)
		Ig	296..376	CDD:143165	23/79 (29%)
lingo1	NP_001093719.1	LRRNT	27..61	CDD:214470	6/33 (18%)
		LRR 1	58..79		7/22 (32%)
		leucine-rich repeat	59..82	CDD:275380	7/24 (29%)
		PLN00113	62..>381	CDD:215061	55/325 (17%)
		LRR 2	82..103		3/20 (15%)
		leucine-rich repeat	83..106	CDD:275380	5/22 (23%)
		LRR_8	106..165	CDD:338972	19/58 (33%)
		LRR 3	106..127		7/20 (35%)
		leucine-rich repeat	107..130	CDD:275380	9/22 (41%)
		LRR 4	130..151		6/20 (30%)
		leucine-rich repeat	131..154	CDD:275380	7/22 (32%)
		LRR 5	154..175		5/20 (25%)
		leucine-rich repeat	155..178	CDD:275380	6/22 (27%)
		LRR 6	178..199		4/20 (20%)
		leucine-rich repeat	179..250	CDD:275380	13/70 (19%)
		LRR 7	202..223		1/20 (5%)
		leucine-rich repeat	203..226	CDD:275380	3/22 (14%)
		LRR 8	250..271		0/20 (0%)
		leucine-rich repeat	251..274	CDD:275380	0/22 (0%)
		LRR 9	274..295		0/20 (0%)
		leucine-rich repeat	275..298	CDD:275380	0/22 (0%)
		LRR 10	298..319		0/20 (0%)
		leucine-rich repeat	299..322	CDD:275380	0/22 (0%)
		LRR 11	322..343		0/20 (0%)
		leucine-rich repeat	323..343	CDD:275380	0/19 (0%)
		Ig	425..500	CDD:386229	24/83 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	49	1.000	Domainoid score	I11593
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910