DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment out and slc16a3b

DIOPT Version :9

Sequence 1:	NP_001285435.1	Gene:	out / 32926	FlyBaseID:	FBgn0259834	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	NP_997873.1	Gene:	slc16a3b / 327276	ZFINID:	ZDB-GENE-030131-5487	Length:	508	Species:	Danio rerio

Alignment Length:	226	Identity:	61/226 - (26%)
Similarity:	102/226 - (45%)	Gaps:	8/226 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 DKSDLGPDFVAPDGGWGWVVCLAAGLNNFFLFPALQQYGLIYRVRMQSLGFDAKQTTTIVNVVMA 92
            |..|.|  ..||||||||.|.....:...|.:...:...:.::..::..|.....|..|.::::|
Zfish     7 DTGDSG--VKAPDGGWGWAVLFGCFIITGFSYAFPKAVSVFFKELIREFGVGYSDTAWISSILLA 69

  Fly    93 ISSLVGIVNGAMFRRFTFRQVALTGTSLAFLGVFLSAFCTTFWQYIICLSAIFGIGLGLAMAATS 157
            :....|.:...:..||..|.|.:.|...|.||:.|::|.|......:|...|.|:||.|....:.
Zfish    70 MLYGTGPLCSILVNRFGCRPVMMVGGLFASLGMVLASFATNIIHIYLCTGVITGLGLALNFQPSL 134

  Fly   158 LAVNTYFKLKRRRATGFSWTITGLGPIFFPQVSTVLLGYYGAQGTILIYAGIAMNAILCALTLQP 222
            :.:|.||..||..|.|.:...:.:.......:..||...||.:|..||..|:.:|...|...::|
Zfish   135 IMLNRYFSEKRPLANGLAAAGSPVALCCLSPLGQVLQYKYGWRGGFLILGGLLLNCCACGALMRP 199

  Fly   223 VLWHVKKPEKPVHNTIEGIAETEKLQPELLE 253
            :|    .|:|.  :.:|...:..|.:|:||:
Zfish   200 LL----APKKT--SEVEEKPKETKPKPKLLD 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
out	NP_001285435.1	MFS	45..>225	CDD:119392	43/179 (24%)
		MFS	<464..621	CDD:119392
		MFS_1	468..>621	CDD:284993
slc16a3b	NP_997873.1	MFS	22..410	CDD:119392	51/209 (24%)
slc16a3b	NP_997873.1	MFS_1	25..376	CDD:284993	49/206 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578826
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.940