Protein Alignment out and Sln

DIOPT Version :10

• Sequence 1: NP_573378.1
• Gene: out / 32926
• FlyBaseID: FBgn0259834
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: XP_061512092.1
• Gene: Sln / 1271075
• VectorBaseID: AGAMI1_000201
• Length: 873
• Species: Anopheles gambiae
• Alignment Length: 718
• Identity: 159/718 - (22%)
• Similarity: 285/718 - (39%)
• Gaps: 146/718 - (20%)

  Fly     8 EKNHTQVYNDTTKPKKPKRRDKSDLGPDFVAPDGGWGWVVCLAAGLNNFFLFPALQQYGLIYRVR 72
            :|.|.|      |.:||...|.|: ..|...||||:||::...|....|::...::.||::|...
Mosquito   195 QKLHIQ------KQRKPVASDTSE-DDDDSPPDGGYGWIIVFGAFSVQFWVAGLVKSYGVLYVEI 252

  Fly    73 MQSLGFDAKQTTT--IVNVVMAISSLVGIVNGAMFRRFTFRQVALTGTSLAFLGVFLSAFCTTFW 135
            |::.. :|..||.  |..::.|:..::..::.|:.:||:.|.|.:.|.....||:.||.|.|:.:
Mosquito   253 MENFP-NASATTASWIPAILSALCLVLAPLSSALCQRFSCRIVVIIGGVFCGLGLTLSYFATSMY 316

  Fly   136 QYIICLSAIFGIGLGLAMAATSLAVNTYFKLKRRRATGFSWTITGLGPIFFPQVSTVLLGYYGAQ 200
            ..:.....:.|||.||:.....:.|:.||:..|..|.|.:.:.|..|...||.:...|:..:|..
Mosquito   317 HLLFTFGILTGIGGGLSTTPGIVIVSQYFEKHRALANGITISGTAAGSFVFPMLIERLIHLFGFH 381

  Fly   201 GTILIYAGIAMNAILCALTLQPVLWHVKK----PEKPVHNTIEGIAETEKLQPELLEANGNLLSP 261
            ||:||..|..::..:.....:||   .||    |.|      ||...:.:  .:..|..|: ||.
Mosquito   382 GTLLILGGCMLHVCVSGALYRPV---EKKQDLVPSK------EGTQFSSR--SDFRENLGH-LSS 434

  Fly   262 SNDPWKDYECKYCQYQKRSKRGLFSSQYLFNVDDPERPG-------YEITEPG------------ 307
            |.|          ...||....||       :||..|..       ..|||..
Mosquito   435 SED----------HLSKRCLEDLF-------LDDQNRNSLTIDSKFVNITEKTLQESEDELKDIL 482

  Fly   308 ------TPMLARANDGWFGSKLSLTSESAGGARSRTRQALMRQVSSRSRENLDRLEQNRHDQGP- 365
                  .|:.:..:.....|...|:::|....::|......::.|.|.::...:|.|.|..|.|
Mosquito   483 SSAIFLKPISSIRSCSILHSVEDLSTDSTCVYKNRASGYDSKRNSMRYKQQQQQLHQARPQQPPP 547

  Fly   366 ----DTPSAA--------------------ALYKPNYFNREREDLDRYASK-------------- 392
                |.|..:                    .|..||       :||:..||
Mosquito   548 PQATDQPVGSQTTLGMAEGGGGGEAPLLGPLLLAPN-------ELDKPVSKDVPTKTLAANAGPL 605

  Fly   393 TSVYSRPGQDELLRCTCAEDKALLQKTAESLQVNLF--NNSADNTEAEEE---AKRRMTFFQKVS 452
            .:|.|....     |.....|.|.|.....|..::.  ....|..|..:|   .....|..:|:|
Mosquito   606 PTVMSSNNM-----CAMVPTKGLAQNNNRGLSKSMIIPTPVCDLDEIFDEDPYTVYNATLLEKIS 665

  Fly   453 KFFDLDLLRDFTFVNLAVGMSIMMFGEMNFSVLTPFILNSFGYTDTQISLVMSLLACMD----IS 513
            ::.|:.||:|.||:.:.:.:::|..|........|..:.|.|||.::...::::.|.:|    ::
Mosquito   666 QYLDITLLQDITFILMCLSVALMSVGCPYMLYYLPAYVISAGYTKSEAGYLVAVSAALDLIGRLA 730

  Fly   514 VRFLAPLALEKVKLDNRVLFAFGILCI-AVGRVVVAFTDSYEIMIGVFLLIG-FGKAFRT--IFS 574
            :.:|:.|.|    .|.:..:   |:|| ..|..|:....|......:.:..| :|....:  :..
Mosquito   731 LGWLSDLDL----FDRKKAY---IVCILGAGTAVLTIPTSSNAWFVIVISAGCYGLCLGSWYLLV 788

  Fly   575 PLIIPSYVPLNRLPAASGLQLIFNTIFSFAMGPILGILTE-AYGYAATIH------TINALTLLA 632
            |:::.......|:.::.||..:|.:|.:.::.|:.|:|.: :.||....:      .:.::.|:|
Mosquito   789 PVLLADLFGTERISSSYGLVRMFQSIGAISVPPLAGLLRDLSGGYEICFYCMGVCMVMGSVPLVA 853

  Fly   633 LLL 635
            ::|
Mosquito   854 IIL 856

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
out	NP_573378.1	MFS	44..>221	CDD:475125	47/178 (26%)
		MFS	<459..626	CDD:475125	37/181 (20%)
Sln	XP_061512092.1	None