DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment out and SLC16A10

DIOPT Version :9

Sequence 1:	NP_001285435.1	Gene:	out / 32926	FlyBaseID:	FBgn0259834	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	NP_061063.2	Gene:	SLC16A10 / 117247	HGNCID:	17027	Length:	515	Species:	Homo sapiens

Alignment Length:	221	Identity:	50/221 - (22%)
Similarity:	90/221 - (40%)	Gaps:	20/221 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 TTKPKKPKRRDKSDLGPDFVAPDGGWGWVVCLAAGLNNFFLFPALQQYGLIYRVRMQSLGFDAKQ 82
            |.:|.:|         |:  .|:|||||:|.|||...|..:|......|:::...:::.|  :|.
Human    55 TAEPHEP---------PE--PPEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFG--SKD 106

  Fly    83 TTTIVNVVMAISSL-VGI------VNGAMFRRFTFRQVALTGTSLAFLGVFLSAFCTTFWQYIIC 140
            ...:|.....:.|| :|:      :.......|..|:.|:.|.::.|:|:..|:|.::.....:.
Human   107 DDKMVFKTAWVGSLSMGMIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLT 171

  Fly   141 LSAIFGIGLGLAMAATSLAVNTYFKLKRRRATGFSWTITGLGPIFFPQVSTVLLGYYGAQGTILI 205
            ...||..|...|...:.:.:..|||.:.....|.....:.:..|..|.:..||:...|...|:.:
Human   172 YGIIFACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFYTLRV 236

  Fly   206 YAGIAMNAILCALTLQPVLWHVKKPE 231
            .........|...|.:|:....|..|
Human   237 LCIFMFVLFLAGFTYRPLATSTKDKE 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
out	NP_001285435.1	MFS	45..>225	CDD:119392	39/186 (21%)
		MFS	<464..621	CDD:119392
		MFS_1	468..>621	CDD:284993
SLC16A10	NP_061063.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..48
		2A0113	67..487	CDD:273325	45/198 (23%)
		MFS	71..470	CDD:119392	41/194 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145497
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750