DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment out and CG13907

DIOPT Version :9

Sequence 1:	NP_001285435.1	Gene:	out / 32926	FlyBaseID:	FBgn0259834	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	NP_001286894.1	Gene:	CG13907 / 38104	FlyBaseID:	FBgn0035173	Length:	816	Species:	Drosophila melanogaster

Alignment Length:	742	Identity:	143/742 - (19%)
Similarity:	268/742 - (36%)	Gaps:	170/742 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 TKPKKPKRRDKSD--------------LGPDFVAPDGGWGWVVCLAAGLNNFFLFPALQQYGLIY 69
            |..:.|:..|..|              |.|   .||||:|||:|.|:.:.|..:......:| |:
  Fly    41 TAEQSPEDEDNQDNDEDDDDEESVYGELPP---PPDGGYGWVICFASFMCNMIVDGIAYTFG-IF 101

  Fly    70 RVRMQSLGFDAKQTTTIV-NVVMAISSLVGIVNGAMFRRFTFRQVALTGTSLAFLGVFLSAFCTT 133
            .....:...:.|.|...| :::..:....|.:..|:..::..|.|.:.|:.:|.:...||.|.|.
  Fly   102 LEEFVAYFHEGKGTVAWVGSLLSGVYLSAGPIVSALANKYGCRAVCIAGSIIACIAFVLSTFSTN 166

  Fly   134 FWQYIICLSAIFGIGLGLAMAATSLAVNTYFKLKRRRATGFSWTITGLGPIFFPQVSTVLLGYYG 198
            ....:.....:.|.|.|:......:||..||:.||..|||.:...:|.|...|..::|.||..||
  Fly   167 VSMLMATYGFMGGFGFGMIYLPAVVAVGYYFETKRSLATGIAVCGSGFGTFAFAPLATYLLEEYG 231

  Fly   199 AQGTILIYAGIAMNAILCALTLQPVLWHVKKPEKPV---------------------------HN 236
            .:..:||:||:.:|..:....::|:.:..||.:||:                           ..
  Fly   232 WKNALLIFAGLILNCAIFGAMMRPLTYPKKKKQKPLMQRMYEEKQLQLERGSFAGSHFMVQLPDG 296

  Fly   237 TIE-----------GIAETEKLQ-----------------PELLEA--------NGNLLSPSND- 264
            |||           |:..:..|:                 |.:.|:        ||....|:.|
  Fly   297 TIERKLKMPLNADPGVHSSLNLELLAQQAGGGGLHPVSTLPTITESKVVDVHRQNGAQSPPNGDS 361

  Fly   265 ----------------PWKDYECKYCQYQKRSKRGLFSSQYLFNVDDPERPGYEITEPGTPMLAR 313
                            |.::.|.:...|..:......:||..|...|.:......:.|.
  Fly   362 NGQLSARSAAGAVGRRPHRNSESENSPYHSQDAMTRNASQPAFLAGDHQSLPKNGSVPA------ 420

  Fly   314 ANDGWFGSKLSLTSESAGGARSRTRQALMRQVSSRSRENLD----------RLEQNRHDQGPDTP 368
                 |.:::..||      .|...|..:..:.:.||.:|:          :|..::...|..|.
  Fly   421 -----FNTRVRKTS------ASERFQPSLAAIRATSRGDLEAGAGGDFASSKLSLSQRQGGSQTG 474

  Fly   369 SAAALYKPNYFNREREDLDRYASKTSVYSRPGQDELLRCTCAEDKALLQKTAESLQVNLFNNSAD 433
            |:..:.:|    ..|:|:....|.|::.....|..|  .........|.|..:|:|      |..
  Fly   475 SSGRMVRP----MSRKDIFYSGSVTNLPQYQSQKSL--ANYRNSVLSLTKYEKSMQ------SVA 527

  Fly   434 NTEAEEEAKRRMTFF-------------QKVSKFFDLDLLRDFTFVNLAVGMSIMMFGEMNFSVL 485
            ..:...||::....:             ..|:...|:.||:|..|  :.:|:| .:||.....|.
  Fly   528 KLDPLAEAEKHREEYDLCPCLGIPDSVKSVVNTMLDVSLLKDPVF--MLIGVS-NIFGMAGLYVP 589

  Fly   486 TPFILNSFGYTD---TQISLVMSLLACMDISVRFLAPLALEKVKLDNRVLFAFGILCIAVGRVVV 547
            ..:::::....|   ...::::|::...:...|.......:..::::.:|   ...|:.|..:.|
  Fly   590 FVYLVDAAKEHDIPKNDAAMLLSIIGITNTVGRVFCGWVADLPQVNSLLL---NNCCLLVSTIAV 651

  Fly   548 AFTD---SYEIMIGVFLLIGFGKAFRTIFSPLIIPSYVPLNRLPAASGLQLIFNTIFSFAMGPIL 609
            ..|.   ||...|.:.:..|...:.....:.:|:...:.|::|..|.||.::|....:....|:.
  Fly   652 TLTPLCYSYAAYITMSIFFGLAISGYISLTSIILVDLLGLDKLTNAFGLLILFRGFAALIGTPLA 716

  Fly   610 GI---LTEAYG----YAATIHTINALT 629
            |.   :|..|.    .|..:..|:.:|
  Fly   717 GAIYDMTHTYDLPFYMAGALFGISTIT 743

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
out	NP_001285435.1	MFS	45..>225	CDD:119392	46/180 (26%)
		MFS	<464..621	CDD:119392	30/169 (18%)
		MFS_1	468..>621	CDD:284993	29/165 (18%)
CG13907	NP_001286894.1	MFS	78..>258	CDD:119392	46/180 (26%)
CG13907	NP_001286894.1	MFS	<570..748	CDD:119392	32/180 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446232
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
	6	5.850