Protein Alignment CG8051 and SLC16A4

DIOPT Version :10

• Sequence 1: NP_573377.1
• Gene: CG8051 / 32925
• FlyBaseID: FBgn0031012
• Length: 616
• Species: Drosophila melanogaster
• Sequence 2: NP_004687.1
• Gene: SLC16A4 / 9122
• HGNCID: 10925
• Length: 487
• Species: Homo sapiens
• Alignment Length: 526
• Identity: 105/526 - (19%)
• Similarity: 202/526 - (38%)
• Gaps: 119/526 - (22%)

  Fly    81 DGGWGWLVSVASG-VNILV-----TFALAQQFGILFRDRMAGLGISSSELTTIINTQIAVSAFTG 139
            ||||||::.:... ||:.|     |||:   |.::|::...|    :||....|.:.::...|..
Human    16 DGGWGWMIVIHFFLVNVFVMGMTKTFAI---FFVVFQEEFEG----TSEQIGWIGSIMSSLRFCA 73

  Fly   140 LLNGPLFRRYTYRVVALVGSVL-----TFLGLFWMV-------FADTFAVYIMSFSILYGFGRGL 192
               |||        ||::..:|     :.||.|.:.       :|.:.....::..:|.|.|...
Human    74 ---GPL--------VAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAF 127

  Fly   193 TVSASSLAVNTYFKVKRRTATAFQFGVAGLGPIVCPYFATYMLYEFGVQGTTLLFAGASLHTIAC 257
            ....:::....|||.:...:||......||..::.| |..:::..:...|..:||...:|:.:..
Human   128 LYQVAAVVTTKYFKKRLALSTAIARSGMGLTFLLAP-FTKFLIDLYDWTGALILFGAIALNLVPS 191

  Fly   258 SLIYQPVKWHVVKRDRDAEALQQVQPLAEREDQDEDIIKNVVEPETPVLPRANDGWFGSRASLNS 322
            |::.:|:  |:...:                                     |.|.....:||::
Human   192 SMLLRPI--HIKSEN-------------------------------------NSGIKDKGSSLSA 217

  Fly   323 VGTRNRLNTWEKSDSNGHVELKRLSSKDS---NPGRQLRSISVSHSIKEEEATGYNSDHEVQHTE 384
            .|...     ..::::.| |.:..:.|||   ..|...::::||.:..||...|.|
Human   218 HGPEA-----HATETHCH-ETEESTIKDSTTQKAGLPSKNLTVSQNQSEEFYNGPN--------- 267

  Fly   385 LTEKEKQELEDEKERQRRKKLPFYMKVVIFFDMDLLRDITYVNLAVGITLINFVEINFAILTP-F 448
               :.:..|:.::|..  |.:.:..|.:  ||:.|.|:..:.     |...:|:....|...| |
Human   268 ---RNRLLLKSDEESD--KVISWSCKQL--FDISLFRNPFFY-----IFTWSFLLSQLAYFIPTF 320

  Fly   449 IL----SDLGFNKDQIALAMSTLGFFDLVVRFLIPLITAKINLSNRTFFVVGILGMC-IGRMFLS 508
            .|    ..||.:....:..:|..|..:.|.:.:...: |..|...:..:....|.:| |..:...
Human   321 HLVARAKTLGIDIMDASYLVSVAGILETVSQIISGWV-ADQNWIKKYHYHKSYLILCGITNLLAP 384

  Fly   509 MTSNFYVMMAIFLWLGLNKAFRTVFWSLIIPSYVPLKR---LPAAAGLQLLMSGTFSMIFGPLIG 570
            :.:.|.::|...:...:   |...:.:||:|..|.|.|   :....||....:|...:...|:.|
Human   385 LATTFPLLMTYTICFAI---FAGGYLALILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAG 446

  Fly   571 LIRDHT 576
            .:.|:|
Human   447 WLYDYT 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8051	NP_573377.1	MFS_MCT_SLC16	85..599	CDD:340910	101/522 (19%)
SLC16A4	NP_004687.1	MFS_MCT5	20..481	CDD:340979	101/522 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	206..250		10/49 (20%)