Protein Alignment CG8051 and MCH2

DIOPT Version :9

• Sequence 1: NP_001285434.1
• Gene: CG8051 / 32925
• FlyBaseID: FBgn0031012
• Length: 616
• Species: Drosophila melanogaster
• Sequence 2: NP_012701.2
• Gene: MCH2 / 853659
• SGDID: S000001704
• Length: 473
• Species: Saccharomyces cerevisiae
• Alignment Length: 567
• Identity: 105/567 - (18%)
• Similarity: 176/567 - (31%)
• Gaps: 209/567 - (36%)

  Fly    80 PDGGWGWLVSVASGVNILVTFALAQQFGI-----LFRDRMAGLGISSSELTTIINTQIAVSAFT- 138
            ||||:||.:.:|..:....|:.....:.|     |..:..||    .|:|.   ...|...||:
Yeast    36 PDGGYGWFILLAFILYNFSTWGANSGYAIYLAHYLENNTFAG----GSKLD---YASIGGLAFSC 93

  Fly   139 GLLNGPLFRRYTYRVVA---LVGSVLTFLG--LFWMVFADTFAVYIMSFSILYGFGRGLTVSASS 198
            ||...|:. .:.|.:.:   ::|..:.|.|  |....|:.|.....::..:|.|||.......|.
Yeast    94 GLFFAPVI-TWLYHIFSIQFIIGLGILFQGAALLLAAFSVTLWEIYLTQGVLIGFGLAFIFIPSV 157

  Fly   199 LAVNTYFKVKRRTATAFQFGVAGLGPIVCPYFATYMLYEFGVQGTTLLFAGASLHTIACSLIYQP 263
            ..:..:|:.||..|:......:|||.||         :..|:|..               |..:.
Yeast   158 TLIPLWFRNKRSLASGIGTAGSGLGGIV---------FNLGMQSI---------------LQKRG 198

  Fly   264 VKWHVVKRDRDAEALQQVQPLAEREDQDEDIIKNVVEPETPVLPRANDGWFGSRASLNSVGTRNR 328
            |||.::     |:.:                                     ...||:::...
Yeast   199 VKWALI-----AQCI-------------------------------------ICTSLSTIALM-- 219

  Fly   329 LNTWEKSDSNGHVELKRLSSKDSNPGRQLRSISVSHSIKEEEATGYNSDHEVQHTELTEKEKQEL 393
                                                                    ||....|.|
Yeast   220 --------------------------------------------------------LTRTTHQGL 228

  Fly   394 EDEKERQRRKKLPFYMKVVIFFDMDLLRDITYVNLAVGIT--LINFVEINFAILTPFILSD---- 452
                 ||.::...|.:     .|.|:|.     |.||.:.  .::|..:.:.:|. :.|||
Yeast   229 -----RQHKRSYKFEL-----LDYDVLS-----NFAVWLLFGFVSFAMLGYVVLL-YSLSDFTVS 277

  Fly   453 LGFNKDQIALAMSTLGFFDLVVRFLIPLITAKINLSNRTFFVVGILGMCIGRMFLSMTSNFYVMM 517
            ||:...|.:.....:....|:.|.::..|..|..     ...||::              .:::|
Yeast   278 LGYTSKQGSYVSCMVSVGSLLGRPIVGHIADKYG-----SLTVGMI--------------LHLVM 323

  Fly   518 AIFLW--------LGLNKAFRTVFWSL----------IIPSYVPLKRLPAAAGLQLLMSGTFSMI 564
            ||..|        |....||..:..|:          |:...|.|::||...|...:....|:::
Yeast   324 AILCWAMWIPCKNLATAIAFGLLVGSIMGTIWPTIASIVTRIVGLQKLPGTFGSTWIFMAAFALV 388

  Fly   565 FGPLIGLIRDHTS------YAVTLNLLNALCVMAFAGWYLEDFIRAR 605
             .|:|||....|.      |...:.:..|...::...|.|..||.||
Yeast   389 -APIIGLELRSTDTNGNDYYRTAIFVGFAYFGVSLCQWLLRGFIIAR 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8051	NP_001285434.1	MFS	86..>266	CDD:119392	40/190 (21%)
		MFS	<428..598	CDD:119392	39/199 (20%)
		MFS_1	440..>572	CDD:284993	31/153 (20%)
MCH2	NP_012701.2	MFS_MCT_SLC16	41..428	CDD:340910	96/554 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
TreeFam	0	0.000	Not matched by this tool.
	4	3.910