Protein Alignment CG8051 and SLC16A7

DIOPT Version :9

• Sequence 1: NP_001285434.1
• Gene: CG8051 / 32925
• FlyBaseID: FBgn0031012
• Length: 616
• Species: Drosophila melanogaster
• Sequence 2: XP_011537291.1
• Gene: SLC16A7 / 9194
• HGNCID: 10928
• Length: 504
• Species: Homo sapiens
• Alignment Length: 621
• Identity: 121/621 - (19%)
• Similarity: 208/621 - (33%)
• Gaps: 203/621 - (32%)

  Fly    45 APPTHTHSIAAASVPQKVPAKKKRDKSDLGEDFVAPDGGWGWLVSVASGVNILVTFALAQQFGIL 109
            |||.|.                            .|||||||:|..|:.::|..::|..:...:.
Human     7 APPVHP----------------------------PPDGGWGWIVVGAAFISIGFSYAFPKAVTVF 43

  Fly   110 FRDRMAGLGISSSELTTIINTQIAV--------------------SAFT--GLLNGP----LFRR 148
            |::.......:.||:..|.:..:||                    .:||  |...||    |..:
Human    44 FKEIQQIFHTTYSEIAWISSIMLAVMYAGGRIFESFLIFTSLRIQCSFTQSGSCLGPVSSVLVNK 108

  Fly   149 YTYRVVALVGSVLTFLGLFWMVFADTFAVYIMSFSILYGFGRGLTVSASSLAVNTYFKVKRRTAT 213
            |..|.|.:.|.:|..||:....|:.:.....::...:.|.|....:..:...:..||..||..|.
Human   109 YGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALTIIGKYFYRKRPMAN 173

  Fly   214 AFQFGVAGLG-PI----VCPYFATYMLYEFGVQGTTLLFAGASLHTIACSLIYQPVKWHVVKRDR 273
                |:|..| |:    :.| |..|:...||.:|:.|:.....|:  ||
Human   174 ----GLAMAGSPVFLSSLAP-FNQYLFNTFGWKGSFLILGSLLLN--AC---------------- 215

  Fly   274 DAEALQQVQPLAEREDQDEDIIKNVVEPETPVLPRANDGWFGSRASLNSVGTRNRLNTWEKSDSN 338
                                :..:::.|..|                |...::::..|.:..|
Human   216 --------------------VAGSLMRPLGP----------------NQTTSKSKNKTGKTED-- 242

  Fly   339 GHVELKRLSSKDSNPGRQLRSISVSHSIKEEEATGYNSDHEVQHTELTEKEKQELEDEKERQRRK 403
                       ||:|.:          ||.:::|
Human   243 -----------DSSPKK----------IKTKKST------------------------------- 255

  Fly   404 KLPFYMKVVIFFDMDLLRD---ITYVNLAVGITLINFVEINFAILTPFILSDLGFNKDQIALAMS 465
                :.||..:.|..|.:.   :.|::..|.:.|..|..|.|  |.|: ..|.|.::...|..:|
Human   256 ----WEKVNKYLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIF--LAPY-AKDQGIDEYSAAFLLS 313

  Fly   466 TLGFFDLVVRFLIPLITAKINLSNRT--FFVVGIL--GMCIGRMFLSMTSNFYVMMAIFLWLGLN 526
            .:.|.|:..|..:.||.....:..|.  ||...|:  |:|.....|:......|:.|:|..||..
Human   314 VMAFVDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFG 378

  Fly   527 KAFRTVFWSLIIPSYVPLKRLPAAAGLQLLMSGTFSMIFGPLIGLIRDHTSYAVTLNLLNALCVM 591
            .....:|.:|:  ..|...|..:|.||..::.....::..||.|.:.|.|.....:.:.....|:
Human   379 SVSSVLFETLM--DLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVV 441

  Fly   592 AFAGWYL---------------EDFIRARSRKSPPV 612
            |.:.|.|               |:..|.::|:|.|:
Human   442 AASVWLLIGNAINYRLLAKERKEENARQKTRESEPL 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8051	NP_001285434.1	MFS	86..>266	CDD:119392	46/210 (22%)
		MFS	<428..598	CDD:119392	43/173 (25%)
		MFS_1	440..>572	CDD:284993	35/135 (26%)
SLC16A7	XP_011537291.1	2A0113	15..484	CDD:273325	116/585 (20%)
		MFS	20..449	CDD:119392	105/550 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145479
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.750