Protein Alignment CG8051 and SLC16A6

DIOPT Version :9

• Sequence 1: NP_001285434.1
• Gene: CG8051 / 32925
• FlyBaseID: FBgn0031012
• Length: 616
• Species: Drosophila melanogaster
• Sequence 2: XP_005257846.2
• Gene: SLC16A6 / 9120
• HGNCID: 10927
• Length: 527
• Species: Homo sapiens
• Alignment Length: 554
• Identity: 110/554 - (19%)
• Similarity: 210/554 - (37%)
• Gaps: 147/554 - (26%)

  Fly    80 PDGGWGWLVSVASGVNILVTFALAQQFGILFRDRMAGLGISSSELTTIINTQIAVSAFTGLLNGP 144
            |||||||.|:|:.....:.|:.:.:.||:.|.|.|.....|:|.::.||:..:.|..|:..|...
Human    23 PDGGWGWAVAVSFFFVEVFTYGIIKTFGVFFNDLMDSFNESNSRISWIISICVFVLTFSAPLATV 87

  Fly   145 LFRRYTYRVVALVGSVLTFLGLFWMVFADTFAVYIMSFSILYGFGRGLTVSASSLAVNTYFKVKR 209
            |..|:.:|:|.::|.:|...|:....|:...:...::..|:.|.|...:...:...::.||..:|
Human    88 LSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMYVAIGIISGLGYCFSFLPTVTILSQYFGKRR 152

  Fly   210 RTATAFQ-----FGVAGLGPIVCPYFA----TYMLYEFGVQGTTLLFAGASLHTIACSLIYQPVK 265
            ...||..     |.|....|.:.....    .|.|...|:....::..||.|..|   .|..|..
Human   153 SIVTAVASTGECFAVFAFAPAIMALKERIGWRYSLLFVGLLQLNIVIFGALLRPI---FIRGPAS 214

  Fly   266 WHVVKRDRDAEALQQVQPLAEREDQDEDIIKNVVEPETPVLPRANDGWFGSRASLNSVGTRNRLN 330
            ..:|.::...||    |.:.|.|.                          :|.|::|:.:...|.
Human   215 PKIVIQENRKEA----QYMLENEK--------------------------TRTSIDSIDSGVELT 249

  Fly   331 TWEKS-DSNGHVELKRLSSKDSNPGRQLRSISVSHSIKEEEATGYNSDHEVQHTELTEKEKQELE 394
            |..|: .::.::||:        |...::.:.|..|.:..|
Human   250 TSPKNVPTHTNLELE--------PKADMQQVLVKTSPRPSE------------------------ 282

  Fly   395 DEKERQRRKKLPFYMKVVIFFDMDLLRDITYVNLAV-GITLINFVEINFAILTPFILS---DLGF 455
                    ||.|       ..|..:|::.:::..|: |:    |..:.|...:.:|:.   .||.
Human   283 --------KKAP-------LLDFSILKEKSFICYALFGL----FATLGFFAPSLYIIPLGISLGI 328

  Fly   456 NKDQIALAMSTLGFFDLVVRFLIPLITAKINLSNRTFFVVGILGMCIGRMFLSMTSNFYVMMAIF 520
            ::|:.|..:||:...::..|     |.|...|:...          |.::::.:.....:.:::|
Human   329 DQDRAAFLLSTMAIAEVFGR-----IGAGFVLNREP----------IRKIYIELICVILLTVSLF 378

  Fly   521 LWLGLNKAFRTVFWSLIIPS-------------YVPL---------KRLPAAAGLQLLMSGTFSM 563
            .:     .|.|.||.|:..|             ::||         :::.:|||:.:.:.....:
Human   379 AF-----TFATEFWGLMSCSIFFGFMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYIFIQSIAGL 438

  Fly   564 IFGPLIGLIRDHTS------YAVTLNL-LNALCV 590
            ...||.||:.|.:.      |:....: |.|:|:
Human   439 AGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCL 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8051	NP_001285434.1	MFS	86..>266	CDD:119392	44/188 (23%)
		MFS	<428..598	CDD:119392	37/196 (19%)
		MFS_1	440..>572	CDD:284993	28/156 (18%)
SLC16A6	XP_005257846.2	2A0113	23..512	CDD:273325	110/554 (20%)
		MFS	33..476	CDD:119392	102/544 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145505
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.740