DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment out and MCH5

DIOPT Version :9

Sequence 1:	NP_001285435.1	Gene:	out / 32926	FlyBaseID:	FBgn0259834	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	NP_014951.4	Gene:	MCH5 / 854483	SGDID:	S000005833	Length:	521	Species:	Saccharomyces cerevisiae

Alignment Length:	179	Identity:	46/179 - (25%)
Similarity:	81/179 - (45%)	Gaps:	13/179 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 NDTTKPKKPKRRDKSDLGPDFVAPDGGW-GWVVCLAAGLNNFFLFPALQQYGLIYRVRMQSLGFD 79
            |.::.....|..|.::....|  |:||: .|||.....|.....|..|...|:| ...:|.....
Yeast    79 NTSSTHDSDKEEDSNEEIESF--PEGGFKAWVVTFGCFLGLIACFGLLNSTGVI-ESHLQDNQLS 140

  Fly    80 AKQTTTI---VNVVMAISSLVGIVNGAMFRRFTFRQVALTGTSLAFLGVFLSAFCTTFWQYIICL 141
            ::..:||   .::.:.:.|...|::|..|.|..||.:.:.||.....|:|.:|..|.:|.:|:..
Yeast   141 SESVSTIGWLFSLFLFVCSASCIISGTYFDRNGFRTIMIVGTVFHVAGLFATANSTKYWHFILSF 205

  Fly   142 SAIFGIGLGLAMA-ATSLAVNTYFKLKRRRATGFSWTITG--LGPIFFP 187
            :.:.|.|.|:.:: ..|:..:.:||   ||.|..:....|  :|.:.||
Yeast   206 AIVCGFGNGIVLSPLVSVPAHYFFK---RRGTALAMATIGGSVGGVVFP 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
out	NP_001285435.1	MFS	45..>225	CDD:119392	39/149 (26%)
		MFS	<464..621	CDD:119392
		MFS_1	468..>621	CDD:284993
MCH5	NP_014951.4	MFS_MCT_SLC16	106..510	CDD:340910	39/150 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343221
Domainoid	1	1.000	56	1.000	Domainoid score	I2686
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.800