Protein Alignment out and slc16a12

DIOPT Version :9

• Sequence 1: NP_001285435.1
• Gene: out / 32926
• FlyBaseID: FBgn0259834
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_989310.1
• Gene: slc16a12 / 394932
• XenbaseID: XB-GENE-1012784
• Length: 473
• Species: Xenopus tropicalis
• Alignment Length: 649
• Identity: 112/649 - (17%)
• Similarity: 206/649 - (31%)
• Gaps: 239/649 - (36%)

  Fly    39 PDGGWGWVVCLAAGLNNFFL---FPALQQYGLIYRVRMQS-LGFDAKQTTTIVNVVMAISSLVGI 99
            |||||||::.:..    ||:   ..|:.:...|:.|..|| ...|..:|..|.::|...:.|...
 Frog    13 PDGGWGWMIVIGC----FFVTVCTRAVTRCISIFFVEFQSYFAQDYARTAWIHSIVDCSTMLCAP 73

  Fly   100 VNGAMFRRFTFRQVALTGTSLAFLGVFLSAFCTTFWQYIICLSAIFGIGLGLAMAATSLAVNTYF 164
            :...:...|:.:...:.|..||..|:.||:|.|:.....:.|..:.|:|..|..:.....|..||
 Frog    74 IGSYVSNHFSCQVGIILGGVLASTGLVLSSFATSLEYLYLTLGVLTGLGFALCYSPAIAMVGKYF 138

  Fly   165 KLKRRRATGFSWTITGLGPIFFPQVSTVLLGYYGAQGTILIYAGIAMNAILCALTLQPV------ 223
            :.::..|.|.:.:.:|:|......|..:|:..:..:|.:||..|...|..:|...::|:
 Frog   139 EKRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVSNLCVCGALMRPITLKEDS 203

  Fly   224 LWHVKKPEKPVHNTIEGIAETEKLQPELLEANGNLLSPSNDPWKDYECKYCQYQKRSKRGLFSSQ 288
            |.:..|.|:         .|.|..|...|:::.:.|           |:.|.:::
 Frog   204 LHYPLKQEQ---------MENEPTQSGRLDSSCSPL-----------CQDCSHKR---------- 238

  Fly   289 YLFNVDDPERPGYEITEPGTPMLARANDGWFGSKLSLTSESAGGARSRTRQALMRQVSSRSRENL 353
                                                                             
 Frog   239 ----------------------------------------------------------------- 238

  Fly   354 DRLEQNRHDQGPDTPSAAALYKPNYFNREREDLDRYASKTSVYSRPGQDELLRCTCAEDKALLQK 418
                                                              |..||
 Frog   239 --------------------------------------------------LCYCT---------- 243

  Fly   419 TAESLQVNLFNNSADNTEAEEEAKRRMTFFQKVSKFFDLDLLRDFTFVNLAVGMSIMMFGEMNFS 483
                                   |:..:|..| .||..|.:    :|:.||.|.|      ..|.
 Frog   244 -----------------------KKEYSFLLK-PKFMVLAV----SFLFLAYGCS------PPFV 274

  Fly   484 VLTPFILNSFGYTDTQISLVMSLLACMDI----------SVRFLAP----LALEKVKLDNRVLFA 534
            .|.|:.|| .|.::.:.:.:||:|..:||          ..|||..    ..|..|.||
 Frog   275 YLVPYALN-VGVSNQEAAFLMSILGIIDIVGNITFGWVTDTRFLKKHRYCCYLIAVGLD------ 332

  Fly   535 FGILCIAVGRVVVAFTDSYEIMIGVFLLIGFGKAFRTIFSPLIIPSYVPLNRLPAASGLQLIFNT 599
             |:.|:     .:.....:::::...::.|:.........|::....|..:.|.:|.|:....:.
 Frog   333 -GLCCL-----FLPILTRFQLLVPFSVMFGYFDGAYVALIPVVTGDVVGTSSLSSALGVVFFLHA 391

  Fly   600 IFSFAMGPILGILTEAYGYAATIHTINALTLL--ALLLWLAESVVRRI------LGIPSKGLGQ 655
            :......||.|.|.:..|.......::..:::  |:||.||: ::.||      :.:|:..:.|
 Frog   392 VPYLVSPPIAGWLVDTTGDYTAAFLLSGFSMIFCAVLLALAK-IINRIKKRPKAVAVPTSDIKQ 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
out	NP_001285435.1	MFS	45..>225	CDD:119392	42/189 (22%)
		MFS	<464..621	CDD:119392	36/170 (21%)
		MFS_1	468..>621	CDD:284993	35/166 (21%)
slc16a12	NP_989310.1	2A0111	12..444	CDD:331689	110/637 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.020