Protein Alignment CG8051 and MCH4

DIOPT Version :9

• Sequence 1: NP_001285434.1
• Gene: CG8051 / 32925
• FlyBaseID: FBgn0031012
• Length: 616
• Species: Drosophila melanogaster
• Sequence 2: NP_014522.1
• Gene: MCH4 / 854030
• SGDID: S000005479
• Length: 501
• Species: Saccharomyces cerevisiae
• Alignment Length: 569
• Identity: 113/569 - (19%)
• Similarity: 198/569 - (34%)
• Gaps: 169/569 - (29%)

  Fly    65 KKKRDKSDL----------------------GEDFVAPDGGW-GWLVSVASGVNILVTFALAQQF 106
            ||..|:.||                      .:|...||||. .|||...:.:.::..|.|....
Yeast    53 KKNSDQVDLDVNKLTNVTSRVLNTPEASLIYDDDREFPDGGLKAWLVVFGAFMGLVPVFGLINSL 117

  Fly   107 G----ILFRDRMAGLGISSSELTTIINTQIAVSAFTGLLNGPLFRRYTYRVVALVGSVLTFLGLF 167
            |    .:.:.::|  .||||.::.|.:..:|:|..:.:|:|..|.|.....:...|:|:...|||
Yeast   118 GAIESYISKHQLA--NISSSTISWIFSLYLAISFLSCILSGGYFDRNGSIGLMCTGTVIYAGGLF 180

  Fly   168 WMVFADTFAVYIMSFSILYGFGRGLTVSASSLAVNTYFKVKRRTATAFQFGVAGLGPIVCPYFAT 232
            .:....:...:|::||:..|.|.|:.::.....|.|:|..:|..||:.......:|.||.|....
Yeast   181 ALANCKSVWQFILAFSVCSGLGTGILMTPLIGTVATWFLKRRGIATSISTMGGSIGGIVFPIMLR 245

  Fly   233 YMLYEFGVQGTTLLFAGASLHTIACSLIYQPVKWHVVKRDRDAEALQQVQPLAEREDQDEDIIKN 297
            .:..|.|.|....:.:...|..:.|:        .|:.|:|....   |||...:.:..:..|.:
Yeast   246 KLYKEVGFQWAIRILSFICLTCLICA--------SVLARERTKPV---VQPFKSKAEVAKWYISS 299

  Fly   298 VVE----PETPVLPRANDGWFGSRASLNSVGTRNRLNTWEKSDSNGHVELKRLSSKDSNPGRQLR 358
            |..    .|...|..|....| :.:||.|..|                              .|.
Yeast   300 VFNWRYFLEGKFLFVAIGASF-AESSLTSCAT------------------------------YLA 333

  Fly   359 SISVSHSIKEEEATGYNSDHEVQHTELTEKEKQELEDEKERQRRKKLPFYM--KVVIFFDMDLLR 421
            |.|::....|          .|.:|.:|......:       ..:.:|.|.  |.:..|::::
Yeast   334 SYSMTRGNTE----------NVAYTMITASNAVGI-------LGRYIPGYFADKFIGRFNVEI-- 379

  Fly   422 DITYVNLAVGITLINFVEINFAILTPFILSDLGFNKDQIALAMSTLGFFDLVVRFLIPLITAKIN 486
                      ||:......||.:..||     |.|...:...:...||
Yeast   380 ----------ITISMAALFNFVMWLPF-----GGNTKVLWAYVCLWGF----------------- 412

  Fly   487 LSNRTFFVVGILGMCIGRMFLSMTSNFYVMMAIFLWLGLNKAFRTVFWSLIIPSYVPLKRLPAAA 551
               .|..::.:..:|||:  :|.|::|            .|.:.||:   ::.:.|.:..||
Yeast   413 ---STGSILSLTPVCIGQ--ISKTTDF------------GKRYATVY---LLQALVTIPVLP--- 454

  Fly   552 GLQLLMSGTFSMIFGPLI--GLIRDHTSYAVTLNLLNALCVMAFAGWYL 598
                        |.|.||  |.:.::..:.:    .|:..:.|.|..|:
Yeast   455 ------------IGGTLIGKGTVANYNHFII----FNSALMAAGAACYI 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8051	NP_001285434.1	MFS	86..>266	CDD:119392	44/183 (24%)
		MFS	<428..598	CDD:119392	31/171 (18%)
		MFS_1	440..>572	CDD:284993	26/133 (20%)
MCH4	NP_014522.1	MFS_MCT_SLC16	96..490	CDD:340910	103/526 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343223
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.800