Protein Alignment out and mct-4

DIOPT Version :10

• Sequence 1: NP_573378.1
• Gene: out / 32926
• FlyBaseID: FBgn0259834
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_001041267.1
• Gene: mct-4 / 180766
• WormBaseID: WBGene00003986
• Length: 777
• Species: Caenorhabditis elegans
• Alignment Length: 696
• Identity: 135/696 - (19%)
• Similarity: 245/696 - (35%)
• Gaps: 187/696 - (26%)

  Fly    38 APDGGWGWVVCLAAGLNNFF---LFPALQQYGLIYRVRMQ-SLGFDAKQTTTIVNVVMAISSLVG 98
            |||||:|||:..||.::|..   :..|..::...|:.|.| |.|.    |..|.::::....|||
 Worm    69 APDGGYGWVIVFAAFMSNLVVDGISTAFSEFKQSYKERYQESDGL----TVFIGSLIIGTYLLVG 129

  Fly    99 IVNGAMFRRFTFRQVALTGTSLAFLGVFLSAFCTTFWQYIICLSAIFGIGLGLAMAATSLAVNTY 163
            .:..|:..::..|.|.:.|..::.:...::......:.:::....:.|:|.|:......:.|..|
 Worm   130 PLVSALCNKYEQRYVVMAGGLISGIAFMIAPASPNIYVFMLIYGVMGGLGFGMIYLPAIVVVGFY 194

  Fly   164 FKLKRRRATGFSWTITGLGPIFFPQVSTVLLGYYGAQGTILIYAGIAMNAILCALTLQPVLWHVK 228
            |..||..|||.|...:|:|....|.:..|.:...|.|.||.:.|.:..:.:......:|:
 Worm   195 FDSKRAMATGISVAGSGVGTFLVPLICQVCIANLGWQKTIWVLAVMIFSCVFYGYLYRPL----- 254

  Fly   229 KPEKPVHNTIEGIAETEKLQPELLEANGNLLSPSNDPWKDYECKYCQYQKRSKRGLFSSQYLFNV 293
                |:.:..|  ...::::|                                    ..|.|..|
 Worm   255 ----PMVDLNE--IRDQEMEP------------------------------------LRQALSKV 277

  Fly   294 DDPERPGYEITEPGTPMLARANDGWFGSKLSLTSESAGGARSRTRQALMRQVSSRSRENLDRLEQ 358
            :|.|....|...|...                ||.::|        |:..:..|::.| :.||..
 Worm   278 EDDEDEAVESPHPNRS----------------TSAASG--------AIEDEAVSQNPE-VQRLRS 317

  Fly   359 --NRHDQGPDTPSAAALYKPNYFNREREDLDRYASKTSVYSRPGQD---ELLRCTCAEDKAL--- 415
              ...|:|.:||.:.|       ::.|......:.|.::.|..|..   :|.|...:.|..|
 Worm   318 ILTEGDEGSETPKSDA-------HKVRSHTATRSRKHTMTSNSGSQHDLKLSRGNLSSDNRLSRV 375

  Fly   416 -----------LQKTAESLQVNLFNNSADNTEAEEEAKRRMTFF----QKVSKFFDLDLLRDFTF 465
                       |.|:..:..:::..:..|..|.:....|:..|:    |.:.:|.:...:..:..
 Worm   376 SARDFNQSLSKLSKSGGASNLSIAMSGVDPKEFQRPMNRQDIFYGGSIQNLKEFKEEGTMAGYRA 440

  Fly   466 VNLAVGMSIM--MFGEMNFS-----------------VLTPFI---------------------L 490
            ..|::..|::  ...::|.|                 ::.||:                     |
 Worm   441 STLSIPRSVVGQAVSQLNLSRTGSRLGGPGIAEDEEEMIEPFVDDGCCKVLPLPMRNALSEMIDL 505

  Fly   491 NSFGYTDTQISLVMSLLACMD--ISVRFLAPLALEKVKLD-NRVLF---AFGILCIAVGRVVVAF 549
            |........|..:.:||..|.  |.:.||..|: |.:||| :..:|   .||:. ..:|||...:
 Worm   506 NLLKNKTMMILCISNLLGMMGFYIPIMFLKDLS-ESMKLDMSLAMFLVPIFGVF-NTIGRVFFGW 568

  Fly   550 TDSYEIMIGV------FLLIGF------------GKAFRTIFSPLIIPSYVPLNRLPAAS----- 591
            ....:|:..:      .::.|.            |:.|..|....||.:|:.|..:..|.
 Worm   569 LTDQKILSALTINNLSLIVSGLLTLACPLLTSIAGQYFYAIVFGFIISAYICLTSIVLADLMGLE 633

  Fly   592 ------GLQLIFNTIFSFAMGPILGILTEAYGYAATIHTINALTLL 631
                  ||.::...|.|....|..||:.:..|...|......|.||
 Worm   634 NLTNSFGLLVVARGIASLVGPPFAGIVYDITGSYDTAFYFGGLVLL 679

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
out	NP_573378.1	MFS	44..>221	CDD:475125	42/180 (23%)
		MFS	<459..626	CDD:475125	45/241 (19%)
mct-4	NP_001041267.1	MFS_MCT_SLC16	75..>252	CDD:340910	42/180 (23%)
		MFS	<507..689	CDD:475125	40/175 (23%)