DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment out and slc16a7

DIOPT Version :9

Sequence 1:	NP_001285435.1	Gene:	out / 32926	FlyBaseID:	FBgn0259834	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	NP_001032485.1	Gene:	slc16a7 / 641419	ZFINID:	ZDB-GENE-051113-248	Length:	465	Species:	Danio rerio

Alignment Length:	343	Identity:	64/343 - (18%)
Similarity:	127/343 - (37%)	Gaps:	89/343 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 SDLGPDFVAPDGGWGWVVCLAAGLNNFFLFPALQQYGLIYRVRMQSLGFDAKQTTTIVNVVMAIS 94
            ::||  :..|||||||.|...:.::..|.:...:...:.::...:.......|...:.::::|..
Zfish     7 TNLG--YTPPDGGWGWAVVFGSFISIGFSYAFPKSLTIYFKEIQEYFSISYSQIAWVSSIMLATM 69

  Fly    95 SLVGIVNGAMFRRFTFRQVALTGTSLAFLGVFLSAFCTTFWQYIICLSAIFGIGLGLAMAATSLA 159
            ...|.|:..:..|:..|.|.:.|..:..:.:..::|.|:.....:|:..|.|.||...:......
Zfish    70 YAGGPVSSILVNRYGSRPVVIAGGLMVGVAMVTASFGTSILHLYLCVGVIGGFGLAFDLQPALTI 134

  Fly   160 VNTYFKLKRRRATGFSWTITGLGPIFFPQVSTV---LLGYYGAQGTILIYAGIAMNAILCALTLQ 221
            :..||.:||..|.|.:  :.| .|:|...::.|   |...:|.:|:..|..|:..|..:....::
Zfish   135 IGKYFLVKRPMANGIA--MAG-SPVFLSTLAPVNQFLFDQFGWRGSFFILGGVLFNCCVAGSLMR 196

  Fly   222 PVLWHVKKPEKPVHNTIEGIAETEKLQPE------------------------------LLEANG 256
            |:       :.||..|.|     :.:.|:                              |:...|
Zfish   197 PI-------KIPVSKTTE-----DNISPQTAGQDDSKPSGCSSKLNQFIDISLFKHRGFLIYLVG 249

  Fly   257 NL------------LSPSNDPWKDYECKYCQYQKRSKRGLFSSQYLFNVDDPERPGYEITE---- 305
            |:            |:|              |.|......:|:.:|.::       :.:.:
Zfish   250 NVLMFFGFFAPVVFLAP--------------YAKHQGVDEYSAAFLLSI-------FALVDMFAR 293

  Fly   306 PGTPMLARANDGWFGSKL 323
            |||.::  ||..|...|:
Zfish   294 PGTGLV--ANTKWIRPKI 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
out	NP_001285435.1	MFS	45..>225	CDD:119392	35/182 (19%)
		MFS	<464..621	CDD:119392
		MFS_1	468..>621	CDD:284993
slc16a7	NP_001032485.1	2A0113	1..440	CDD:273325	64/343 (19%)
slc16a7	NP_001032485.1	MFS	20..420	CDD:119392	56/328 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578796
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.750