Protein Alignment out and mct-2

DIOPT Version :9

• Sequence 1: NP_001285435.1
• Gene: out / 32926
• FlyBaseID: FBgn0259834
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_503681.2
• Gene: mct-2 / 182056
• WormBaseID: WBGene00015273
• Length: 544
• Species: Caenorhabditis elegans
• Alignment Length: 598
• Identity: 127/598 - (21%)
• Similarity: 214/598 - (35%)
• Gaps: 161/598 - (26%)

  Fly    39 PDGGWGWVVCLAAGLNNFFLFPALQQYGLIYRVRMQSLGFDAKQTTTIVNVVMAISS----LVGI 99
            ||||:||||..|:.|.|..:...:...|.|    :..:..|...:|::...|::|.:    |.|.
 Worm    40 PDGGYGWVVVAASFLVNMAVDGVIYTCGKI----LVPIWADQFGSTSVAGAVISILTGCYYLAGP 100

  Fly   100 VNGAMFRRFTFRQVALTGTSLAFLGVFLSAFCTTFWQYIICLSAIFGIGLGLAMAATSLAVNTYF 164
            :..:....|..|.||:.|:.||.....||.|.:|.|:..:....:.|||.|.....:.:.::|||
 Worm   101 LASSFVNVFGIRSVAIAGSILATTAFLLSRFASTIWELYLLFGVLGGIGFGCMYLPSIVILSTYF 165

  Fly   165 KLKRRRATGFSWTITGLGPIFFPQVSTVLLGYYGAQ-GTILIY-AGIAMNAILCALTLQPVL--- 224
            ..||..|||.:...:|:|.:.|..::..:..|:|.. |:.::| |.||::..|.:|...|:.
 Worm   166 AKKRSVATGIAVCGSGIGTMVFSTINGPVFDYFGKDVGSFMVYLAAIAISGSLFSLLFAPLKATE 230

  Fly   225 WHVKKPEKPVHNTIEGIAETEKLQPELLEANGNLLSPSNDPWKDYECKYCQYQKRSKRGLFSSQY 289
            ..|||..|.|.|                                ||.|
 Worm   231 HQVKKVAKMVRN--------------------------------YEGK----------------- 246

  Fly   290 LFNVDDPERPGYEITEPGTPMLARANDGWFGSKLSLTSESAGGARSRTRQALMRQVSSRSRENLD 354
                  ||.|                                      .|.|:..|    |.:|:
 Worm   247 ------PEEP--------------------------------------TQRLLEDV----RNDLE 263

  Fly   355 RLEQNRHDQGPDTPSAAALYKPNYFNREREDLDRYASKTSVYSRPGQDELLRCTCAEDKALLQKT 419
            .|                       ||...:.|.:.:..:..||           :....|.:|.
 Worm   264 EL-----------------------NRPGHNADTFYAGNAPVSR-----------SRSNTLDRKA 294

  Fly   420 AESLQVNLFNNSADNTEAEEEAKRRMT-FFQKVSKFFDLDLLRDFTFVNLAVGMSIMMFGEMNFS 483
            |||.:.::.:.:..:|......|.:.| |.:.:....|.|||...:|:.|||..:..:     .|
 Worm   295 AESAEAHVVHATEHHTVHHVVKKSKFTKFKESLCSVLDKDLLFSPSFMTLAVSGTFTV-----LS 354

  Fly   484 VLTPFILNSFG-------YTDTQISLVMSLLACMDISVRFLAPLALEKVKLDNRVLFAFGILCIA 541
            .|.||:..:..       :||.::||.::|:...:|..|....:..:..|:.  .|....:..|.
 Worm   355 FLVPFVYLALAMKQKNPDFTDAELSLPVTLIGAFNIMFRIGCGMVADHPKMS--ALQVSNVATII 417

  Fly   542 VGRVVVAFTDSYEIMIGVFLLIGF--GKAFRTIFSPLIIPSYVPLNRLPAASGLQLIFNTIFSFA 604
            .|..::......|:...|...|.|  |.|.......:|....:.:.:|..|.|:.::|..|.:..
 Worm   418 AGTSMLFVPFCTELWHYVVFCIPFSAGVACFAALRSVICVELIGVEKLSNAFGILMVFMGIGAVV 482

  Fly   605 MGPILGILTEAYG 617
            .|||...:.:..|
 Worm   483 GGPIAAQIKDITG 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
out	NP_001285435.1	MFS	45..>225	CDD:119392	51/188 (27%)
		MFS	<464..621	CDD:119392	35/163 (21%)
		MFS_1	468..>621	CDD:284993	34/159 (21%)
mct-2	NP_503681.2	MFS_MCT_SLC16	45..519	CDD:340910	123/593 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158597
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.891027	Normalized mean entropy	S3509
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.700