DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment out and MCH4

DIOPT Version :9

Sequence 1:	NP_001285435.1	Gene:	out / 32926	FlyBaseID:	FBgn0259834	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	NP_014522.1	Gene:	MCH4 / 854030	SGDID:	S000005479	Length:	501	Species:	Saccharomyces cerevisiae

Alignment Length:	251	Identity:	71/251 - (28%)
Similarity:	107/251 - (42%)	Gaps:	15/251 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SLTEKNHTQVYNDTTKPKKPKRR----DKSDL--GPDFVAPDGGW-GWVVCLAAGLNNFFLFPAL 62
            ::.:||..||..|..|......|    .::.|  ..|...||||. .|:|...|.:....:|..:
Yeast    50 AILKKNSDQVDLDVNKLTNVTSRVLNTPEASLIYDDDREFPDGGLKAWLVVFGAFMGLVPVFGLI 114

  Fly    63 QQYGLI--YRVRMQSLGFDAKQTTTIVNVVMAISSLVGIVNGAMFRRFTFRQVALTGTSLAFLGV 125
            ...|.|  |..:.|.....:...:.|.::.:|||.|..|::|..|.|.....:..|||.:...|:
Yeast   115 NSLGAIESYISKHQLANISSSTISWIFSLYLAISFLSCILSGGYFDRNGSIGLMCTGTVIYAGGL 179

  Fly   126 FLSAFCTTFWQYIICLSAIFGIGLGLAMAATSLAVNTYFKLKRRRATGFSWTITGLGPIFFPQVS 190
            |..|.|.:.||:|:..|...|:|.|:.|......|.|:|..:|..||..|.....:|.|.||.:.
Yeast   180 FALANCKSVWQFILAFSVCSGLGTGILMTPLIGTVATWFLKRRGIATSISTMGGSIGGIVFPIML 244

  Fly   191 TVLLGYYGAQGTILIYAGIAMNAILCALTLQPVLWHVKKPEKPVHNTIEGIAETEK 246
            ..|....|.|..|.|.:.|.:..::||..|      .::..|||....:..||..|
Yeast   245 RKLYKEVGFQWAIRILSFICLTCLICASVL------ARERTKPVVQPFKSKAEVAK 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
out	NP_001285435.1	MFS	45..>225	CDD:119392	52/181 (29%)
		MFS	<464..621	CDD:119392
		MFS_1	468..>621	CDD:284993
MCH4	NP_014522.1	MFS_MCT_SLC16	96..490	CDD:340910	58/205 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343224
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.800