Protein Alignment nAChRalpha7 and htr3b

DIOPT Version :9

• Sequence 1: NP_001162795.1
• Gene: nAChRalpha7 / 32928
• FlyBaseID: FBgn0086778
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_021324909.1
• Gene: htr3b / 571632
• ZFINID: ZDB-GENE-071012-4
• Length: 369
• Species: Danio rerio
• Alignment Length: 331
• Identity: 104/331 - (31%)
• Similarity: 166/331 - (50%)
• Gaps: 17/331 - (5%)

  Fly    48 LLIMIPACAAGPHE------KRLLHALLDNYNSLERPVVNESDPLQLSFGLTLMQIIDVDEKNQL 106
            ||.:||.....|.:      .:|...||..||...|||.|.:.|..:...|.:..::|||.:.|.
Zfish    10 LLSVIPLAELVPEKPKRSALNQLTRLLLRKYNCGVRPVQNWTKPTTIYIDLIIQAVLDVDGQTQK 74

  Fly   107 LITNIWLKLEWNDMNLRWNSSEFGGVRDLRIPPHRLWKPDVLMYNSADEGFDGTYATNVVVRNNG 171
            :.|:||.:..|||..|.|:..||.|:.::.:....:|.||:::....|.| .......|.|..:|
Zfish    75 VTTSIWYRQIWNDEFLVWDPDEFDGITEISLSSDAIWVPDLIISEFVDVG-KSPVIPYVYVNCSG 138

  Fly   172 SCLYVPPGIFKSTCKIDITWFPFDDQRCEMKFGSWTYDGFQLDLQL---QDEAGGDISSFITNGE 233
            ......|....|.|.::|..||||.|.|.:.|.||.:...::||.|   .:|...|...|:.:||
Zfish   139 KVKNYKPIQVVSACHLEIYAFPFDKQNCTLTFRSWLHSVSEVDLALWRPAEEIANDTREFMNDGE 203

  Fly   234 WDLLGVPGKRNEIYY--NCCPEPYIDITFAILIRRKTLYYFFNLIVPCVLIASMALLGFTLPPDS 296
            |:|||||.:    |:  |.....|..|.|.:||||:.|.|...|::|.:.:..:.::.|.|||:|
Zfish   204 WELLGVPSR----YWTLNLEDRDYAQIQFNVLIRRRPLLYVVGLLIPSIFLMVVDVISFYLPPNS 264

  Fly   297 GEKLSLGVTILLSLTVFLNMVAETMPATSDAVPLLGTYFN-CIMFMVASSVVSTILILNYHHRNP 360
            |.:::...:|||..||....:.:.:|||:...||:|.:|. |:..::.|..:|..::...|:...
Zfish   265 GTRITFKTSILLGYTVIRVNLMDEIPATAIKTPLIGVFFAICMALLLLSLAMSIFVVKLLHYSEK 329

  Fly   361 DTHEMS 366
            :..|||
Zfish   330 EVKEMS 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRalpha7	NP_001162795.1	LIC	59..548	CDD:273305	100/320 (31%)
		Neur_chan_LBD	61..268	CDD:280998	70/217 (32%)
		Neur_chan_memb	275..552	CDD:280999	27/93 (29%)
htr3b	XP_021324909.1	Neur_chan_LBD	26..>325	CDD:332142	95/303 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910