Protein Alignment out and Mct1

DIOPT Version :10

• Sequence 1: NP_573378.1
• Gene: out / 32926
• FlyBaseID: FBgn0259834
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: XP_311120.3
• Gene: Mct1 / 1272237
• VectorBaseID: AGAMI1_011930
• Length: 606
• Species: Anopheles gambiae
• Alignment Length: 676
• Identity: 147/676 - (21%)
• Similarity: 249/676 - (36%)
• Gaps: 154/676 - (22%)

  Fly    18 TTKPKKPKRRDKSDLGPDF-------------VAPDGGWGWVVCLAAGLNNFFLFPALQQYGLIY 69
            |..|...::|.:..:..|.             ..|||||||:|.||:...:.........:|:.|
Mosquito     2 THGPPASRKRQQQQIDSDIEQSVTEVDPNGLPTPPDGGWGWMVVLASFSIHIITDGLTYSFGIFY 66

  Fly    70 RVRMQSLGFDAKQTTTIVNVVMAISSLVGIVNGAMFRRFTFRQVALTGTSLAFLGVFLSAFCTTF 134
            ...:.........|..|.::::.::...|.::.::..|:..|.|.:.|..||...:.:|.:.|:.
Mosquito    67 SEFLTYFNEGKGYTAWIASILVGVTLCSGPISSSLVNRYGCRAVTIAGALLASASLAVSMYATSV 131

  Fly   135 WQYIICLSAIFGIGLGLAMAATSLAVNTYFKLKRRRATGFSWTITGLGPIFFPQVSTVLLGYYGA 199
            :...|.:....|:||||......::|..||:..|..|||.:...:|||...|..::..|:..:..
Mosquito   132 FMLFITIGVGTGLGLGLIYLPAIVSVTMYFERLRSLATGIAVCGSGLGTSIFAPLTEALIKKFQW 196

  Fly   200 QGTILIYAGIAMNAILCALTLQPVLWHVKKP-----EKPVHNTIE---------GIAETEKLQ-- 248
            ||.:|..|||.:..:|..|..:|::.....|     |.|.|::.:         |.|....|:
Mosquito   197 QGALLAIAGIVLICVLFGLMFRPLVHEPASPGKELQELPQHSSADPSTTMKPTSGNANESNLKRS 261

  Fly   249 --------PEL-LEANGNLLSPSNDPWKDYECKYCQYQKRSKRGLFSSQYLFNVDDPERP-GYEI 303
                    |:: |.|||:..|..|   .|...:....:...:.||  ||.|....:..:| ..:.
Mosquito   262 NSHGHVDAPKIDLNANGHSASGHN---LDKHTRTTPGEDAKRLGL--SQPLLTAPESVQPVPLKR 321

  Fly   304 TEPGTPMLARANDGWFGSKLSLTSESAGGARSRTRQALMRQVSSRSRENLDRLEQNRHD--QG-- 364
            ||.||  :.|.:..:.||..::.|..|                  |:.||...|:..:.  ||
Mosquito   322 TESGT--MYRKDALYTGSVHNIASRHA------------------SQANLSIYEKGSYGSVQGNG 366

  Fly   365 -------PDTPSAAALYKPNYFNREREDLDRYASKTSVYSRPGQDELLRCTCAEDKALLQKTAES 422
                   ||.|.......|    ..||..|.:.            |::..:..:|...:..|..:
Mosquito   367 LHRPPAEPDAPERCLGCIP----CSRETCDTFR------------EMMNFSILKDPIFIIFTVSN 415

  Fly   423 LQVNL-FNNSADNTEAEEEAKRRMTFFQKVSKFFDLDLLRDFTFVNLAVGMSIMMFGEMNFSVLT 486
            ...:: ||                                 ..:|.||....::..|..:.|
Mosquito   416 FLTSVGFN---------------------------------VPYVYLAAQAQVLGIGSKDAS--- 444

  Fly   487 PFILNSFGYTDTQISLVMSLLACMDISVRFLAPLALEKVKLD-NRVLFAFGILCIAVGRVVVAFT 550
             ::|...|..:|...:|:..|:    ...::..||:....|. ..:..|..:||:
Mosquito   445 -YLLGIIGIANTVGRIVLGYLS----DKPWVNRLAVYNCSLAVCGIATALSVLCV---------- 494

  Fly   551 DSYEIMIGVFLLI-GFGKAFRTIFSPLIIPSYVPLNRLPAASGLQLIFNTIFSFAMGPILGIL-- 612
            |.|  .:||:..: ||........:.:|:...:.|.:|..|.||.|:|..|.||...||.|.|
Mosquito   495 DFY--WLGVYSAVYGFTIGAYVGLTSVILVDLLGLEKLTNAFGLLLLFQGIASFVGPPIAGWLYD 557

  Fly   613 -TEAYG----YAATIHTINALTLLAL 633
             |.:||    .|.|...|:...|.|:
Mosquito   558 YTLSYGPGFIMAGTTIAISGAMLFAI 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
out	NP_573378.1	MFS	44..>221	CDD:475125	44/176 (25%)
		MFS	<459..626	CDD:475125	42/175 (24%)
Mct1	XP_311120.3	MFS_MCT_SLC16	41..584	CDD:340910	138/637 (22%)