Protein Alignment out and SLC16A6

DIOPT Version :9

• Sequence 1: NP_001285435.1
• Gene: out / 32926
• FlyBaseID: FBgn0259834
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: XP_005257846.2
• Gene: SLC16A6 / 9120
• HGNCID: 10927
• Length: 527
• Species: Homo sapiens
• Alignment Length: 613
• Identity: 100/613 - (16%)
• Similarity: 200/613 - (32%)
• Gaps: 177/613 - (28%)

  Fly    39 PDGGWGWVVCLAAGLNNFFLFPALQQYGLIYRVRMQSLGFDAKQTTTIVNVVMAISSLVGIVNGA 103
            |||||||.|.::......|.:..::.:|:.:...|.|......:.:.|:::.:.:.:....:...
Human    23 PDGGWGWAVAVSFFFVEVFTYGIIKTFGVFFNDLMDSFNESNSRISWIISICVFVLTFSAPLATV 87

  Fly   104 MFRRFTFRQVALTGTSLAFLGVFLSAFCTTFWQYIICLSAIFGIGLGLAMAATSLAVNTYFKLKR 168
            :..||..|.|.:.|..|...|:..::|........:.:..|.|:|...:...|...::.||..:|
Human    88 LSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMYVAIGIISGLGYCFSFLPTVTILSQYFGKRR 152

  Fly   169 RRATGFSWTITGLGPIFFPQVSTVLLGYYGAQGTILIYAGIAMNAILCALTLQPVLWHVKKPEKP 233
            ...|..:.|........|......|....|.:.::|....:.:|.::....|:|:.  ::.|..|
Human   153 SIVTAVASTGECFAVFAFAPAIMALKERIGWRYSLLFVGLLQLNIVIFGALLRPIF--IRGPASP 215

  Fly   234 VHNTIEGIAETEKLQPELLEANGNLLSPSNDPWKDYECKYCQYQKRSKRGLFSSQYLFNVDDPER 298
                        |:   :::.|..            |.:|....::::..:.|      :|.
Human   216 ------------KI---VIQENRK------------EAQYMLENEKTRTSIDS------IDS--- 244

  Fly   299 PGYEITEPGTPMLARANDGWFGSKLSLTSESAGGARSRTRQALMRQVSSRSRENLDRLEQNRHDQ 363
             |.|:|                                           .|.:|:
Human   245 -GVELT-------------------------------------------TSPKNV---------- 255

  Fly   364 GPDTPSAAALYKPNYFNRERE---DLDRYASKTSVYSRPGQDELLRCTCAEDKALLQKTAESLQV 425
                        |.:.|.|.|   |:.:...|||  .||          :|.||.|
Human   256 ------------PTHTNLELEPKADMQQVLVKTS--PRP----------SEKKAPL--------- 287

  Fly   426 NLFNNSADNTEAEEEAKRRMTFFQKVSKFFDLDLLRDFTFVNLAVGMSIMMFGEMNFSVLTPFIL 490
                                         .|..:|::.:|:..|:   ..:|..:.|...:.:|:
Human   288 -----------------------------LDFSILKEKSFICYAL---FGLFATLGFFAPSLYII 320

  Fly   491 N---SFGYTDTQISLVMSLLACMDISVRFLAPLALEKVKLDNRVLFAFGILCIAVGRVVVAFTDS 552
            .   |.|....:.:.::|.:|..::..|..|...|.:..:....:....::.:.|......|...
Human   321 PLGISLGIDQDRAAFLLSTMAIAEVFGRIGAGFVLNREPIRKIYIELICVILLTVSLFAFTFATE 385

  Fly   553 YEIMIGVFLLIGF--GKAFRTIFSPLIIPSYVPLNRLPAASGLQLIFNTIFSFAMGPILGILTEA 615
            :..::...:..||  |....|....|.....|.:.::.:|:|:.:...:|...|..|:.|:|.:.
Human   386 FWGLMSCSIFFGFMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYIFIQSIAGLAGPPLAGLLVDQ 450

  Fly   616 --------YGYAATIHTINALTLLALLL 635
                    |..||.:    ||..:.|.|
Human   451 SKIYSRAFYSCAAGM----ALAAVCLAL 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
out	NP_001285435.1	MFS	45..>225	CDD:119392	31/179 (17%)
		MFS	<464..621	CDD:119392	29/169 (17%)
		MFS_1	468..>621	CDD:284993	28/165 (17%)
SLC16A6	XP_005257846.2	2A0113	23..512	CDD:273325	100/613 (16%)
		MFS	33..476	CDD:119392	92/603 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145506
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.740