Protein Alignment out and SLC16A3

DIOPT Version :9

• Sequence 1: NP_001285435.1
• Gene: out / 32926
• FlyBaseID: FBgn0259834
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_001035887.1
• Gene: SLC16A3 / 9123
• HGNCID: 10924
• Length: 465
• Species: Homo sapiens
• Alignment Length: 620
• Identity: 114/620 - (18%)
• Similarity: 188/620 - (30%)
• Gaps: 238/620 - (38%)

  Fly    31 DLGPDFV-APDGGWGWVVCLAAGLNNFFLFPALQQYGLIYRVRMQSLGFDAKQTTTIVNVVMAIS 94
            |.||..| ||||||||.|.....:...|.:...:...:.::..:|..|.....|..|.::::|:.
Human     7 DEGPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLAML 71

  Fly    95 SLVGIVNGAMFRRFTFRQVALTGTSLAFLGVFLSAFCTTFWQYIICLSAIFGIGLGLAMAATSLA 159
            ...|.:......||..|.|.|.|...|.||:..::||.:..|..:....|.|:||.|....:.:.
Human    72 YGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPSLIM 136

  Fly   160 VNTYFKLKRRRATGFSWTITGLGPIFFPQVS---TVLLGYYGAQGTILIYAGIAMNAILCALTLQ 221
            :|.||..:|..|.|.:   ....|:|...:|   .:|...||.:|..||..|:.:|..:||..::
Human   137 LNRYFSKRRPMANGLA---AAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVCAALMR 198

  Fly   222 PVLWHVKKPEKPVHNTIEGIAETEKLQPELLEANGNLLSPSNDPWKDYECKYCQYQKRSKRGLFS 286
            |::
Human   199 PLV-------------------------------------------------------------- 201

  Fly   287 SQYLFNVDDPERPGYEIT-EPGTPMLARANDGWFGSKLSLTSESAGGARSRTRQALMRQVSSRSR 350
                            :| :||:
Human   202 ----------------VTAQPGS------------------------------------------ 208

  Fly   351 ENLDRLEQNRHDQGPDTPSAAALYKPNYFNREREDLDRYASKTSVYSRPGQDELLRCTCAEDKAL 415
                         ||..||
Human   209 -------------GPPRPS---------------------------------------------- 214

  Fly   416 LQKTAESLQVNLFNNSADNTEAEEEAKRRMTFFQKVSKFFDLDLLRDFTFVNLAVGMSIMMFGEM 480
                                       ||:         .||.:.||..||..||..|:|:.|..
Human   215 ---------------------------RRL---------LDLSVFRDRGFVLYAVAASVMVLGLF 243

  Fly   481 NFSVLTPFILNSFGYTDTQISLVMSLLACMDISVR----FLAPLALEKVKLDNRVLFAFGILCIA 541
            ...|.........|..||:.:.::::|..:||..|    |:|  .|.||:..:..||:|.:....
Human   244 VPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVA--GLGKVRPYSVYLFSFSMFFNG 306

  Fly   542 VGRVVVAFTDSYE--IMIGVFLLIGFGKAFRTIFSPLIIPSYVPLNRLPAASGLQLIFNTIFSFA 604
            :..:..:....|.  ::..:|..|.:|......|.  ::.:.|..::..:|.||.|:...: :..
Human   307 LADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFE--VLMAIVGTHKFSSAIGLVLLMEAV-AVL 368

  Fly   605 MGPILG--IL--TEAYGYAATIHTINALTLLALLL 635
            :||..|  :|  |..|.|...:.....||...:||
Human   369 VGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILL 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
out	NP_001285435.1	MFS	45..>225	CDD:119392	46/182 (25%)
		MFS	<464..621	CDD:119392	40/166 (24%)
		MFS_1	468..>621	CDD:284993	38/162 (23%)
SLC16A3	NP_001035887.1	2A0111	8..444	CDD:331689	113/619 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	419..438

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145515
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.950