Protein Alignment out and Slc16a4

DIOPT Version :10

• Sequence 1: NP_573378.1
• Gene: out / 32926
• FlyBaseID: FBgn0259834
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_001013935.1
• Gene: Slc16a4 / 295356
• RGDID: 1359655
• Length: 500
• Species: Rattus norvegicus
• Alignment Length: 644
• Identity: 119/644 - (18%)
• Similarity: 216/644 - (33%)
• Gaps: 206/644 - (31%)

  Fly    25 KRRDKSDLGPDFVAP-DGGWGWVVCLAAGLNNFFLFPALQQYGLIYRVRMQSLGFDAKQTTTIVN 88
            ||.:|..   .:..| ||||||:|.|...|.|.|:....:.:.:.:.|..:.....::|...|.:
  Rat     3 KREEKPS---PYTKPLDGGWGWMVVLHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGS 64

  Fly    89 VVMAISSLVGIVNGAMFRRFTFRQVALTGTSLAFLGVFLSAFCTTFWQYIICLSAIFGIGLGLAM 153
            ::.::....|.:...:...|..:..::.||.|...|..:|::.|......:.:..:.|:|.....
  Rat    65 IMSSLRFSAGPLAAIICDIFGEKTTSILGTFLVSGGYLISSWATGIPFLCVTMGLLPGLGSAFLY 129

  Fly   154 AATSLAVNTYFKLKRRRATGFSWTI--TGLGPIF-FPQVSTVLLGYYGAQGTILIYAGIAMNAIL 215
            ...::.:..|||    :..|.|..|  :|:|..| ....:.:|:..|...|.::::..||:|.:.
  Rat   130 QVAAVVITKYFK----KRLGLSTAIARSGMGLTFLLAPFTKLLIDLYDWTGALILFGAIALNLVP 190

  Fly   216 CALTLQPVLWHVKKPEKPVHNTIEGIAETEKLQPELLEANGNLLSPSNDPWKDYECKYCQYQKRS 280
            .::.|:||  |::....          ...|.:..:|.|.|..||...:
  Rat   191 SSMLLRPV--HIQSDSN----------SDIKNKGSILSATGPELSHKTE---------------- 227

  Fly   281 KRGLFSSQYLFNVDDPERPGYEITEPGTPMLARANDGWFGSKLSLTSESA---GGARSRTRQALM 342
                                       ||...:|.:       ||..:||   .|..:.|...|.
  Rat   228 ---------------------------TPNRNKAQE-------SLIKDSAVKKSGQPTTTLTVLE 258

  Fly   343 RQVSSRSRENLDRLEQNRHDQGPDTPSAAALYKPNYFNREREDLDRYASKTSVYSRPGQDELLRC 407
            .|:        :.:....|...|...|....||..:                          :..
  Rat   259 NQI--------EEISTRPHRNRPLLMSNDKTYKKKF--------------------------VSW 289

  Fly   408 TCAEDKALLQKTAESLQVNLFNNSADNTEAEEEAKRRMTFFQKVSKFFDLDLLRDF--TFVNLA- 469
            .|.|         :.|.::||.|               .||...:..|.|..|..|  ||..:|
  Rat   290 NCKE---------KLLDISLFRN---------------PFFYIFTWSFLLSQLAYFIPTFHLVAR 330

  Fly   470 ---VGMSIMMFGEMNFSVLTPFILNSFGYTDTQISLVMSLLACMDISVRF--------------- 516
               :|:.||.         ..::::..|.|:|...|:...:|..:...::
  Rat   331 AKTLGIDIMD---------ASYLVSVAGITETVSQLISGWIADQNWIKKYQYHKAYLILCGVTNL 386

  Fly   517 LAPLALEKVKLDNRVLFAFGILCIAVGRVVVAFTDSYEIMIGVFLLIGFGKAFRTIFSPLIIPSY 581
            |||||.           .|.:|        :|:|..:.|..|.:|             .||:|..
  Rat   387 LAPLAT-----------TFPLL--------MAYTIFFAIFAGGYL-------------ALILPVL 419

  Fly   582 VPL---NRLPAASGLQLIFNTIFSFAMGPILGIL---TEAY----GYAATIHTINALTL 630
            |.|   :|:....|....|..:...:..||.|.:   |:.|    .::.|.:.:::::|
  Rat   420 VDLSKNSRVHRFLGYASFFAGMAVLSGPPIAGWIYDYTQTYVGSFYFSGTCYILSSVSL 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
out	NP_573378.1	MFS	44..>221	CDD:475125	35/179 (20%)
		MFS	<459..626	CDD:475125	39/197 (20%)
Slc16a4	NP_001013935.1	MFS_MCT5	20..486	CDD:340979	111/624 (18%)