Protein Alignment out and Slc16a14

DIOPT Version :10

• Sequence 1: NP_573378.1
• Gene: out / 32926
• FlyBaseID: FBgn0259834
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_082197.1
• Gene: Slc16a14 / 71781
• MGIID: 1919031
• Length: 512
• Species: Mus musculus
• Alignment Length: 600
• Identity: 127/600 - (21%)
• Similarity: 213/600 - (35%)
• Gaps: 157/600 - (26%)

  Fly    10 NHTQVYNDTTKPKKPKRRDKSDLGPDFVAPDGGWGWVVCLAAGLNNFFLFPALQQYGLIYRVRMQ 74
            :|..:..|....:|.|.:......||.   ||||.|::.|::...:..:..:....|::....::
Mouse     4 SHEDIGYDLEDDRKAKNKKTLKPHPDI---DGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLE 65

  Fly    75 SLGFDAKQTTTIVNVVMAISSLVGIVNGAMFRRFTFRQVALTGTSLAFLGVFLSAFCTTFWQYII 139
            ........|..:.::.|.|:.:||...|........||.|:.|..:..||..|||:........|
Mouse    66 EFHQSRGLTAWVSSLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVQSLFI 130

  Fly   140 CLSAIFGIGLGLAMAATSLAVNTYFKLKRRRATGFSWTITGLGPIFFPQVSTVLLGY----YGAQ 200
            ......|:|.|:|.....:.|..||:.:|..|.|.|.|.||.|..    :.||||.|    ||.:
Mouse   131 TFGVAAGLGSGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTF----LMTVLLKYLCAEYGWR 191

  Fly   201 GTILIYAGIAMNAILCALTLQPVLWHVKKPEKPVHNTIEGIAETEK------LQPELLEANGNL- 258
            ..:.|...:::|..:|...::|:     .|||     :|...|.|:      ...|.:::.|.|
Mouse   192 NAMFIQGALSLNLCVCGALMRPL-----SPEK-----LENCPEAEEPCALPAYSTESVKSGGPLG 246

  Fly   259 ------LSPSNDPWK-DYECKYCQYQKRSKRGLFSSQYLFNVDD---PERPGYEITEPGTPMLAR 313
                  ..|.|:... |.:.:.||.|...::.:.:.:.|..|..   ..|.|:.          .
Mouse   247 MAEEQDRRPGNEEMVCDLQTQECQGQTHPRKNVCAFRVLKTVSQLTVQVRRGFR----------D 301

  Fly   314 ANDGWFGSKLSLTSES-------AGGARSRTRQALMRQVSSRSRENLDRLEQNRHDQGPDTPSAA 371
            .:.|:||:....|:..       |..|.|......:......|..||.  |||  |..|.|...|
Mouse   302 WHSGYFGTASLFTNRMFVAFIFWALFAYSSFVIPFIHLPEIVSLYNLS--EQN--DTFPLTSIIA 362

  Fly   372 ALYKPNYFNREREDLDRYASKTSVYSRPGQDELLRCTCAEDKALLQKTAESLQVNLFNNSADNTE 436
            .|:                    ::.               |.:|...|:...::::|
Mouse   363 ILH--------------------IFG---------------KVILGAVADLPCISVWN------- 385

  Fly   437 AEEEAKRRMTF----FQKVSKFFDLDLLRDFTFVNLAVGMSIMMFGEMNFSVL---------TPF 488
                     .|    |..|...|.|.|:.  |:.:|||..:::.|....||::         |..
Mouse   386 ---------VFLIANFTLVLSIFLLPLMH--TYASLAVICALIGFSSGYFSLMPVVTEDLVGTEH 439

  Fly   489 ILNSFGYTDTQISLVMSLLACMD-ISVRFLAPLALEKVKLDNRVLFAF---GILCIAVGRVVVAF 549
            :.|::|           ::.|.: ||.....|.|.....:..:..|:|   |:|
Mouse   440 LANAYG-----------IIICANGISALLGPPFAGWIFDITQKYDFSFYICGLL----------- 482

  Fly   550 TDSYEIMIGV-FLLI 563
                 .|:|: ||||
Mouse   483 -----YMVGILFLLI 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
out	NP_573378.1	MFS	44..>221	CDD:475125	44/180 (24%)
		MFS	<459..626	CDD:475125	25/118 (21%)
Slc16a14	NP_082197.1	MFS_MCT14	35..494	CDD:340987	116/565 (21%)