DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment out and Slc16a11

DIOPT Version :9

Sequence 1:	NP_001285435.1	Gene:	out / 32926	FlyBaseID:	FBgn0259834	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	NP_694721.2	Gene:	Slc16a11 / 216867	MGIID:	2663709	Length:	447	Species:	Mus musculus

Alignment Length:	334	Identity:	73/334 - (21%)
Similarity:	114/334 - (34%)	Gaps:	80/334 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 TTKPKKPKRRDKSDLGPDFVAPDGGWGWVVCLAAGLNNFFLFPALQQYGLIYRVRMQSLGFDAKQ 82
            |.||..|              |||||||||..||...|...:..|:..||......:.....|:.
Mouse     2 TPKPAGP--------------PDGGWGWVVAAAAFAVNGLSYGLLRSLGLALPDLAEHFERSAQD 52

  Fly    83 TTTIVNVVMAISSLVGIVNGAMFRRFTFRQVALTGTSLAFLGVFLSAFCTTFWQYIICLSAIFGI 147
            |..:..:.:|:......|..|:..|:..|.|.:.|..|..||:..|||..:.....:.|..:.|.
Mouse    53 TAWVSALALAVQQAASPVGSALSTRWGARPVVMVGGVLTSLGLVFSAFARSLLHLYLGLGLLAGS 117

  Fly   148 GLGLAMAATSLAVNTYFKLKRRRATGFSWTITGLGPIFFPQVSTVLLGYYGAQGTILIYAGIAMN 212
            |..|..|.....::.||..:|..|.|.:.|..|...:........||..:|.:|.:|:...:.::
Mouse   118 GWALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQFLLDTFGWRGALLLLGAVTLH 182

  Fly   213 AILCALTLQPVLWHVKKPEKPVHNTIEGIAETEKLQPELLEANGNLLSPSNDPWKDYECKYCQYQ 277
            ...|...|:|                             |..:|:.|:|...|......
Mouse   183 LTPCGALLRP-----------------------------LALSGDPLAPPRTPLAALGL------ 212

  Fly   278 KRSKRGLFSSQYLFNVDDPERPGYEITEPGTPMLA------------RAND---GWFGSKLSLTS 327
                 |||           :|..:.:...||.::.            .|.|   |.:|:.|.:..
Mouse   213 -----GLF-----------KRRAFSVFALGTALIGGGYFVPYVHLGPHALDQGMGGYGAALVVAV 261

  Fly   328 ESAGGARSR 336
            .:.|.|.:|
Mouse   262 AAVGDACAR 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
out	NP_001285435.1	MFS	45..>225	CDD:119392	44/179 (25%)
		MFS	<464..621	CDD:119392
		MFS_1	468..>621	CDD:284993
Slc16a11	NP_694721.2	MFS	14..403	CDD:391944	64/308 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835569
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.891027	Normalized mean entropy	S3509
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.890