DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment out and slc16a2

DIOPT Version :9

Sequence 1:	NP_001285435.1	Gene:	out / 32926	FlyBaseID:	FBgn0259834	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	XP_031747020.1	Gene:	slc16a2 / 100494635	XenbaseID:	XB-GENE-980579	Length:	499	Species:	Xenopus tropicalis

Alignment Length:	235	Identity:	59/235 - (25%)
Similarity:	96/235 - (40%)	Gaps:	22/235 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 PKRRDKSDLGPDFVAPDGGWGWVVCLAAGLNNFFLFPALQQYGLIYRVRMQ-------SLGFDAK 81
            |.:|::...|.   .|:||:||||.|||...:..:|.....:|:|| |.:|       ..|.|.|
Frog    40 PGKREEDGRGR---VPEGGFGWVVVLAATWCSGSIFGIQNSFGIIY-VMLQGEMDGTEEQGMDFK 100

  Fly    82 QTTTIVNVVMAISSLVGIVNGAMFRRFTFRQVALTGTSLAFLGVFLSAFCTTFWQYIICLSAIFG 146
             |..:.::.|.:......|......|...|:.:..|.:|||:|:..|:|..:..........:||
Frog   101 -TAWVGSLAMGMIFFCSPVVSIFTDRLGCRKTSSGGAALAFIGLLSSSFTKSLGVRYFTYGILFG 164

  Fly   147 IGLGLAMAATSLAVNTYFKLKRRRATGFSWTITGLGPIF---FPQVSTVLLGYYGAQGTILIYAG 208
            .|...|...:.:.:..|||.:.....|.   :.|...:|   .|.:..::.|..|.|.|..:.:.
Frog   165 CGCSFAFQPSLVILGHYFKKRLGLVNGI---VAGGSCVFTMCLPFLLKMMGGAIGLQHTFQVLSV 226

  Fly   209 IAMNAILCALTLQPVLWHVKKPEKPVHNTIEGIAETEKLQ 248
            .....|..:||.:|:|    .|........|.:|...|.|
Frog   227 FMFIQIFLSLTFKPLL----PPPVDFSKEKEKVAGRSKAQ 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
out	NP_001285435.1	MFS	45..>225	CDD:119392	46/189 (24%)
		MFS	<464..621	CDD:119392
		MFS_1	468..>621	CDD:284993
slc16a2	XP_031747020.1	MFS_MCT8	57..459	CDD:341023	53/215 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920