Protein Alignment out and slc16a1

DIOPT Version :10

• Sequence 1: NP_573378.1
• Gene: out / 32926
• FlyBaseID: FBgn0259834
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_001015931.1
• Gene: slc16a1 / 548685
• XenbaseID: XB-GENE-1014566
• Length: 490
• Species: Xenopus tropicalis
• Alignment Length: 635
• Identity: 121/635 - (19%)
• Similarity: 214/635 - (33%)
• Gaps: 206/635 - (32%)

  Fly    33 GP-DFVAPDGGWGWVVCLAAGLNNFFLFPALQQYGLIYRVRMQSLGFDAKQTTTIVNVVMAISSL 96
            || .:..|:|||||||.:||.::..|.:...:...:.::......|..:.:.:.|.::::|:...
 Frog     7 GPVGYTPPEGGWGWVVVVAAFVSIGFSYAFPKSITVFFKDIEAIFGATSSEVSWISSIMLAVMYA 71

  Fly    97 VGIVNGAMFRRFTFRQVALTGTSLAFLGVFLSAFCTTFWQYIICLSAIFGIGLGLAMAATSLAVN 161
            .|.::..:..::..|.|.:.|..||..|:..::||.|..:..:|:..:.|.||...:......:.
 Frog    72 GGPISSVLVNKYGSRPVMIAGGCLAGTGLIAASFCNTVAELYLCIGVVGGFGLAFNLNPALTMIG 136

  Fly   162 TYFKLKRRRATGFSWTITGLGPIFFPQVSTVLLGYY---GAQGTILIYAGIAMNAILCALTLQPV 223
            .||..||..|.|.:  :.| .|:|...::.:...:|   |.:|:.||..|:..|..:....::|:
 Frog   137 KYFFKKRPIANGLA--MAG-SPVFLSTLAPLNQYFYSIFGWRGSFLILGGLLFNCCVAGSLMRPI 198

  Fly   224 LWHVKKPEKPVHNTIEGIAETEKLQPELLEANGNLLSPSNDPWKDYECKYCQYQKRSKRGLFSSQ 288
               ..|||.          ..:|:..|:||..|..:|
 Frog   199 ---GPKPED----------TKKKVTKEVLEEAGKCVS---------------------------- 222

  Fly   289 YLFNVDDPERPGYEITEPGTPMLARANDGWFGSKLSLTSESAGGARSRTRQALMRQVSSRSRENL 353
                                                                             
 Frog   223 ----------------------------------------------------------------- 222

  Fly   354 DRLEQNRHDQGPDTPSAAALYKPNYFNREREDLDRYASKTSVYSRPGQDELLRCTCAEDKALLQK 418
                                         :||.|.:                       |.|:
 Frog   223 -----------------------------KEDGDAH-----------------------KDLI-- 233

  Fly   419 TAESLQVNLFNNSADNTEAEEEAKRRMTFFQKVSKFFDLDLLRDFTFVNLAVGMSIMMFGEMNFS 483
                               |.:||.:.|.||.::||.||.|.....|:....|..||.||
 Frog   234 -------------------EGKAKTKPTLFQTINKFLDLSLFTHRGFLLYLSGHMIMFFG----- 274

  Fly   484 VLTPFIL-----NSFGYTDTQISLVMSLLACMDISVR-FLAPLALEK-VKLDNRVLFAFGILCIA 541
            :..|.:.     .|...:....:.::|:||.:|:..| .:..:|..| |:...:..||..:|...
 Frog   275 LFAPLVFLSNYAKSKNISPESAAFLLSILAIVDMIARPSMGIVANTKWVRPKIQYFFAVAVLYNG 339

  Fly   542 VGRVVVAFTDSYEIMIGVFLLIG-FGKAFRTIFSPLI--IPSYVPLNRLPAASGLQLIFNTIFSF 603
            :..::|..:.||   :|..:..| ||.||..:.|.|.  :...|...|..:|.||..|.......
 Frog   340 ICHLLVPLSTSY---VGFCIYAGFFGFAFGWLSSVLFETLMDLVGAQRFSSAVGLVTIVECCPVL 401

  Fly   604 AMGPILGILTEAYG-YAATIHTINALTLLA-LLLWLAESVVRRILGIPSK 651
            ...|:||.|.:.|| |..|......:.::| :.|::..::..|:|....|
 Frog   402 LGPPLLGRLNDIYGDYKYTYQACGIVLIVASVYLFIGMTIHYRLLAKEQK 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
out	NP_573378.1	MFS	44..>221	CDD:475125	40/179 (22%)
		MFS	<459..626	CDD:475125	45/177 (25%)
slc16a1	NP_001015931.1	2A0113	6..471	CDD:273325	121/635 (19%)