Protein Alignment out and Slc16a6

DIOPT Version :10

• Sequence 1: NP_573378.1
• Gene: out / 32926
• FlyBaseID: FBgn0259834
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_001402062.1
• Gene: Slc16a6 / 303772
• RGDID: 735117
• Length: 538
• Species: Rattus norvegicus
• Alignment Length: 679
• Identity: 120/679 - (17%)
• Similarity: 228/679 - (33%)
• Gaps: 213/679 - (31%)

  Fly     2 EKSSLTEKN---------HTQVYNDTTKPKKPKRRDKSDLGPDFVAPDGGWGWVVCLAAGLNNFF 57
            |:|.:|:||         :|||                        |||||||||..:......|
  Rat    13 ERSRMTQKNSKLCSRANVYTQV------------------------PDGGWGWVVAASFFFIEVF 53

  Fly    58 LFPALQQYGLIYRVRMQSLGFDAKQTTTIVNVVMAISSLVGIVNGAMFRRFTFRQVALTGTSLAF 122
            .:..::.:|:.:...|.|......:.:.|:::.:.|.:....::..:..||..|.|.:.|..|..
  Rat    54 TYGVIKSFGVFFNDLMDSFDESNSKISWIISICVFIMTFTAPLSTILTNRFGHRLVVMGGGLLIS 118

  Fly   123 LGVFLSAFCTTFWQYIICLSAIFGIGLGLAMAATSLAVNTYFKLKRRRATGFSWTITGLGPIFFP 187
            :|:..::|....:|..|.:..:.|:|...:...|...::.||..:|...|..:.|........|.
  Rat   119 VGMIAASFSQRVYQMYISIGIVSGLGYCFSFLPTVTILSQYFDKRRSMVTAVASTGECFAMFAFA 183

  Fly   188 QVSTVLLGYYGAQGTILIYAGIAMNAILCALTLQPVLWHVKKPEKPVHNTIEGIAETEKLQPELL 252
            ...|.|..:.|.:.::|....:.:|.::|...|:|::  :|.|..|            |..|
  Rat   184 PAITALKEHIGWRYSLLFVGLLQLNVMVCGALLRPII--IKGPGSP------------KAIP--- 231

  Fly   253 EANGNLLSPSNDPWKDYECKYCQYQKRSKRGLFSSQYLFNVDDPERPGYEITEPGTPMLARANDG 317
                  |.|..      |.:|....::::..:.|      :|.    |.|:|.
  Rat   232 ------LEPRR------EVQYMLENEKTRTSIDS------IDS----GVELTT------------ 262

  Fly   318 WFGSKLSLTSESAGGARSRTRQALMRQVSSRSRENLDRLEQNRHDQGPDTPSAAALYKPNYFNRE 382
               |..::.||:                   .||...|:||.:          ..:..|.:
  Rat   263 ---SPKNVPSEA-------------------KREQEVRVEQQQ----------TLVVGPKH---- 291

  Fly   383 REDLDRYASKTSVYSRPGQDELLRCTCAEDKALLQKTAESLQVNLFNNSADNTEAEEEAKRRMTF 447
                                                                             
  Rat   292 ----------------------------------------------------------------- 291

  Fly   448 FQKVSKFFDLDLLRDFTFVNLAVGMSIMMFGEMNFSVLTPFILN---SFGYTDTQISLVMSLLAC 509
            .||.:...|..:|:|.:|:...:   ..:|..:.|...:.:|:.   |.|....:.:.::|.:|.
  Rat   292 SQKRAPLLDFSILKDRSFICYTL---FGLFATLGFFAPSLYIIPLGISLGIHPDRAAFLLSTMAI 353

  Fly   510 MDISVRFLAPLALEKVKLDNRVLFAFGILCIAVGRV-VVAFTDSYEIMIGVFLLIGFGKAFRTI- 572
            .::..|....|.|.:..:  |.:: ..::|:.:..| :.|||.:.|....:...:.||....||
  Rat   354 AEVFGRIGMGLVLNREPI--RKIY-IELICVILLTVSLFAFTFATEFWGLMLCSVFFGSMVGTIG 415

  Fly   573 --FSPLII-PSYVPLNRLPAASGLQLIFNTIFSFAMGPILGILTEA--------YGYAATIHTIN 626
              ..||:. ...|.:.::.:|:|:.:...:|...|..|:.|:|.:.        |..||
  Rat   416 GTHIPLLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAA------ 474

  Fly   627 ALTLLALLLWLAESVVRRILGIPSKGLGQ 655
            .:.|.|:.|.|.....:.:...|..|..|
  Rat   475 GMALAAVCLALVRPCKKGLCQNPHSGENQ 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
out	NP_573378.1	MFS	44..>221	CDD:475125	35/176 (20%)
		MFS	<459..626	CDD:475125	37/182 (20%)
Slc16a6	NP_001402062.1	MFS_MCT7	40..487	CDD:340980	104/610 (17%)