Protein Alignment out and MCH2

DIOPT Version :9

• Sequence 1: NP_001285435.1
• Gene: out / 32926
• FlyBaseID: FBgn0259834
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_012701.2
• Gene: MCH2 / 853659
• SGDID: S000001704
• Length: 473
• Species: Saccharomyces cerevisiae
• Alignment Length: 708
• Identity: 123/708 - (17%)
• Similarity: 196/708 - (27%)
• Gaps: 348/708 - (49%)

  Fly     6 LTEKNHTQVYNDTTKPKKPKRRDKSDLGPD----FVAPDGGWGWVVCLAAGLNNFFLFPALQQYG 66
            ::|:.|...:.|.  ..|.....|.|:..:    ...||||:||.:.||..|.||..:.|...|.
Yeast     1 MSEERHEDHHRDV--ENKLNLNGKDDINGNTSISIEVPDGGYGWFILLAFILYNFSTWGANSGYA 63

  Fly    67 LIY--------------RVRMQSLG--------FDAKQTTTIVNVVMAISSLVGIVNGAMFRRFT 109
             ||              ::...|:|        |.|...|.:.: :.:|..::|:  |.:|:
Yeast    64 -IYLAHYLENNTFAGGSKLDYASIGGLAFSCGLFFAPVITWLYH-IFSIQFIIGL--GILFQ--- 121

  Fly   110 FRQVALTGTSLAFLGVFLSAFCTTFWQYIICLSAIFGIGLGLAMAATSLAVNTYFKLKRRRATGF 174
                   |.:|     .|:||..|.|:..:....:.|.||......:...:..:|:.||..|:|.
Yeast   122 -------GAAL-----LLAAFSVTLWEIYLTQGVLIGFGLAFIFIPSVTLIPLWFRNKRSLASGI 174

  Fly   175 SWTITGLGPIFFPQVSTVLLGYYGAQGTILIYAGIAMNAILCALTLQPVLWHVKKPEKPVHNTIE 239
            ....:|||.|.|                     .:.|.:||
Yeast   175 GTAGSGLGGIVF---------------------NLGMQSIL------------------------ 194

  Fly   240 GIAETEKLQPELLEANGNLLSPSNDPWKDYECKYCQYQKRSKRGLFSSQYLFNVDDPERPGYEIT 304
                                                    .|||:
Yeast   195 ----------------------------------------QKRGV-------------------- 199

  Fly   305 EPGTPMLARANDGWFGSKLSLTSESAGGARSRTRQALMRQVSSRSRENLDRLEQNRHDQGPDTPS 369
                                             :.||:.|
Yeast   200 ---------------------------------KWALIAQ------------------------- 206

  Fly   370 AAALYKPNYFNREREDLDRYASKTSVYSRPGQDELLRCTCAEDKALL--QKTAESLQVNLFNNSA 432
                                              .:.||.....||:  :.|.:.|:
Yeast   207 ----------------------------------CIICTSLSTIALMLTRTTHQGLR-------- 229

  Fly   433 DNTEAEEEAKRRMTFFQKVSKFFDLDLLRDFT------FVNLA-VGMSIMMFGEMNFSVLTPFIL 490
                   :.||...|     :..|.|:|.:|.      ||:.| :|..::::...:|:|
Yeast   230 -------QHKRSYKF-----ELLDYDVLSNFAVWLLFGFVSFAMLGYVVLLYSLSDFTV------ 276

  Fly   491 NSFGYTDTQISLVMSLLACMDISVRFLAPLALEKVKLDNRVLFAFGILCIAVGRVVVA-FTDSY- 553
             |.|||..|.|.|    :|| :||..|                        :||.:|. ..|.|
Yeast   277 -SLGYTSKQGSYV----SCM-VSVGSL------------------------LGRPIVGHIADKYG 311

  Fly   554 EIMIGVF--------------------------LLIG--FGKAFRTIFSPLIIPSYVPLNRLPAA 590
            .:.:|:.                          ||:|  .|..:.||.|  |:...|.|.:||..
Yeast   312 SLTVGMILHLVMAILCWAMWIPCKNLATAIAFGLLVGSIMGTIWPTIAS--IVTRIVGLQKLPGT 374

  Fly   591 SGLQLIFNTIFSFAMGPILGI---LTEAYG---YAATIHTINALTLLALLLWLAESVV 642
            .|...||...|:. :.||:|:   .|:..|   |...|....|...::|..||....:
Yeast   375 FGSTWIFMAAFAL-VAPIIGLELRSTDTNGNDYYRTAIFVGFAYFGVSLCQWLLRGFI 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
out	NP_001285435.1	MFS	45..>225	CDD:119392	42/201 (21%)
		MFS	<464..621	CDD:119392	46/199 (23%)
		MFS_1	468..>621	CDD:284993	44/189 (23%)
MCH2	NP_012701.2	MFS_MCT_SLC16	41..428	CDD:340910	113/661 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
TreeFam	0	0.000	Not matched by this tool.
	4	3.910