Protein Alignment HSD17B3 and spidey

DIOPT Version :9

• Sequence 1: NP_000188.1
• Gene: HSD17B3 / 3293
• HGNCID: 5212
• Length: 310
• Species: Homo sapiens
• Sequence 2: NP_572420.1
• Gene: spidey / 31703
• FlyBaseID: FBgn0029975
• Length: 321
• Species: Drosophila melanogaster
• Alignment Length: 245
• Identity: 109/245 - (44%)
• Similarity: 157/245 - (64%)
• Gaps: 11/245 - (4%)

Human    40 PKSF-----LRSMGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRS 99
            ||.|     |..||:|||:||:.|||||||:.|||:|||.:|||||:||||..:|.||....|..
  Fly    39 PKVFGSSVDLSKMGEWAVVTGSTDGIGKAYAKELARRGLKLVLISRSLEKLNVVAKEIGDKYGVE 103

Human   100 VKIIQADFT-KDDIYEHIKEKLAGLEIGILVNNVGMLPNLLPSHFLNA----PDEIQSLIHCNIT 159
            |::|..||| .|:||:.|:||..||.:|:||||||:... .|.:||:.    |..:::::..||.
  Fly   104 VRVIDVDFTGGDEIYDKIREKTTGLNVGVLVNNVGISYG-HPEYFLDCYKADPPFLRNIVAANIH 167

Human   160 SVVKMTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQ 224
            ||..||.|.|..|.|:::|:|:|:||...:.|.||.|:||::||||..||..||.|||...::||
  Fly   168 SVTHMTALFLPGMISQRRGVIINVSSTAGVIPNPLLSVYSSTKAFVNKFSDDLQTEYKEHGILIQ 232

Human   225 VLTPYAVSTAMTKYLNTNVITKTADEFVKESLNYVTIGGETCGCLAHEIL 274
            .:.|..|:|.|:|....:|...:.:.:|:.:|:.:.|..:|.|.|.|.:|
  Fly   233 SVQPGFVATNMSKIRKASVFAPSPETYVRSALSTLGIATQTAGYLPHALL 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HSD17B3	NP_000188.1	17beta-HSD1_like_SDR_c	48..284	CDD:187614	104/232 (45%)
spidey	NP_572420.1	PLN02780	8..321	CDD:166421	109/245 (44%)
		17beta-HSD1_like_SDR_c	52..288	CDD:187614	104/232 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0300
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D584062at33208
OrthoFinder	1	1.000	-	-		FOG0000465
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43899
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R721
SonicParanoid	1	1.000	-	-		X484
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.950