DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment out and ATG22

DIOPT Version :9

Sequence 1:NP_001285435.1 Gene:out / 32926 FlyBaseID:FBgn0259834 Length:655 Species:Drosophila melanogaster
Sequence 2:NP_009892.1 Gene:ATG22 / 850319 SGDID:S000000543 Length:528 Species:Saccharomyces cerevisiae


Alignment Length:270 Identity:52/270 - (19%)
Similarity:94/270 - (34%) Gaps:97/270 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly    43 WGWVVCLAAGLNNFFLFPALQQYGLIYRVRMQSLG-FDAKQTTTIVN------------------ 88
            :|||          .||.:.:...|:..|.:..:. |....:.|.:|                  
Yeast   301 YGWV----------SLFESFKHARLLKDVMIFLIAWFIISDSITTINSTAVLFSKAELHMSTLNL 355

  Fly    89 VVMAISSLVGIVNGA-MFRRF-----------TFRQVALTGTSLAF---LGVFLSAFCTTFWQYI 138
            :::::.::|..:.|| |..:|           |...:.:..:.:.|   ||.|.:||.......:
Yeast   356 IMISVLTVVNAMLGAFMIPQFLATKFRWTSSQTLMYIIIWASFIPFYGILGFFFNAFGLKHKFEM 420

  Fly   139 ICLSAIFGIGLGLAMAATSLAV----------NTYFKLKRRRATGFSWTITG---LGP----IFF 186
            ..|:..:|:.|| .::|.|.:|          :|:|.:       ||.|..|   |||    :..
Yeast   421 FLLAIWYGLSLG-GLSAVSRSVFSLIVPPGKESTFFSM-------FSITDKGSSILGPFLVGLLT 477

  Fly   187 PQVSTVLLGYYGAQGTILIYAGIAMNAILCALTLQPVLWHVKKPEKPVHNTIE---GIAETEKLQ 248
            .:...:...:|             ...:|..|:|            ||.|.::   |..|.|:|.
Yeast   478 DKTHNIRYSFY-------------FFFLLLMLSL------------PVLNCLDVKRGRREAEELS 517

  Fly   249 PELLEANGNL 258
            ..|.|:...|
Yeast   518 QVLPESERRL 527

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
outNP_001285435.1 MFS 45..>225 CDD:119392 41/230 (18%)
MFS <464..621 CDD:119392
MFS_1 468..>621 CDD:284993
ATG22NP_009892.1 MFS_Atg22_like 28..484 CDD:341036 38/200 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11360
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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