DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment out and kar

DIOPT Version :9

Sequence 1:	NP_001285435.1	Gene:	out / 32926	FlyBaseID:	FBgn0259834	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	NP_001189213.1	Gene:	kar / 45883	FlyBaseID:	FBgn0001296	Length:	612	Species:	Drosophila melanogaster

Alignment Length:	240	Identity:	63/240 - (26%)
Similarity:	103/240 - (42%)	Gaps:	30/240 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 DTTKPKKPKRRDKSDLGPDFV------------APDGG-WGWVVCLAAGLNNFFLFPALQQYGLI 68
            |..||..|.:....:.....:            .|||| ..|:|.::|.|.|..:|..:..||:|
  Fly    40 DAMKPSAPVQNGNGNANGTHIEAPCCRDIHGKEPPDGGARAWLVMVSAFLCNGIIFGFINTYGVI 104

  Fly    69 YRV---RMQSLGFDAKQTTTIVNVVMAISS--LVGIVNGAMFRRFTFRQVALTGTSLAFLGVFLS 128
            :.:   |:..||.....:...:...:||.:  |...:.|.:..:...|.....|..|:..|:.||
  Fly   105 HSLLTDRLTKLGDPEASSKAALIGALAIGTTFLFSTMAGCLTDKIGLRLTTFAGGVLSAGGLLLS 169

  Fly   129 AFCT-----TFWQYIICLSAIFGIGLGLAMAATSLAVNTYFKLKRRRATGFSWTITGLGPIFFPQ 188
            :|||     .::.|.|    :||:|..||...|...:..|||....:.:||....:.:..:..|.
  Fly   170 SFCTENIGALYFTYGI----MFGLGAALAYTPTLAILGHYFKRYLGKVSGFVTAGSSVFTVILPP 230

  Fly   189 VSTVLLGYYGAQGTILIYAGIAMNAILCALTLQPVLWHVKKPEKP 233
            ....|||.||.:||:.|.:.::...|||:...:|:  | ..||.|
  Fly   231 CLDKLLGSYGLEGTLRIMSLVSAFIILCSFVYKPL--H-PPPEPP 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
out	NP_001285435.1	MFS	45..>225	CDD:119392	51/189 (27%)
		MFS	<464..621	CDD:119392
		MFS_1	468..>621	CDD:284993
kar	NP_001189213.1	MFS	81..459	CDD:119392	55/199 (28%)
kar	NP_001189213.1	MFS_1	124..439	CDD:284993	43/156 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.891027	Normalized mean entropy	S3509
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.870