Protein Alignment out and slc16a12b

DIOPT Version :9

• Sequence 1: NP_001285435.1
• Gene: out / 32926
• FlyBaseID: FBgn0259834
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_001139286.1
• Gene: slc16a12b / 449947
• ZFINID: ZDB-GENE-050522-80
• Length: 488
• Species: Danio rerio
• Alignment Length: 630
• Identity: 116/630 - (18%)
• Similarity: 196/630 - (31%)
• Gaps: 233/630 - (36%)

  Fly    39 PDGGWGWVVCLAAGLNNFFLFP----ALQQYGLIYRVRMQ-SLGFDAKQTTTIVNVVMAISSLVG 98
            |||||||::  .||.   |:..    |:.:...|:.|..| ....|...|..|.::|...:.|..
Zfish    24 PDGGWGWMI--VAGC---FVVTVCTRAVTRCISIFFVEFQMHFAKDYSGTAWIHSLVDCTTMLCA 83

  Fly    99 IVNGAMFRRFTFRQVALTGTSLAFLGVFLSAFCTTFWQYIICLSAIFGIGLGLAMAATSLAVNTY 163
            .:...:..:.:.|...:.|..||.:|:.||:|.|:.......|..:.|:|..|........|..|
Zfish    84 PLGSLIGNQLSCRIAVILGGFLASVGLVLSSFATSLEYLYATLGLLTGLGFALCYTPAIAMVGIY 148

  Fly   164 FKLKRRRATGFSWTITGLGPIFFPQVSTVLLGYYGAQGTILIYAGIAMNAILCALTLQPVLWHVK 228
            |..::..|.|.:.:.:|:|......|..:|:.:|..:|.:||..|..:|..:|...|:|::  :|
Zfish   149 FCERKALAYGIAMSGSGIGTFILAPVVQLLIEHYSWRGALLILGGFVLNLCVCGALLRPII--LK 211

  Fly   229 KPEK---PVHNTIEGIAETEKLQPELLEANGNLLSPSNDPWKDYECKYCQYQKRSKRGLFSSQYL 290
            :.|.   ||                                 |.||
Zfish   212 EEEACPLPV---------------------------------DSEC------------------- 224

  Fly   291 FNVDDPERPGYEITEPGTPMLARANDGWFGSKLSLTSESAGGARSRTRQALMRQVSSRSRENLDR 355
                     ||.:..|..
Zfish   225 ---------GYSVKPPTL----------------------------------------------- 233

  Fly   356 LEQNRHDQGPDTPSAAALYKPNYFNREREDLDRYASKTSVYSRPGQDELLRCTCAEDKALLQKTA 420
                   .|..|.|||:
Zfish   234 -------NGGPTRSAAS------------------------------------------------ 243

  Fly   421 ESLQVNLFNNSADNTEAEEEAKRRMTFFQKVSKFFDLDLLRDF-----TFVNLAVGMSIMMFGEM 480
                               :||:|.  ||.:.::..| |:.||     :|:.||.|.|      :
Zfish   244 -------------------DAKQRC--FQSMQEYHFL-LMPDFLVLAGSFLLLASGCS------L 280

  Fly   481 NFSVLTPFILNSFGYTDTQISLVMSLLACMDI--SVRF--LAPLALEKVKLDNRVLFAFGILC-- 539
            .|..|.|:.|: .|......:.:||:|..:||  ::.|  |.         |.|.|..:..:|
Zfish   281 PFVYLVPYALD-VGVGHQHAAFLMSILGVIDIVGNITFGWLT---------DRRCLKKYRNICYM 335

  Fly   540 IAVGR-----VVVAFTDSYEIMIGVFLLIGFGKAFRTIFSPLIIPSYVPLNRLPAASGLQLIFNT 599
            .|||.     :.:....::..::...:|.|:.........|::....|....|.:|.|:....:.
Zfish   336 FAVGMEGLCCLFIPLLRTFVWLVPFSVLYGYFDGAYVALIPVVTSDVVGRQYLSSALGVVYFLHA 400

  Fly   600 IFSFAMGPILGILTEAYG-YAATIHTINALTLLALLLWLAESVVR 643
            :......||.|.|.:..| |.||........:.:.||..:.:::|
Zfish   401 VPYLVSPPIGGWLVDTTGTYTATFFLSGFALISSSLLLFSVAIIR 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
out	NP_001285435.1	MFS	45..>225	CDD:119392	44/184 (24%)
		MFS	<464..621	CDD:119392	37/168 (22%)
		MFS_1	468..>621	CDD:284993	36/164 (22%)
slc16a12b	NP_001139286.1	MFS	33..430	CDD:119392	106/602 (18%)
		MFS_1	37..407	CDD:284993	96/572 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578817
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.850