Protein Alignment CG8051 and SLC16A3

DIOPT Version :9

• Sequence 1: NP_001285434.1
• Gene: CG8051 / 32925
• FlyBaseID: FBgn0031012
• Length: 616
• Species: Drosophila melanogaster
• Sequence 2: NP_001035887.1
• Gene: SLC16A3 / 9123
• HGNCID: 10924
• Length: 465
• Species: Homo sapiens
• Alignment Length: 549
• Identity: 101/549 - (18%)
• Similarity: 177/549 - (32%)
• Gaps: 162/549 - (29%)

  Fly    79 APDGGWGWLVSVASGVNILVTFALAQQFGILFRDRMAGLGISSSELTTIINTQIAVSAFTGLLNG 143
            ||||||||.|.....|....::|..:...:.|::.:...||..|:...|.:..:|:...||.|..
Human    15 APDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLAMLYGTGPLCS 79

  Fly   144 PLFRRYTYRVVALVGSVLTFLGLFWMVFADTFAVYIMSFSILYGFGRGLTVSASSLAVNTYFKVK 208
            ....|:..|.|.|||.:...||:....|..:.....::..::.|.|..|....|.:.:|.||..:
Human    80 VCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPSLIMLNRYFSKR 144

  Fly   209 RRTATAFQFGVAGLG-PI-VCPYFATYMLYE--FGVQGTTLLFAGASLHTIACSLIYQPVKWHVV 269
            |..|.    |:|..| |: :|.......|.:  :|.:|..|:..|..|:...|:.:.:|:
Human   145 RPMAN----GLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVCAALMRPL----- 200

  Fly   270 KRDRDAEALQQVQPLAEREDQDEDIIKNVVEPETPVLPRANDGWFGSRASLNSVGTRNRLNTWEK 334
                    :...||
Human   201 --------VVTAQP--------------------------------------------------- 206

  Fly   335 SDSNGHVELKRLSSKDSNPGRQLRSISVSHSIKEEEATGYNSDHEVQHTELTEKEKQELEDEKER 399
                        .|....|.|:|
Human   207 ------------GSGPPRPSRRL------------------------------------------ 217

  Fly   400 QRRKKLPFYMKVVIFFDMDLLRDITYVNLAVGITLINFVEINFAILTPFILS---DLGFNKDQIA 461
                           .|:.:.||..:|..||..::   :.:...:...|::|   |||....:.|
Human   218 ---------------LDLSVFRDRGFVLYAVAASV---MVLGLFVPPVFVVSYAKDLGVPDTKAA 264

  Fly   462 LAMSTLGFFDLVVR----FLIPLITAK---INLSNRTFFVVGILGMCIGRMFLSMTSNFYVMMAI 519
            ..::.|||.|:..|    |:..|...:   :.|.:.:.|..|:..:.      ..|:..|..:.:
Human   265 FLLTILGFIDIFARPAAGFVAGLGKVRPYSVYLFSFSMFFNGLADLA------GSTAGDYGGLVV 323

  Fly   520 F-LWLGLNKAFRTVFWSLIIPSYVPLKRLPAAAGLQLLMSGTFSMIFGPLIGLIRDHTS-YAVTL 582
            | ::.|::..........::.:.|...:..:|.||.|||.....::..|..|.:.|.|. |....
Human   324 FCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVF 388

  Fly   583 NLLNALCVMAFAGWYLEDFIRARSRKSPP 611
            .|..|..:.:.....|.:|...|.:...|
Human   389 ILAGAEVLTSSLILLLGNFFCIRKKPKEP 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8051	NP_001285434.1	MFS	86..>266	CDD:119392	44/183 (24%)
		MFS	<428..598	CDD:119392	36/181 (20%)
		MFS_1	440..>572	CDD:284993	29/142 (20%)
SLC16A3	NP_001035887.1	2A0111	8..444	CDD:331689	101/549 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	419..438

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145514
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.950