Protein Alignment CG8051 and SLC16A2

DIOPT Version :9

• Sequence 1: NP_001285434.1
• Gene: CG8051 / 32925
• FlyBaseID: FBgn0031012
• Length: 616
• Species: Drosophila melanogaster
• Sequence 2: NP_006508.2
• Gene: SLC16A2 / 6567
• HGNCID: 10923
• Length: 539
• Species: Homo sapiens
• Alignment Length: 591
• Identity: 114/591 - (19%)
• Similarity: 190/591 - (32%)
• Gaps: 209/591 - (35%)

  Fly    25 PEEQAE-QLLPKNGSAGQTKIAP-PTHTHSIAAASVPQKVPAKKKRDKSDLGEDFVAPDGGWGWL 87
            ||.|.| |.||..        || |...........|:..|..:.|..:   ..|..|:||:||:
Human    49 PEPQPEPQPLPDP--------APLPELEFESERVHEPEPTPTVETRGTA---RGFQPPEGGFGWV 102

  Fly    88 VSVASGVNILVTFALAQQFGILF---------RDRMA---GLGISSSELTTIINTQIAVSAFTGL 140
            |..|:.......|.:....|||:         ::|..   ...:.:..:..|......||.||.
Human   103 VVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNRQVEFQAAWVGALAMGMIFFCSPIVSIFTD- 166

  Fly   141 LNGPLFRRYTYRVVALVGSVLTFLGLFWMVFADTFAVYIMSFSILYGFGRGLTVSASSLAVNTYF 205
                   |...|:.|..|:.:.|:||....|..:.::...::.||:|.|.......|.:.:..||
Human   167 -------RLGCRITATAGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFAFQPSLVILGHYF 224

  Fly   206 KVKRRTATAFQFGVAGLGPIVCPYFATYMLYEFGVQ---------GTTLLFAGASLHTIACSLIY 261
              :||...|  .||...|..:......:::...|.:         .:|.:|.     .:..||.|
Human   225 --QRRLGLA--NGVVSAGSSIFSMSFPFLIRMLGDKIKLAQTFQVLSTFMFV-----LMLLSLTY 280

  Fly   262 QPVKWHVVKRDRDAEALQQVQPLAEREDQDEDIIKNVVEPETPVLPRANDGWFGSRASLNSVGTR 326
            :                                         |:||
Human   281 R-----------------------------------------PLLP------------------- 285

  Fly   327 NRLNTWEKSDSNGHVELKRLSSKDSNPGRQLRSISVSHSIKEEEATGYNSDHEVQHTELTEKEKQ 391
                                ||:|:...|.:|::
Human   286 --------------------SSQDTPSKRGVRTL------------------------------- 299

  Fly   392 ELEDEKERQRRKKLPFYMKVVIFFDMDLLRDITYVNLAVGIT------------LINFVEINFAI 444
                   .||     |..::..:|:|.:.|..||...|.||.            |:.:||..|:.
Human   300 -------HQR-----FLAQLRKYFNMRVFRQRTYRIWAFGIAAAALGYFVPYVHLMKYVEEEFSE 352

  Fly   445 L--TPFILSDLGFNKDQIALAMSTLGFFDLVVRFLIPLITA--KINLSNRTFFVVGILGMCIGRM 505
            :  |..:|..:|          :|.|...||...:...|..  ||.|...:|.::|::.|.|
Human   353 IKETWVLLVCIG----------ATSGLGRLVSGHISDSIPGLKKIYLQVLSFLLLGLMSMMI--- 404

  Fly   506 FLSMTSNFYVMMAIFLWLGL-NKAFRTVFWSLIIPSYVPLKRLPAAAGLQLLMSGTFSMIFG-PL 568
              .:..:|..::.:.|:||| :..|.|:...:......|::...|...|..:|:  ..||.| |:
Human   405 --PLCRDFGGLIVVCLFLGLCDGFFITIMAPIAFELVGPMQASQAIGYLLGMMA--LPMIAGPPI 465

  Fly   569 IGLIRD 574
            .||:|:
Human   466 AGLLRN 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8051	NP_001285434.1	MFS	86..>266	CDD:119392	40/200 (20%)
		MFS	<428..598	CDD:119392	40/165 (24%)
		MFS_1	440..>572	CDD:284993	32/137 (23%)
SLC16A2	NP_006508.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..92		13/53 (25%)
		2A0113	86..513	CDD:273325	102/546 (19%)
		MFS	101..498	CDD:119392	96/528 (18%)
		DUF1564	<286..>334	CDD:284922	16/90 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	508..539

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145511
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750